Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effects of Tarak, Korean Traditional Fermented Milk, on Proliferation of Immune Cells and Melanin Biosynthesis

전통발효유 타락의 면역세포 증식 및 멜라닌 생성에의 효과 - 연구노트 -

  • Kim, Soyoung (Department of Food and Nutrition, Sungshin Women's University) ;
  • Choi, Yumi (Department of Food and Nutrition, Sungshin Women's University) ;
  • Lee, Heera (Department of Food and Nutrition, Sungshin Women's University) ;
  • Park, Jisoo (Department of Food and Nutrition, Sungshin Women's University) ;
  • Han, Young-Sook (Department of Food and Nutrition, Sungshin Women's University) ;
  • Ko, Seong-Hee (The Graduate School of Cultural Industry, Sungshin Women's University) ;
  • Jang, Sung-Sik (R&BD Center, Korea Yakult Ltd.) ;
  • Kim, Soo-A (R&BD Center, Korea Yakult Ltd.) ;
  • Shim, Jae-Hun (R&BD Center, Korea Yakult Ltd.) ;
  • Yoon, Hyungeun (Department of Food and Nutrition, Sungshin Women's University)
  • 김소영 (성신여자대학교 식품영양학과) ;
  • 최유미 (성신여자대학교 식품영양학과) ;
  • 이희라 (성신여자대학교 식품영양학과) ;
  • 박지수 (성신여자대학교 식품영양학과) ;
  • 한영숙 (성신여자대학교 식품영양학과) ;
  • 고성희 (성신여자대학교 문화산업대학원) ;
  • 장성식 (한국야쿠르트 중앙연구소) ;
  • 김수아 (한국야쿠르트 중앙연구소) ;
  • 심재헌 (한국야쿠르트 중앙연구소) ;
  • 윤현근 (성신여자대학교 식품영양학과)
  • Received : 2015.07.14
  • Accepted : 2015.10.03
  • Published : 2015.11.30
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Abstract

Tarak is a Korean traditional fermented milk product that is fermented by adding rice wine to milk. Tarak was produced with Lactobacillus paracasei ssp. paracasei M13-65-3 isolated from rice wine, and its effects on immune cell proliferation and melanin biosynthesis were investigated. Tarak extract significantly increased proliferation of T lymphocyte Jurkat clone E6-1 cells at concentrations from 10 to $100{\mu}g/mL$. Tarak inhibited activities of tyrosinase and ${\alpha}$-melanocyte-stimulating hormone-induced melanin biosynthesis in mouse skin B16-F10 cells at a concentration of $100{\mu}g/mL$. These results suggest that tarak might have functionalities for enhancing the immune system by increasing immune cell proliferation and regulating melanin biosynthesis.

시판 막걸리에서 분리한 균주(Lactobacillus paracasei ssp. paracasei M13-65-3)로 타락을 제조하였다. M13-65-3균주를 이용하여 제조한 타락 추출물에 의하여 T lymphocyte인 Jurkat 세포의 증식이 촉진되었고 피부세포의 멜라닌 생성이 억제되었다. 본 연구의 결과는 타락이 면역 증강 기능성과 피부색소 조절 기능성을 보유할 가능성을 제시하고 있다.

Keywords

References

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