The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
권호 표지
DOI QR코드

DOI QR Code

The Effect of Jeokbaekhaogwanjung-tang Herbal Acupuncture Solution on the Immune Activity of Spleen Cells of Aged Rats

적백하오관중탕 약침액이 노화 흰쥐 비장세포의 면역활성에 미치는 영향

  • Lee, Hyun-Suk (Department of Meridians & Acupoints, College of korean Medicine, Daejeon University) ;
  • Choi, Kang-Min (Department of Meridians & Acupoints, College of korean Medicine, Daejeon University) ;
  • Yim, Yun-Kyoung (Department of Meridians & Acupoints, College of korean Medicine, Daejeon University)
  • 이현석 (대전대학교 한의과대학 경락경혈학교실) ;
  • 최강민 (대전대학교 한의과대학 경락경혈학교실) ;
  • 임윤경 (대전대학교 한의과대학 경락경혈학교실)
  • Received : 2016.02.16
  • Accepted : 2016.03.28
  • Published : 2016.03.31
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: The purpose of this study was to investigate the effect of Jeokbaekhaogwanjung-tang (JGT) distillate on the immune activity of spleen cells of aged rats. Methods: Spleen cells of 10w, 52w 72w old SD rats were cultured and treated with JGT distillate and the levels of IL-2, IL-4, IL-10 and IFN-${\gamma}$ were measured. Results: 1. The levels of IL-2 and IFN-${\gamma}$ in the spleen cells of 52w old rats were significantly decreased by JGT treatment. 2. The level of IFN-${\gamma}$ in the spleen cells of 72w old rats were significantly decreased by JGT treatment. Conclusion: These results suggest that Jeokbaekhaogwanjung-tang distillate has an immune regulative effect by way of suppressing the change of immune activity caused by aging in rats.

Keywords

References

  1. Cho JY. Geriatric medicine. 2nd edition. Seoul : HanKook Book. 2006:40-41.
  2. Koo BS. Anti-Aging medicine basic principles and clinical practice. Seoul : Calvin Book. 2003:37-44.
  3. Kang TS, Kim SH, Kim YH, Kim YK, Kim YH, Kim YH. Clinical Immunology. Seoul :ChungGuMoonHwaSa. 2005:11-23.
  4. Kim KH. Preventive Oriental Medicine. Seoul:SeoWonDang. 2002:405-480.
  5. Choi BC, Ahn TW. Anti-Oxidant Effect of Hyangsayangyitang Decoction in Stomach, Spleen and Pancreas Cell of SD Rats. J Sasang Constitut Med. 2008;20(2):72-84.
  6. Lee HE, Ahn TW. Anti-Oxidant Effect of Hyeongbangjiwhang-tang Decoction in Kidney, Bladder and Spleen cell of SD Rats. J Sasang Constitut Med. 2008;20(2):85-97.
  7. Lee SY, Ahn TW. Anti-aging Effect of Tae-Eumin's Nocyongdaebo-tang(NYD) in Aged Rats. J Sasang Constitut Medicine. 2008;20(2):58-71.
  8. Sun TC, Ahn TW. Anti-aging Effect of Sipyimigwanjungtang in Aged Rats. J Sasang Constitut Medicine. 2008;20(2):98-110.
  9. Ryu CR, Song JM. Immunoregulatory Action Soeumin Seungyangikkitang. J Sasang Constitut Med. 2001;13(3):102-113.
  10. Lim JP, Ahn TW. The Anti-Oxidant and Immune-regulatory Effect of Chungsimyeonja-tang in Aged Rat. J Sasang Constitut Med. 2007;19(3):227-241.
  11. Ryu JY. Four-Constitution Medicine Lecture. Gyeonggi-do : Daesung Publishing Co. 2003:407.
  12. United Nations Development Programme. Human Development Report 2014. New York :UNDP. 2014;160.
  13. Son JR. Free radical & Antioxidant. Seoul :Biomedical. 2004 : 130.
  14. Jang HS. Adult psychology: Adult development, aging & death. Seoul : ParkYoungSa. 2006:78.
  15. Lim IS. The Approach of Antioxidant, Endocrine, & Immune System on Exercise & Aging. Exercise Science. 2002;11(1):35-51.
  16. Kim YD. The newest Immunity. Seoul :JipMoonDang. 1982:33.
  17. Choi YH. The elderly and health. Seoul : HyunMoonSa. 2000:4-5,38-45.
  18. Du HK. Oriental Kidney System Internal Medicine. Seoul : Institute of the oriental science. 1991:1093-1100, 1325-1383.
  19. Lim EM, Lee SH. Oriental Medicine looked at the concept of immune. The Journal of the Korea Institute of Oriental Medical Informatics. 2006;12(1):129-145.
  20. Shin HI. an annotated edition of Longevity and Life Preservation in Eastern Medicine : Sang. Gyeonggi-do : Daesung Publishing Co. 2003:50-51, 616-617
  21. Jang EC, Youn WK, Lee SK. Effect of Age on Glucose Metabolism of Skeletal Muscle in Rats. Yeungnam Univ. J. of Med. 2001;18(1):94-100. https://doi.org/10.12701/yujm.2001.18.1.94
  22. Park SK, Lee HJ, Kim HT, Whang WW. An experimental study of oriental medicine on cure for dementia : the effect of Jowiseungcheongtang and Hyungbangjihwangtang on cure for aged rats. J. of Oriental Neuropsychiatry. 1998;9(2):19-35.
  23. Pyo SN, Son EH. Introduction to Immunology. Seoul : ShinIlBooks. 2008: 145-158.
  24. Lee GN, Kwon OH. Clinical Laboratory File. 3rd edition. Seoul : Medical Publisher. 2003:716-732.
  25. Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL, et al. Harrison's Internal Medicine. 1st Ed. Seoul:MIP Publishers. 2006:2079-2107.
  26. Pyo SN, Son EH. Introduction to Immunology. Seoul:Shinil Books. 2008:152-158.
  27. Seo S. Clinical Immunology. 2nd edition. Seoul:Korea Medical Book Publisher. 2009:121, 126-131.

Cited by

  1. 적백하오관중탕 증류액이 노화 흰쥐 비장세포의 항산화능에 미치는 영향 vol.31, pp.4, 2016, https://doi.org/10.6116/kjh.2016.31.4.35.