Asian Pacific Journal of Cancer Prevention

  • 제16권14호
  • /
  • Pages.5907-5912
  • /
  • 2015
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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Kidney-sparing Management Versus Nephroureterectomy for Upper Tract Urothelial Carcinoma: a Systematic Review and Meta-analysis

  • Luo, You (Institute of Gansu Nephro-Urological Clinical Center, Institute of Urology, Department of Urology, Key Laboratory of Urological Disease of Gansu Province, Lanzhou University Second Hospital) ;
  • She, Dong-Li (Institute of Gansu Nephro-Urological Clinical Center, Institute of Urology, Department of Urology, Key Laboratory of Urological Disease of Gansu Province, Lanzhou University Second Hospital) ;
  • Xiong, Hu (Institute of Gansu Nephro-Urological Clinical Center, Institute of Urology, Department of Urology, Key Laboratory of Urological Disease of Gansu Province, Lanzhou University Second Hospital) ;
  • Fu, Sheng-Jun (Institute of Gansu Nephro-Urological Clinical Center, Institute of Urology, Department of Urology, Key Laboratory of Urological Disease of Gansu Province, Lanzhou University Second Hospital) ;
  • Yang, Li (Institute of Gansu Nephro-Urological Clinical Center, Institute of Urology, Department of Urology, Key Laboratory of Urological Disease of Gansu Province, Lanzhou University Second Hospital)
  • 발행 : 2015.09.02
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Purpose: To evaluate and update evidence for prognostic effects of kidney-sparing (KS) management and nephroureterectomy (NU) for upper tract urothelial carcinomas. Materials and Methods: Pubmed, Embase and the Cochrane Library were retrieved for the identification of comparative studies of kidney-sparing procedure and nephroureterectomy for upper tract urothelial carcinoma prior to December 2014. The data were extracted independently by 2 reviewers and the quality of the included studies was assessed. Review Manager 5.3 and STATA 13 were used to perform the meta-analysis. Results: Twenty-three observational studies including 1,587 KS and 3,996 NU were evaluated. The results of the meta-analysis showed that nephroureterectomy had no significant benefit with regard to intravesical recurrence (IRFS), metastasis (MFS), cancer specific survival (CSS) and overall survival (OS) except the total tumor recurrence (RFS) when compared with kidney sparing management. The respectively pooled outcomes were HR 1.36 (0.69-2.68, P=0.38) for IRFS, 1.09 (0.59-2.01, P=0.78) for MFS, 1.17 (0.77-1.79, P=0.47) for CSS, 1.50 (0.90-2.48, P=0.12) for OS and 1.61 (1.03-2.51, P=0.04) for RFS. Conclusions: On the whole, kidney-sparing management had equivalent prognostic effect on upper tract urothelial carcinoma as the standard nephroureterectomy except in tumor recurrence. However, the results should be interpreted with caution for lack of stage and grade stratification and multi-center randomized controlled trials are still needed to verify our results.

