References
- Barker CA, Bishop AJ, Chang M, et al (2013). Valproic acid use during radiation therapy for glioblastoma associated with improved survival. Int J Radiat Oncol Biol Phys, 86, 504-9. https://doi.org/10.1016/j.ijrobp.2013.02.012
- Beaumont A, Whittle IR (2000). The pathogenesis of tumour associated epilepsy. Acta Neurochir (Wien), 142, 1-15. https://doi.org/10.1007/s007010050001
- Berendsen S, Varkila M, Kroonen J, et al (2015). Prognostic relevance of epilepsy at presentation in glioblastoma patients. Neuro Oncol, [Epub ahead of print]
- Brown SL, Kolozsvary A, Liu J, et al (2008). Histone deacetylase inhibitors protect against and mitigate the lethality of totalbody irradiation in mice. Radiat Res, 169, 474-8. https://doi.org/10.1667/RR1245.1
- Chaichana KL, Parker SL, Olivi A, et al (2009). Long-term seizure outcomes in adult patients undergoing primary resection of malignant brainastrocytomas. Clinical article. J Neurosurg, 111, 282-92. https://doi.org/10.3171/2009.2.JNS081132
- Chateauvieux S, Morceau F, Dicato M, et al (2010). Molecular and therapeutic potential and toxicity of valproic acid. J Biomed Biotechnol, 2010, 479364.
- Fu J, Shao CJ, Chen FR, et al (2010). Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines. Neuro Oncol, 12, 328-40. https://doi.org/10.1093/neuonc/nop005
- Guthrie GD, Eljamel S (2013). Impact of particular antiepileptic drugs on the survival of patients with glioblastoma multiforme. J Neurosurg, 118, 859-65. https://doi.org/10.3171/2012.10.JNS12169
- Hosein AN, Lim YC, Day B, et al (2015). The effect of valproic acid in combination with irradiation and temozolomide on primary human glioblastoma cells. J Neurooncol, 122, 263-71. https://doi.org/10.1007/s11060-014-1713-x
- Kerkhof M, Dielemans JC, van Breemen MS, et al. (2013). Effect of valproic acid on seizure control and on survival in patients with glioblastoma multiforme. Neuro Oncol, 15, 961-7. https://doi.org/10.1093/neuonc/not057
- Krauze AV, Myrehaug SD, Chang MG, et al (2015). A phase 2 study of concurrent radiation therapy, temozolomide, and the histone deacetylase inhibitor valproic acid for patients with glioblastoma. Int J Radiat Oncol Biol Phys, 92, 986-92. https://doi.org/10.1016/j.ijrobp.2015.04.038
- Louis DN, Ohgaki H, Wiestler OD, et al (2007). The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol, 114, 97-109. https://doi.org/10.1007/s00401-007-0243-4
- Oberndorfer S, Piribauer M, Marosi C, et al (2005). P450 enzyme inducing and non-enzyme inducing antiepileptics in glioblastoma patients treated withstandard chemotherapy. J Neurooncol, 72, 255-60. https://doi.org/10.1007/s11060-004-2338-2
- Oike T, Suzuki Y, Sugawara K, et al (2013). Radiotherapy plus concomitant adjuvant temozolomide for glioblastoma: Japanese mono-institutional results. PLoS One, 8, 78943. https://doi.org/10.1371/journal.pone.0078943
- Oike T, Ogiwara H, Amornwichet N, et al (2014). Chromatinregulating proteins as targets for cancer therapy. J Radiat Res, 55, 613-28. https://doi.org/10.1093/jrr/rrt227
- Ostrom QT, Gittleman H, Liao P, et al. (2014). CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol, 16, 1-63. https://doi.org/10.1093/neuonc/not237
- Pont LM, Naipal K, Kloezeman JJ, et al. (2015). DNA damage response and anti-apoptotic proteins predict radiosensitization efficacy of HDAC inhibitors SAHA and LBH589 in patient-derived glioblastoma cells. Cancer Lett, 356, 525-35. https://doi.org/10.1016/j.canlet.2014.09.049
- Rosati A, Poliani PL, Todeschini A, et al (2013). Glutamine synthetase expression as a valuable marker of epilepsy and longer survival in newly diagnosed glioblastoma multiforme. Neuro Oncol, 15, 618-25. https://doi.org/10.1093/neuonc/nos338
- Rubner Y, Muth C, Strnad A, et al (2014). Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines. Radiat Oncol, 9, 89. https://doi.org/10.1186/1748-717X-9-89
- Shao CJ, Wu MW, Chen FR, et al. (2012). Histone deacetylase inhibitor, 2-propylpentanoic acid, increases the chemosensitivity and radiosensitivity of human glioma cell lines in vitro. Chin Med J, 125, 4338-43.
- Stark AM, van de Bergh J, Hedderich J, et al (2012). Glioblastoma: clinical characteristics, prognostic factors and survival in 492 patients. Clin Neurol Neurosurg, 114, 840-5. https://doi.org/10.1016/j.clineuro.2012.01.026
- Stupp R, Mason WP, van den Bent MJ, et al (2005). Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med, 352, 987-96. https://doi.org/10.1056/NEJMoa043330
- Stupp R, Hegi ME, Mason WP, et al (2009). Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTCNCIC trial. Lancet Oncol, 10, 459-66. https://doi.org/10.1016/S1470-2045(09)70025-7
- Szczepanek D, Marchel A, Moskala M, et al. (2013). Efficacy of concomitant and adjuvant temozolomide in glioblastoma treatment. A multicentre randomized study. Neurol Neurochir Pol, 47, 101-8.
- Thotala D, Karvas RM, Engelbach JA, et al (2015). Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells. Oncotarget, 6, 35004-22.
-
Van Nifterik KA, Van den Berg J, Slotman BJ, et al (2012). Valproic acid sensitizes human glioma cells for temozolomide and
${\gamma}$ -radiation. J Neurooncol, 107, 61-7. https://doi.org/10.1007/s11060-011-0725-z - Vecht CJ, Kerkhof M, Duran-Pena A (2014). Seizure prognosis in brain tumors: new insights and evidence-based management. Oncologist, 19, 751-9. https://doi.org/10.1634/theoncologist.2014-0060
- Weller M, Gorlia T, Cairncross JG, et al (2011). Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma. Neurol, 77, 1156-64. https://doi.org/10.1212/WNL.0b013e31822f02e1
- Zhou Y, Xu Y, Wang H, et al (2014). Histone deacetylase inhibitor, valproic acid, radiosensitizes the C6 glioma cell line in vitro. Oncol Lett, 7, 203-8. https://doi.org/10.3892/ol.2013.1666
- Zhou Y, Niu J, Li S, et al (2015). Radioprotective effects of valproic acid, a histone deacetylase inhibitor, in the rat brain. Biomed Rep, 3, 63-9. https://doi.org/10.3892/br.2014.367
Cited by
- Repurposing old drugs in oncology: Opportunities with clinical and regulatory challenges ahead pp.02694727, 2019, https://doi.org/10.1111/jcpt.12759