Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Skin Health Effect of DuOligo Intake Containing Lactulose

락툴로스 함유 듀올리고 섭취에 의한 피부개선 효과

  • Hong, Yang-Hee (Department of Beauty Art, Suwon Women's University) ;
  • Jung, Eun Young (Department of Home Economic Education, Jeonju University) ;
  • Suh, Hyung Joo (School of Biosystem and Biomedical Science, Korea University) ;
  • Han, Sung Hee (Institute for Biomaterials, Korea University, Korea University)
  • 홍양희 (수원여자대학교 미용예술과) ;
  • 정은영 (전주대학교 가정교육과) ;
  • 서형주 (고려대학교 바이오시스템의과학부) ;
  • 한성희 (고려대학교 생물신소재연구소)
  • Received : 2016.10.11
  • Accepted : 2016.12.05
  • Published : 2016.12.30
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Abstract

In this study, the skin-improving effect was investigated through the oral intake of DuOligo (51.67% lactulose and 15.8% galactooligosaccharides). Thirty seven healthy women (40~60 in ages) were divided into placebo group (dextrin) and treatment group (DuOligo group), and each group was given a sample for oral intake for 8 weeks. After that, corneometer value, transepidermal water loss (TEWL), melanin index, erythema index, and wrinkle index were measured. As a result, moisture content of DuOligo group increased 38.22% than control group after 8 weeks significantly (p < 0.01). The TEWL of control group decreased by $3.39g/h/m^2$ after 8 weeks but the TEWL of DuOligo group decreased by $5.32g/h/m^2$ after 8 weeks. The melanin index of the control group was significantly increased with times, but the melanin index of the DuOligo group did not show any significant difference with times. The total wrinkles, length of total wrinkles, number of wrinkles, and depth of wrinkles significantly decreased (p < 0.05) compared to the control group. These results suggested that the applicability of DuOligo as a skin improving functional material was confirmed.

본 연구에서는 락툴로스(lactulose) 51.67%와 갈락토올리고당(galactooligo saccharides) 15.8%로 이루어진 듀올리고(DuOligo)의 섭취를 통하여 피부개선 효능을 조사하였다. 40~60 대의 건강한 여성 37명을 대상으로 대조군(덱스트린)과 실험군(듀올리고군)으로 나누어 각각 8주 동안 섭취 후, 수분보유량, 경표피수 분손실량, 멜라닌지수, 홍반지수와 주름지수를 측정하였다. 그 결과, 듀올리고 섭취 8주 후의 수분 보유량은 대조군에 비하여 수분 보유량이 38.22% 유의적으로 증가하였다(p < 0.01). 대조군의 경피수분손실량은 8주후 $3.39g/h/m^2$로 감소한데 비하여 듀올리고군의 경피수분손실량은 8주후 $5.32g/h/m^2$ 감소하였다. 대조군의 멜라닌 지수는 시간에 따라 그 값이 유의적으로 증가하였으나, 듀올리고군의 멜라닌 지수는 시간에 따른 유의적 차이가 나타나지 않았다. 또한, 듀올리고군은 대조군에 비하여 주름의 총 넓이, 총 주름의 길이, 주름의 수 및 주름의 깊이가 확연하게 감소하였다(p < 0.05). 듀올리고의 피부개선 기능성 소재로서의 응용 가능성을 확인하였다.

Keywords

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