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참고문헌

  1. Bagrodia A, Kuehhas FE, Gayed BA, et al (2013). Comparative analysis of oncologic outcomes of partial ureterectomy vs radical nephroureterectomy in upper tract urothelial carcinoma. Urology, 81, 972-7. https://doi.org/10.1016/j.urology.2012.12.059
  2. Bin X, Roy OP, Ghiraldi E, et al (2012). Impact of tumour location and surgical approach on recurrence-free and cancer-specific survival analysis in patients with ureteric tumours. BJU Int, 110, 514-9. https://doi.org/10.1111/j.1464-410X.2012.11199.x
  3. Bing-bing S, Cheng C, Han-zhong L, et al (2012). Correlation between surgical modality and clinicopathologic characteristics for ureteral transitional cell carcinoma. Clin Transl Oncol, 14, 312-6. https://doi.org/10.1007/s12094-012-0800-8
  4. Boorjian S, Ng C, Munver R, et al (2005). Impact of delay to nephroureterectomy for patients undergoing ureteroscopic biopsy and laser tumor ablation of upper tract transitional cell carcinoma. Urology, 66, 283-7. https://doi.org/10.1016/j.urology.2005.02.022
  5. Chen WJ, Kuo JY, Chen KK, et al (2005). Primary urothelial carcinoma of the ureter: 11-year experience in Taipei veterans general hospital. J Chin Med Assoc, 68, 522-30. https://doi.org/10.1016/S1726-4901(09)70087-5
  6. Colin P, Ouzzane A, Pignot G, et al (2012). Comparison of oncological outcomes after segmental ureterectomy or radical nephroureterectomy in urothelial carcinomas of the upper urinary tract: results from a large French multicentre study. BJU Int, 110, 1134-41. https://doi.org/10.1111/j.1464-410X.2012.10960.x
  7. Cutress ML, Stewart GD, Tudor EC, et al (2013). Endoscopic versus laparoscopic management of noninvasive upper tract urothelial carcinoma: 20-year single center experience. J Urol, 189, 2054-60. https://doi.org/10.1016/j.juro.2012.12.006
  8. Dalpiaz O, Ehrlich G, Quehenberger F, et al (2014). Distal ureterectomy is a safe surgical option in patients with urothelial carcinoma of the distal ureter. Urol Oncol, 32, 1-8. https://doi.org/10.1016/j.urolonc.2013.08.027
  9. Dragicevic D, Djokic M, Pekmezovic T, et al (2009). Comparison of open nephroureterectomy and open conservative management of upper urinary tract transitional cell carcinoma. Urol Int, 82, 335-40. https://doi.org/10.1159/000209368
  10. Fajkovic H, Klatte T, Nagele U, et al (2013). Results and outcomes after endoscopic treatment of upper urinary tract carcinoma: the Austrian experience. World J Urol, 31, 37-44. https://doi.org/10.1007/s00345-012-0948-4
  11. Fukushima H, Saito K, Ishioka J, et al (2014). Equivalent survival and improved preservation of renal function after distal ureterectomy compared with nephroureterectomy in patients with urothelial carcinoma of the distal ureter: a propensity score-matched multicenter study. Int J Urol, 21, 1098-104. https://doi.org/10.1111/iju.12554
  12. Gadzinski AJ, Roberts WW, Faerber GJ, et al (2010). Longterm outcomes of nephroureterectomy versus endoscopic management for upper tract urothelial carcinoma. J Urol, 183, 2148-53. https://doi.org/10.1016/j.juro.2010.02.005
  13. Gadzinski AJ, Roberts WW, Faerber GJ, et al (2012). Long-term outcomes of immediate versus delayed nephroureterectomy for upper tract urothelial carcinoma. J Endourol, 26, 566-73. https://doi.org/10.1089/end.2011.0220
  14. Giannarini G, Schumacher MC, Thalmann GN, et al (2007). Elective management of transitional cell carcinoma of the distal ureter: can kidney-sparing surgery be advised? BJU Int, 100, 264-8. https://doi.org/10.1111/j.1464-410X.2007.06993.x
  15. Grasso M, Fishman AI, Cohen J, et al (2012). Ureteroscopic and extirpative treatment of upper urinary tract urothelial carcinoma: a 15-year comprehensive review of 160 consecutive patients. BJU Int, 110, 1618-26. https://doi.org/10.1111/j.1464-410X.2012.11066.x
  16. Gurbuz C, Youssef RF, Shariat SF, et al (2011). The impact of previous ureteroscopic tumor ablation on oncologic outcomes after radical nephrouretectomy for upper urinary tract urothelial carcinoma. J Endourol, 25, 775-9. https://doi.org/10.1089/end.2010.0396
  17. Hall MC, Womack S, Sagalowsky AI, et al (1998). Prognostic factors, recurrence, and survival in transitional cell carcinoma of the upper urinary tract: a 30-year experience in 252 patients. Urol, 52, 594-601. https://doi.org/10.1016/S0090-4295(98)00295-7
  18. Higgins JPT, Green S (2011). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011] [Online]. The Cochrane Collaboration. Available: www.cochrane-handbook.org.
  19. Hoffman A, Yossepowitch O, Erlich Y, et al (2014). Oncologic results of nephron sparing endoscopic approach for upper tract low grade transitional cell carcinoma in comparison to nephroureterectomy - a case control study. BMC Urol, 14, 97. https://doi.org/10.1186/1471-2490-14-97
  20. Hung SY, Yang WC, Luo HL, et al (2014). Segmental ureterectomy does not compromise the oncologic outcome compared with nephroureterectomy for pure ureter cancer. Int Urol Nephrol, 46, 921-6. https://doi.org/10.1007/s11255-013-0514-z
  21. Ishikawa S, Abe T, Shinohara N, et al (2010). Impact of diagnostic ureteroscopy on intravesical recurrence and survival in patients with urothelial carcinoma of the upper urinary tract. J Urol, 184, 883-7. https://doi.org/10.1016/j.juro.2010.05.027
