Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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A New Sesterterpene from the Korean Sarcotragus sp. Sponge

  • Woo, Jung-Kyun (Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
  • Jeon, Ju-eun (Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
  • Kim, Bora (Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
  • Sim, Chung J. (Department of Biological Science, College of Life Science and Nano Technology, Hannam University) ;
  • Oh, Dong-Chan (Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
  • Oh, Ki-Bong (Department of Agricultural Biotechnology, College of Agriculture and Life Science, Seoul National University) ;
  • Shin, Jongheon (Natural Products Research Institute, College of Pharmacy, Seoul National University)
  • Received : 2015.06.30
  • Accepted : 2015.08.22
  • Published : 2015.12.31
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Abstract

Sarcotragin C (1), a new sesterterpene metabolite was isolated from a Sarcotragus sp. sponge collected from Chuja Island, Korea. On the basis of the combined spectroscopic analyses, the structure of this compound was determined to be a linear norsesterterpene containing a leucine-derived ${\gamma}-lactam$ moiety. This compound exhibited moderate cytotoxicity against K562 and A549 cell-lines.

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References

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Cited by

  1. Marine natural products vol.34, pp.3, 2015, https://doi.org/10.1039/c6np00124f
  2. Sesterterpenoids: chemistry, biology, and biosynthesis vol.38, pp.7, 2015, https://doi.org/10.1039/d0np00070a