Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Flavonoid Glycosides from the Flowers of Pulsatilla koreana Nakai

  • Seo, Kyeong-Hwa (Department of Oriental Medicine Biotechnology, Kyung Hee University) ;
  • Jung, Jae-Woo (Department of Oriental Medicine Biotechnology, Kyung Hee University) ;
  • Nhan, Nguyen Thi (Department of Oriental Medicine Biotechnology, Kyung Hee University) ;
  • Lee, Youn-Hyung (Department of Horticultural Biotechnology, Kyung Hee University) ;
  • Baek, Nam-In (Department of Oriental Medicine Biotechnology, Kyung Hee University)
  • Received : 2015.07.20
  • Accepted : 2015.08.17
  • Published : 2016.03.31
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Abstract

Extraction and fractionation of Pulsatilla koreana flowers followed by, repeated open column chromatography for EtOAc and n-BuOH fractions yielded four flavonoid glycosides, namely, astragalin (1), tiliroside (2), buddlenoide A (3), and apigenin-7-O-(3"-E-p-coumaroyl)-glucopyranoside (4). The chemical structures of these flavonoid glycosides were elucidated on the basis of various spectroscopic methods including electronic ionization mass spectrometry (EI-MS), 1D NMR ($^1H$, $^{13}C$, DEPT), 2D NMR (gCOSY, gHSQC, gHMBC), and infrared (IR) spectrometry. This study represents the first report of the isolation of the flavonoid glycosides from the flowers of P. koreana.

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References

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