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A Change of Apparent Diffusion Coefficient in Diffusion Weighted Imaging Applied with Rectangular FOV Technique

확산강조영상 검사 시 rectangular FOV 적용에 따른 ADC 값의 변화

  • Na, Sa-Ra (Department of Radiology, Asan Medical Center) ;
  • Choi, Kwan-Woo (Department of Radiology, Asan Medical Center) ;
  • Koo, No-Hyun (Department of Radiology, Asan Medical Center) ;
  • Yoo, Beong-Gyu (Department of Radiotechnology, Wonkwang Health Science University) ;
  • Son, Soon-Yong (Department of Radiotechnology, Wonkwang Health Science University)
  • 나사라 (서울아산병원 영상의학과) ;
  • 최관우 (서울아산병원 영상의학과) ;
  • 구노현 (서울아산병원 영상의학과) ;
  • 유병규 (원광보건대학교 방사선과) ;
  • 손순룡 (원광보건대학교 방사선과)
  • Received : 2016.10.19
  • Accepted : 2016.11.30
  • Published : 2016.11.30

Abstract

The purpose of this study is to improve the mapping between functional image and conventional image by using rectangular FOV technique. Diffusion weighted imaging which is widely used for stroke was acquired by reducing the FOV and compared each Apparent Diffusion Coefficient(ADC). As a result, there is no significant difference of each ADC value in one-way-anova analysis and post-hoc analysis. Thus, Mismatching problem may be improved by matching the FOV with rectangular FOV technique because there is no difference in ADC values.

본 연구는 MRI를 이용한 기능검사 시 rectangular FOV를 적용하더라도 기능을 정량화한 대표 값은 차이가 없다는 것을 증명함으로써, FOV 불일치로 인해 발생되는 문제점을 개선하고자 하였다. 연구방법은 대표적인 기능 검사로 뇌졸증의 진단에 널리 사용되고 있는 확산강조영상 검사를 이용하여, 주파수부호화 방향의 FOV 변화에 따른 ADC 값의 변화 여부를 비교평가 하였다. 연구결과, 주파수부호화 방향의 FOV가 변화함에 따라 ADC값은 통계적으로 유의한 차이를 보이지 않았으며, 사후분석 결과도 유의수준 0.05에 대한 부집단이 모두 1개 밖에 존재하지 않아 FOV 변화에 따른 ADC 값의 차이가 없음을 알 수 있었다. 결론적으로 MRI를 이용한 기능 영상에서 rectangular FOV를 적용하더라도 기능을 정량화한 대표 값에는 차이가 없으므로, FOV 불일치로 인해 수반되는 공간왜곡이나 mismatching의 문제점을 개선할 수 있다.

Keywords

References

  1. H. Y. Carr, "Steady-state free precession in nuclear magnetic resonance. Physical Review", Vol. 112, No. 5, 1693.
  2. K. P. Pruessmann, M. Weiger, M. B. Scheidegger, P. Boesiger, "SENSE: sensitivity encoding for fast MRI", Magnetic resonance in medicine, Vol. 42, No. 5, pp. 952-962, 1999. https://doi.org/10.1002/(SICI)1522-2594(199911)42:5<952::AID-MRM16>3.0.CO;2-S
  3. K. Setsompop, B. A. Gagoski, J. R. Polimeni, T. Witzel, V. J. Wedeen, L. L. Wald, "Blipped-controlled aliasing in parallel imaging for simultaneous multislice echo planar imaging with reduced g-factor penalty", Magnetic Resonance in Medicine, Vol. 67, No. 5, pp. 1210-1224, 2012. https://doi.org/10.1002/mrm.23097
  4. C. Westbrook, C. K. Roth, "MRI in Practice", John Wiley & Sons", 2011.
  5. R. Turner, D. L. Bihan, "Single-shot diffusion imaging at 2.0 Tesla", Journal of Magnetic Resonance, Vol. 86, No. 3, pp. 445-452, 1990. https://doi.org/10.1016/0022-2364(90)90023-3
  6. M. A. Haider, T. H. Kwast, J. Tanguay, A. J. Evans, A. T. Hashmi, G. Lockwood, J. Trachtenberg, "Combined T2-weighted and diffusion weighted MRI for localization of prostate cancer", American Journal of Roentgenology, Vol. 189, No. 2, pp. 323-328, 2007. https://doi.org/10.2214/AJR.07.2211
  7. M. E. Moseley, J. Kucharczyk, J. Mintorovitch, Y. Cohen, J. Kurhanewicz, N. Derugin, D. Norman, "Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility enhanced MR imaging in cats", American Journal of Neuroradiology, Vol. 11, No. 3, pp. 423-429, 1990.
  8. E. O. Stejskal, J. E. Tanner, "Spin diffusion measurements: spin echoes in the presence of a time-dependent field gradient", The journal of chemical physics, Vol. 42, No. 13, pp. 288-292, 1995
  9. F. N. Wang, T. Y. Huang, F. H. Lin, T. C. Chuang, N. K. Chen, H. W. Chung, K. K. Kwong, "PROPELLER EPI: an MRI technique suitable for diffusion tensor imaging at high field strength with reduced geometric distortions", Magnetic resonance in medicine, Vol. 54, No. 5, pp. 1232-1240, 2005. https://doi.org/10.1002/mrm.20677
  10. H. Tullos, B. Dale, G. Bidwell, E. Perkins, D. Raucher, M. Khan, J. James, "SU-E-I-67: Multi-Shot RESOLVE Compared to Single-Shot EPI Diffusion- Weighted MR Imaging Acquisition Scheme", Medical Physics, Vol. 39, No. 6, pp. 3640-3640, 2012.
  11. F. Donato, D. N. Costa, Q. Yuan, N. M. Rofsky, R. E. Lenkinski, I. Pedrosa, "Geometric Distortion in Diffusion-weighted MR Imaging of the Prostate- Contributing Factors and Strategies for Improvement", Academic radiology, Vol. 21, No. 6, pp. 817-823, 2014. https://doi.org/10.1016/j.acra.2014.02.001
  12. E. U. Saritas, C. H. Cunningham, J. H. Lee, E. T. Han, D. G. Nishimura, "DWI of the spinal cord with reduced FOV single-shot EPI", Magnetic resonance in medicine, Vol. 60, No. 23, pp. 468-473, 2008. https://doi.org/10.1002/mrm.21640

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