  22. Jeldres C, Lughezzani G, Sun M, et al (2010). Segmental ureterectomy can safely be performed in patients with transitional cell carcinoma of the ureter. J Urol, 183, 1324-9. https://doi.org/10.1016/j.juro.2009.12.018
  23. Klatte T, Zigeuner RE, Roupret M, et al (2013). 575 Segmental ureterectomy versus radical nephroureterectomy for urothelial cancer of the ureter: A matched-pair analysis. Eur Urol Suppl, 12, 575-6. https://doi.org/10.1016/S1569-9056(13)61058-1
  24. Lehmann J, Suttmann H, Kovac I, et al (2007). Transitional cell carcinoma of the ureter: prognostic factors influencing progression and survival. Eur Urol, 51, 1281-8. https://doi.org/10.1016/j.eururo.2006.11.021
  25. Lucas SM, Svatek RS, Olgin G, et al (2008). Conservative management in selected patients with upper tract urothelial carcinoma compares favourably with early radical surgery. BJU Int, 102, 172-6. https://doi.org/10.1111/j.1464-410X.2008.07535.x
  26. Lughezzani G, Jeldres C, Isbarn H, et al (2009). Nephroureterectomy and segmental ureterectomy in the treatment of invasive upper tract urothelial carcinoma: a population-based study of 2299 patients. Eur J Cancer, 45, 3291-7. https://doi.org/10.1016/j.ejca.2009.06.016
  27. Lughezzani G, Jeldres C, Isbarn H, et al (2010). Temporal stage and grade migration in surgically treated patients with upper tract urothelial carcinoma. BJU Int, 105, 799-804. https://doi.org/10.1111/j.1464-410X.2009.08818.x
  28. Luo HL, Kang CH, Chen YT, et al (2013). Diagnostic ureteroscopy independently correlates with intravesical recurrence after nephroureterectomy for upper urinary tract urothelial carcinoma. Ann Surg Oncol, 20, 3121-6. https://doi.org/10.1245/s10434-013-3000-z
  29. Malcolm JB, Bagrodia A, Derweesh IH, et al (2009). Comparison of rates and risk factors for developing chronic renal insufficiency, proteinuria and metabolic acidosis after radical or partial nephrectomy. BJU Int, 104, 476-81. https://doi.org/10.1111/j.1464-410X.2009.08376.x
  30. Moher D, Liberati A, Tetzlaff J, et al (2009). Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med, 6, 1000097. https://doi.org/10.1371/journal.pmed.1000097
  31. Munoz JJ, Ellison LM (2000). Upper tract urothelial neoplasms: incidence and survival during the last 2 decades. J Urol, 164, 1523-5. https://doi.org/10.1016/S0022-5347(05)67019-X
  32. Nison L, Roupret M, Bozzini G, et al (2013). The oncologic impact of a delay between diagnosis and radical nephroureterectomy due to diagnostic ureteroscopy in upper urinary tract urothelial carcinomas: results from a large collaborative database. World J Urol, 31, 69-76. https://doi.org/10.1007/s00345-012-0959-1
  33. Phillips B, Ball C, Sackett D, et al (2009). Oxford Centre for Evidence-based Medicine Levels of Evidence (March 2009) [Online]. OCEBM Levels of Evidence Working Group. Available: http://www.cebm.net/oxford-centre-evidencebased-medicine-levels-evidence-march-2009/.
  34. Raymundo EM, Lipkin ME, Banez LB, et al (2011). Third prize: the role of endoscopic nephron-sparing surgery in the management of upper tract urothelial carcinoma. J Endourol, 25, 377-84. https://doi.org/10.1089/end.2010.0276
  35. Roupret M, Babjuk M, Comperat E, et al (2013). European guidelines on upper tract urothelial carcinomas: 2013 update. Eur Urol, 63, 1059-71. https://doi.org/10.1016/j.eururo.2013.03.032
  36. Roupret M, Hupertan V, Traxer O, et al (2006). Comparison of open nephroureterectomy and ureteroscopic and percutaneous management of upper urinary tract transitional cell carcinoma. Urol, 67, 1181-7. https://doi.org/10.1016/j.urology.2005.12.034
  37. Seisen T, Granger B, Colin P, et al (2014). A Systematic Review and Meta-analysis of Clinicopathologic Factors Linked to Intravesical Recurrence After Radical Nephroureterectomy to Treat Upper Tract Urothelial Carcinoma. Eur Urol.
  38. Shiraishi K, Eguchi S, Mohri J, et al (2003). Role of ureteroscopic biopsy in the management of upper urinary tract malignancy. Int J Urol, 10, 627-30. https://doi.org/10.1046/j.1442-2042.2003.00721.x
  39. Siegel R, Naishadham D, Jemal A (2013). Cancer statistics, 2013. CA Cancer J Clin, 63, 11-30. https://doi.org/10.3322/caac.21166
  40. Simhan J, Smaldone MC, Egleston BL, et al (2014). Nephronsparing management vs radical nephroureterectomy for low- or moderate-grade, low-stage upper tract urothelial carcinoma. BJU Int, 114, 216-20. https://doi.org/10.1111/bju.12341
  41. Sundi D, Svatek RS, Margulis V, et al (2012). Upper tract urothelial carcinoma: impact of time to surgery. Urol Oncol, 30, 266-72. https://doi.org/10.1016/j.urolonc.2010.04.002
  42. Tierney JF, Stewart LA, Ghersi D, et al (2007). Practical methods for incorporating summary time-to-event data into metaanalysis. Trials, 8, 16-. https://doi.org/10.1186/1745-6215-8-16
  43. Waldert M, Karakiewicz PI, Raman JD, et al (2010). A delay in radical nephroureterectomy can lead to upstaging. BJU Int, 105, 812-7. https://doi.org/10.1111/j.1464-410X.2009.08821.x
  44. Yakoubi R, Colin P, Seisen T, et al (2014). Radical nephroureterectomy versus endoscopic procedures for the treatment of localised upper tract urothelial carcinoma: a meta-analysis and a systematic review of current evidence from comparative studies. Eur J Surg Oncol, 40, 1629-34. https://doi.org/10.1016/j.ejso.2014.06.007

피인용 문헌

  1. Comparison of Radical Nephroureterectomy and Partial Ureterectomy for the Treatment of Upper Tract Urothelial Carcinoma vol.2018, pp.2314-6141, 2018, https://doi.org/10.1155/2018/2793172