Journal of Korea Technical Association of The Pulp and Paper Industry (펄프종이기술)

Korea Technical Association of the Pulp and Paper Industry (한국펄프종이공학회)
권호 표지
DOI QR코드

DOI QR Code

Permeability Control of Cellulose Hydrogel Membrane Using Alginate

알지네이트를 이용한 셀룰로오스 하이드로겔의 투과 특성 제어

  • Jeong, Eunsue (Department of Biosystems and Biomaterials Science and Engineering, College of Agriculture and Life Sciences, Seoul National University) ;
  • Shin, Sungchul (Department of Biosystems and Biomaterials Science and Engineering, College of Agriculture and Life Sciences, Seoul National University) ;
  • Park, Minsung (Department of Biosystems and Biomaterials Science and Engineering, College of Agriculture and Life Sciences, Seoul National University) ;
  • Hyun, Jinho (Center for Food and Bioconvergence, Seoul National University)
  • 정은수 (서울대학교 농업생명과학대학 바이오시스템.소재학부) ;
  • 신성철 (서울대학교 농업생명과학대학 바이오시스템.소재학부) ;
  • 박민성 (서울대학교 농업생명과학대학 바이오시스템.소재학부) ;
  • 현진호 (서울대학교 식품바이오융합연구소)
  • Received : 2015.03.03
  • Accepted : 2015.04.19
  • Published : 2015.04.30
Download PDF
⟨ Previous Next ⟩

Abstract

Natural cellulose hydrogel membrane cannot be directly used for cell encapsulation because it has many large pores on the surface that immune biomolecules are able to penetrate into easily. For the reason, alginate was used for the control of pore size of the cellulose hydrogel membrane. The surface morphology of cellulose/alginate nanocomposite confirmed the successful control of the porosity of the membrane. The permeability of the cellulose/alginate nanocomposite was decreased but mechanical properties were increased compared with the bacterial cellulose membrane. The cellulose/alginate nanocomposite could be used for the functional membrane as a promising biomedical material in the future.

Keywords

References

  1. Lin, C.C. and Anseth, K. S., Cell-cel communication mimicry with poly(ethylene glycol) hydrogels for enhancing $\beta$-cell function, PNAS, 108(16):6380-6385 (2011). https://doi.org/10.1073/pnas.1014026108
  2. Goh, C. H., Heng, P. W. S. and Chan, L. W., Alginate as a useful naturalpolymer for microencapsulation and therapeutic applications, Carbohydrate Polymers, 88:1-12 (2012). https://doi.org/10.1016/j.carbpol.2011.11.012
  3. Hall, K. K., Gattas-Asfura, K. M. and Stabler, C. L., Microencapsulation of islets within alginate/poly (ethylene glycol) gels cross-linked via Staudinger ligation, Acta biomaterialia, 7(2):614-624 (2011). https://doi.org/10.1016/j.actbio.2010.07.016
  4. Tan, W. H. and Takeuchi, S., Monodisperse alginate hydrogel microbeads for cell encapsulation, Advanced Materials, 19(18):2696-2701 (2007). https://doi.org/10.1002/adma.200700433
  5. Jafar Mazumder, M. A., Burke, N. A., Shen, F., Potter, M. A. and Stover, H. D., Core-cross-linked alginate microencapsules for cell encapsulation, Biomacromolecules, 10(6):1365-1373 (2009). https://doi.org/10.1021/bm801330j
  6. Zhang, W., Zhao, S., Rao, W., Snyder, J., Choi, J. K., Wang, J., Khan, I. A., Saleh, N. B., Mohler, P. J., Yu, J., Hund, T. J., Tang, C., and He, X., A novel core-shell microcapsule for encapsulation and 3D culture for embryonic stem cells, Journal of materials chemistry B, 7:1002-1009 (2013).
  7. Sokolnicki, A. M., Fisher, R. J., Harrah, T. P. and Kaplan, D. L., Permeability of bacterial cellulose membranes, Journal of membrane science, 272(1-2): 15-27 (2006). https://doi.org/10.1016/j.memsci.2005.06.065
  8. Li, Y., Qing, S., Zhou, J. and Yang, G., Evaluation of bacterial cellulose/hyaluronan nanocomposite biomaterials, Carbohydrate polymers, 103:496-501 (2014). https://doi.org/10.1016/j.carbpol.2013.12.059
  9. Zaborowaska, M., Bodin, A., Backdahl, H., Popp, J., Goldstein, A. and Gatenholm, P., Microporous bacterial cellulose as a potential scaffold for bone regeneration, Acta biomaterialia, 6(7):2540-2547 (2010). https://doi.org/10.1016/j.actbio.2010.01.004
  10. Yang, C., Gao, C., Wan, Y., Tang, T., Zhang, S. and Dai, K., Preparation and characteriazation of three-dimensional nanostructured macroporous bacterial cellulose/ agarose scaffold for tissue engineering, Journal of porous materials, 18(5):545-552 (2011). https://doi.org/10.1007/s10934-010-9407-z
  11. Gao, C., Wan, Y., Yang, C., Dai, K., Tang, T., Luo, H. and Wang, J., Preparation and characterization of bacterial cellulose sponge with hierarchical pore structure as tissue engineering scaffold, Journal of porous materials, 18(2):139-145 (2011). https://doi.org/10.1007/s10934-010-9364-6
  12. Kang, A., Park, J., Jeong, G. S. and Lee, S. H., Cell encapsulation via microtechnologies, Biomaterials, 35(9): 2651-2663 (2014). https://doi.org/10.1016/j.biomaterials.2013.12.073