Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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Dental implant treatment after healing of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in the same region: a case report

  • Kim, Ji-Wan (Department of Oral and Maxillofacial Surgery, Asan Medical Center) ;
  • Baik, Jin (Department of Prosthodontics, Asan Medical Center) ;
  • Jeon, Ju-Hong (Department of Oral and Maxillofacial Surgery, Asan Medical Center)
  • Received : 2016.01.13
  • Accepted : 2016.05.04
  • Published : 2016.06.30
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Abstract

Although pathophysiology, incidence, and factors associated with the development of bisphosphonate-related osteonecrosis of the jaw (BRONJ) and management strategies for patients treated with bisphosphonates or patients with BRONJ are well-established, few guidelines or recommendations are available for patients with a history of successfully healed BRONJ. We present a case of successful dental implant treatment after healing of BRONJ in the same region of the jaw, and speculate that implant placement is possible after healing of BRONJ surgery in select cases.

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References

  1. Kushner GM, Alpert B. Osteomyelitis, osteoradionecrosis and BRONJ. In: Miloro M, Ghali GE, Larsen PE, Waite PD, eds. Peterson's principles of oral and maxillofacial surgery. 3rd ed. Shelton: People's medical publishing house; 2012:861-74.
  2. Ruggiero SL, Dodson TB, Assael LA, Landesberg R, Marx RE, Mehrotra B. American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws--2009 update. J Oral Maxillofac Surg 2009;67(5 Suppl): 2-12. https://doi.org/10.1016/S0278-2391(09)01877-1
  3. Advisory Task Force on Bisphosphonate-Related Ostenonecrosis of the Jaws, American Association of Oral and Maxillofacial Surgeons. American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg 2007;65:369-76. https://doi.org/10.1016/j.joms.2006.11.003
  4. Marx RE. Oral and intravenous bisphosphonate-induced osteonecrosis of the jaws: history, etiology, prevention, and treatment. 2nd ed. Chicago: Quintessence Publishing; 2011.
  5. Rasmusson L, Abtahi J. Bisphosphonate associated osteonecrosis of the jaw: an update on pathophysiology, risk factors, and treatment. Int J Dent 2014;2014:471035.
  6. Fliefel R, Tröltzsch M, Kuhnisch J, Ehrenfeld M, Otto S. Treatment strategies and outcomes of bisphosphonate-related osteonecrosis of the jaw (BRONJ) with characterization of patients: a systematic review. Int J Oral Maxillofac Surg 2015;44:568-85. https://doi.org/10.1016/j.ijom.2015.01.026
  7. Tallarico M, Canullo L, Xhanari E, Meloni SM. Dental implants treatment outcomes in patient under active therapy with alendronate: 3-year follow-up results of a multicenter prospective observational study. Clin Oral Implants Res 2015. doi: 10.1111/clr.12662. [Epub ahead of print]
  8. Rugani P, Kirnbauer B, Acham S, Truschnegg A, Jakse N. Implant placement adjacent to successfully treated bisphosphonate-related osteonecrosis of the jaw (BRONJ). J Oral Implantol 2015;41:377-81. https://doi.org/10.1563/AAID-JOI-D-13-00178
  9. Kwon TG, Lee CO, Park JW, Choi SY, Rijal G, Shin HI. Osteonecrosis associated with dental implants in patients undergoing bisphosphonate treatment. Clin Oral Implants Res 2014;25:632-40.
  10. Memon S, Weltman RL, Katancik JA. Oral bisphosphonates: early endosseous dental implant success and crestal bone changes. A retrospective study. Int J Oral Maxillofac Implants 2012;27:1216-22.
  11. Dixon RB, Tricker ND, Garetto LP. Bone turnover in elderly canine mandible and tibia. J Dent Res 1997;76:336.
  12. Madrid C, Sanz M. What impact do systemically administrated bisphosphonates have on oral implant therapy? A systematic review. Clin Oral Implants Res 2009;20 Suppl 4:87-95.
  13. Ata-Ali J, Ata-Ali F, Peñarrocha-Oltra D, Galindo-Moreno P. What is the impact of bisphosphonate therapy upon dental implant survival? A systematic review and meta-analysis. Clin Oral Implants Res 2016;27:e38-46. https://doi.org/10.1111/clr.12526