DOI QR코드

DOI QR Code

Titanium surface modification by using microwave-induced argon plasma in various conditions to enhance osteoblast biocompatibility

  • Seon, Gyeung Mi (Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine) ;
  • Seo, Hyok Jin (Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine) ;
  • Kwon, Soon Young (Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine) ;
  • Lee, Mi Hee (Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine) ;
  • Kwon, Byeong-Ju (Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine) ;
  • Kim, Min Sung (Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine) ;
  • Koo, Min-Ah (Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine) ;
  • Park, Bong Joo (Department of Electrical and Biological Physics and Plasma Bioscience Research Center, Kwangwoon University) ;
  • Park, Jong-Chul (Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine)
  • 투고 : 2014.12.01
  • 심사 : 2015.04.11
  • 발행 : 2015.06.30

초록

Background: Titanium is a well proven implantable material especially for osseointegratable implants by its biocompatibility and anti-corrosive surface properties. Surface characteristics of the implant play an important role for the evolution of bone tissue of the recipient site. Among the various surface modification methods, plasma treatment is one of the promising methods for enhance biocompatibility. We made microwave-induced argon plasma at atmospheric pressure to improve in titanium surface biocompatibility. Results: Various states of emission spectra from excited species-argon, nitrogen atoms and oxygen atoms were observed. The electron energy band structures are the unique characteristics of atoms and functional groups. Microwave-induced argon plasma treatment changed the titanium surface to be very hydrophilic especially on the 5 s short treatment and 30 s, 90 s long treatment samples that detected by contact angle measurement. MC3T3-E1 attachment and proliferation assay significantly increased in 5 s at short treatment, 30 s, and 90 s at long treatment after 5 days incubation. Conclusions: Result indicated that microwave-induce argon plasma treatment would be an effective method to modify titanium surface for enhancing cell-material interactions.

