기공(氣功) 운동이 유방암 절제술 여성의 면역, 맥상파 및 심박변이에 미치는 영향

Effects of Qi Gong Exercise on the Immune Response, Pulse Wave Parameter and Heart Rate Variability(HRV) for Post Mastectomy Women

  • 김이순 (동의대학교 의료보건대학 의료경영학과) ;
  • 이정원 (동의대학교 의료보건대학 의료경영학과) ;
  • 김윤희 (부경대학교 자연과학대학 간호학과) ;
  • 오미정 (영산대학교 보건의료대학 간호학과) ;
  • 김경철 (동의대학교 한의과대학 진단학교실)
  • 투고 : 2015.07.29
  • 심사 : 2015.08.26
  • 발행 : 2015.08.31

초록

Objectives The purposes of this study was to develope a Qi gong exercise that suits characteristics of post mastectomy women, and to evaluate the effect of Qi gong exercise on immune response, blood circulation index, pulse wave parameter and heart rate variability. Methods This study was applied to total 35 post mastectomy women, including 17 for experiment group and 18 for control group. The Qi gong exercise was composed of total 24 times of 90 minutes per each time, twice a week, and 12 weeks and it was conducted by the oriental medicine professor who was an expert of Qi gong exercise. Results 1. Two group comparison revealed that the experimental group had significantly improved immune response(p<.021), HR(beats/min)(p<.001), ESV(ml/beat)(p=.038), ESI($ml/beat/m^2$)(p=.040), ECO (L/min)(p=.019), ECI($L/min/m^2$)(p=.023), ECRI($dyne^*sec/cm$)(p=.015), Left Kwan($div^3$)(p=.021), Right Kwan($div^3$)(p=.038), Mean HRV(cycle/min)(p<.001), SDNN(ms)(p=.043), RMSSD(ms)(p=.040), and TP(log $ms^2$)(p=.039). 2. Two group comparison revealed that the experimental group had significantly decreased ECR ($dyne^*sec^*cm^{-5}$) (p=.034), Left RAI(p=.044), Right RAI(p=.042), and pNN50(%)(p=.038). Conclusions These results from Qi gong exercise program can be used as basic data for development of health promotion program for Post Mastectomy Women.

키워드

참고문헌

  1. 보건복지부 중앙암등록본부 2014년 12월 발표 자료.
  2. Korean Breast Cancer Society. 2013 Breast Cancer Facts & Figures. Korean Breast Cancer Society. (in Korean).
  3. Longman AJ, Braden CJ, Mishel MH. Side-effect burden, psychological adjustment, and life quality in women with breast cancer : pattern of association over time. Oncology Nursing Forum, 1999; 26(5): 909-915.
  4. Issksson G, Feuk B. Morbidity from axillary treatment in breast cancer follow up study in a district hospital. Acta Oncology, 2000; 39(3): 335-336. https://doi.org/10.1080/028418600750013104
  5. Pinto BM, Clark MM, Maruyama NC, Feder SI. Psychological and fitness change associated with exercise participation among woman with breast cancer, Psychooncology 2003; 12: 118-126. https://doi.org/10.1002/pon.618
  6. 채영란. 치료중인 유방암 환자의 신체적 증상과 자연 살해세포 활성도의 관계. 대한기초간호자연과학회지. 2002; 4(2): 69-77.
  7. 김조자, 허혜경, 강덕희, 김보환. 유방암 환자의 스트레스 대응능력 증진을 위한 심리사회적 중재효과. 대한간호학회지. 2006; 36(1): 169-178.
  8. Schmitz KH, Holtzman J, Courneya K, Masse LC, Duval S, Kane R. Controlled physical activity trials in cancer survivors: a systemic review and meta analysis, Cancer Epidemiology Biomarkers Prevention. 2005; 14: 1588-1595. https://doi.org/10.1158/1055-9965.EPI-04-0703
  9. Hoffman-Goetz L. Husted J. Exercise and breast cancer: review and critical analysis of the literature. Canadian Journal of Applied Physiology. 1994; 19(3): 237-252. https://doi.org/10.1139/h94-020
  10. Fairey AS, Courneya KS, Field CJ, Bell GJ, Jones LW, Mackey JR. Randomized controlled trial of exercise and blood immune function in postmenopausal breast cancer survivors. Journal of applied physiology. 2005; 98(4): 1534-1540. https://doi.org/10.1152/japplphysiol.00566.2004
  11. 조현진. 유방절제술 후 운동프로그램의 참여가 면역글로블린과 신체상에 미치는 영향. 전남 : 전남대학교 대학원 석사학위논문. 2003.
  12. 김철우. 태극권 운동이 유방암 수술 환자의 어깨관절 및 심혈관 기능과 면역력 향상에 미치는 영향. 동의대학교 대학원 박사학위논문. 2009.
  13. Lee MS, Chen KW, Sancier KM, Ernst E. Qi gong for cancer treatment: a systemic review of controlled clinical trials. Acta Oncological. 2007; 46(6): 717-722. https://doi.org/10.1080/02841860701261584
  14. Oh BM, Butow P, Mullan B, Clarke S, Beale P, Pavlakis E, Kothe E, Lam L, Rosenthal D. Impact of medical qi gong on quality of life, fatigue, mood and inflammation in cancer patients: a randomized controlled trial, Annals of Oncology. 2010; 21: 608-614. https://doi.org/10.1093/annonc/mdp479
  15. 보건복지부. 2004년도 한방지역보건사업안내. 보건복지부, 2004; 59-64.
  16. 김경철, 김이순, 곽이섭, 이해웅, 이경구. 기공의 한의학적인 가치개발에 대한 연구. 보건복지부. 2009.
  17. Cohen, J. Statistical Power Analysis for the Behavioral Sciences, New York: Academic press. 1988. 28-39.
  18. The State Sport General Administration. Qi gong. The State Sport General Administration. 2003.
  19. Peters C, Lotzerich H, Niemeir B, Schule K, Uhlenbruck G. Exercise, cancer and the immune reponse of monocytes. anticancer Research. 1995; 15(1): 175-179.
  20. Head JF, Elliott RL, McCoy JL. Evaluation of lymphocyte immunity in breast cancer patients. Breast cancer research and treatmen. 1993; 26(1): 77-88. https://doi.org/10.1007/BF00682702
  21. 姜孝信, 李政祜(년도). 氣功學. 一中社. p.80-91.
  22. 김명미. 氣功의 구성원리와 수련효과에 관한 문헌연구. 서울: 명지대학교 대학원 석사학위 논문. 2003.
  23. 김경철, 김이순. 난임 여성의 체질량지수(BMI), 불임기간에 따른 맥파 연구. 한국한의학연구논문집. 2012; 18(2): 139-149.
  24. 김경철, 이정원, 류경호, 강희정. 고령자의 맥상 특성에 대한 맥파 분석적인 연구. 대한한의진단학회지. 2009; 12(2): 1-7.
  25. 서수경. 심박변이도 측정을 통해 살펴본 고혈압과 스트레스와의 연관성. 서울: 한양대학교 대학원 박사학위논문. 2007.
  26. Task Force of the European Society of Cardiology and the North America Society of Pacing and Electro-physiology. Heart Rate Variability: Standard of measurement, physiological interpretation and clinical use. Circulation. 1996; 93(1): 43-65.
  27. 서은영, 이은옥. 활동운동이 보조적 항암화학요법을 받는 유방암 환자들의 피로에 미치는 영향. 성인간호학회지. 1997; 9(3): 437.