키워드

과제정보

연구 과제 주관 기관 : ministry for health & welfare

참고문헌

  1. Branemark PI, Hansonn BO, Adell R, Breine U, Lindstrom J, Hallen O, et al. Osseointegrated titanium implants in the treatment of the edentulous jaw. Scand J Plast Reconstr Surg. 1977;11:171-5.
  2. Albrektsson T, Branemark PI, Hanson HA, Lindstrom J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone anchorage in man. Acta Orthop Scand. 1981;52:155-70. https://doi.org/10.3109/17453678108991776
  3. Liu X, Chu PK, Ding C. Surface modification of titanium, titanium alloys, and related materials for biomedical applications. Mater Sci Eng R. 2004;47:49-121. https://doi.org/10.1016/j.mser.2004.11.001
  4. Molenberg A, Schwarz F, Herten M, Berner S, de Wild M, Wieland M. Improved osseointegration of a novel, hydrophilic Ti surface-a review. Mat-wiss u Werkstofftech. 2009;40:31-5. https://doi.org/10.1002/mawe.200800410
  5. Schliephake H, Scharnweber D. Chemical and biological functionalization of titanium for dental implants. J Mater Chem. 2008;18:2404-14. https://doi.org/10.1039/b715355b
  6. Botticelli D, Berglundh T, Buser D, Lindhe J. The jumping distance revisited: an experimental study in the dog. Clin Oral Implant Res. 2003;14:35-42. https://doi.org/10.1034/j.1600-0501.2003.140105.x
  7. Rosales-Leala JI, Rodríguez-Valverdeb MA. Effect of roughness, wettability and morphology of engineered titanium surfaces on osteoblast-like cell adhesion. Colloids and Surfaces A: Physicochem Eng Aspects. 2010;365:222-9. https://doi.org/10.1016/j.colsurfa.2009.12.017
  8. Han IH, Kwon BJ, Vagaska B, Kim BJ, Kang JK, Lee MH, et al. Nitrogen grafting onto polycarprolactone by a simple surface modification with atmospheric pressure glow discharge (Ar-APGD) and promoted neonatal human fibroblast growth. Macromol Res. 2011;19(11):1134-41. https://doi.org/10.1007/s13233-011-1108-1
  9. Park BJ, Lee DH, Park JC. Sterilization using a microwave-induced argon plasma system at atmospheric pressure. Phys Plasmas. 2003;10:4539-44. https://doi.org/10.1063/1.1613655
  10. Park JC, Park BJ, Han DW, Lee DH, Lee IS, Hyun SO, et al. Fungal sterilization using microwave-induced argon plasma at atmospheric pressure. J Microbiol Biotechnol. 2004;14(1):188-92.
  11. Lee KY, Park BJ, Lee DH, Lee IS, Hyun SO, Chung KH, et al. Sterilization of Escherichia coli and MRSA using microwave-induced argon plasma at atmospheric pressure. Surf Coat Tech. 2005;193:35-8. https://doi.org/10.1016/j.surfcoat.2004.07.034
  12. Park BJ, Takatori K, S-Konishi Y, Kim IH, Lee MH, Han DW, et al. Degradation of mycotoxins using microwave-induced argon plasma at atmospheric pressure. Surf Coat Tech. 2007;201:5733-7. https://doi.org/10.1016/j.surfcoat.2006.07.092
  13. Ryu GH, Yang WS, Roh HW, Lee IS, Kim JK, Lee GH, et al. Plasma surface modification of poly (D, L-lactic-co-glycolic acid) (65/35) film for tissue engineering. Surf Coat Tech. 2005;193:60-4. https://doi.org/10.1016/j.surfcoat.2004.07.062
  14. Lim HR, Baek HS, Lee MH, Woo YI, Han DW, Han MH, et al. Surface modification for enhancing behaviors of vascular endothelial cells onto polyurethane films by microwave-induced argon plasma. Surf Coat Tech. 2008;202:5768-72. https://doi.org/10.1016/j.surfcoat.2008.06.115
  15. Baek HS, Park YH, Ki CS, Park JC, Rah DK. Enhanced chondrogenic responses of articular chondrocytes onto porous silk fibroin scaffolds treated with microwave-induced argon plasma. Surf Coat Tech. 2008;202:5794-7. https://doi.org/10.1016/j.surfcoat.2008.06.154
  16. Bachmann J, Ellies A, Hartge KH. Development and application of a new sessile drop contact angle method to assess soil water repellency. J Hydrol. 2000;231-232:66-75. https://doi.org/10.1016/S0022-1694(00)00184-0
  17. Van Oss CJ, Giese Jr RF, Good RJ. Re-evaluation of the surface tension components and parameters of polyacetylene from contact angles of liquids. Langmuir. 1990;6:1711-3. https://doi.org/10.1021/la00101a017
  18. Vandrovcova M, Vacik J, Svorcik V, Slepicka P, Kasalkova N, Vorlicek V, et al. Fullerene C60 and hybrid C60/Ti films as substrates for adhesion and growth of bone cells. Phys Stat Sol (a). 2008;205(9):2252-61. https://doi.org/10.1002/pssa.200879730
  19. Han IH, Barbora V, Seo HJ, Kang JK, Kwon BJ, Lee MH, et al. Promoted cell and material interaction on atmospheric pressure plasma treated titanium. Appl Surf Sci. 2012;258:4718-23. https://doi.org/10.1016/j.apsusc.2012.01.065
  20. Anand V, Gowravaram MR. On the purity of atmospheric glow-discharge plasma. IEEE Trans Plasma Sci. 2009;37:1811-6. https://doi.org/10.1109/TPS.2009.2025949
  21. Takahashi T, Ruan JZ, Kubota S, Shiraishi F. Electron thermalization in argon-nitrogen gas mixture excited by 252Cf fission fragments. Phys Rev A. 1982;25:2820-3. https://doi.org/10.1103/PhysRevA.25.2820
  22. Sun WT, Li G, Li HP, Bao CY, Wang HB, Zeng S, et al. Characteristics of atmospheric-pressure, radio-frequency glow discharges operated with argon added ethanol. J Appl Phys. 2007;101:123302. https://doi.org/10.1063/1.2748430
  23. Huang C, Yu QS, Hsieh F-H, Duan YX. Bacterial deactivation using a low temperature argon atmospheric plasma brush with oxygen addition. Plasma Process Polym. 2007;4:77-87. https://doi.org/10.1002/ppap.200600077
  24. Shen H, Xixue H, Yang F, Bei J, Wang S. Combining oxygen plasma treatment with anchorage of cationized gelatin for enhancing cell affinity of poly (lactide-co-glycolide). J Biomaterials. 2007;28(29):4219-30. https://doi.org/10.1016/j.biomaterials.2007.06.004
  25. Davies JE. Understanding peri-implant endosseous healing. J Dent Educ. 2003;67(8):932-49.
  26. Han IH, Barbora V, Park BJ, Lee MH, Lee SJ, Park JC. Selective fibronectin adsorption against albumin and enhanced stem cell attachment on helium atmospheric pressure glow discharge treated titanium. J Appl Phys. 2011;109:124701-6. https://doi.org/10.1063/1.3599885

피인용 문헌

  1. Effect of anodization and alkali-heat treatment on the bioactivity of titanium implant material (an in vitro study) vol.6, pp.3, 2015, https://doi.org/10.4103/2231-0762.183107
  2. Nanostructured β-type titanium alloy fabricated by ultrasonic nanocrystal surface modification vol.39, pp.None, 2017, https://doi.org/10.1016/j.ultsonch.2017.03.061
  3. Human Osteoblast Cell Behaviour on Titanium Discs Treated with Argon Plasma vol.12, pp.11, 2015, https://doi.org/10.3390/ma12111735
  4. Cold atmospheric plasma as an interface biotechnology for enhancing surgical implants vol.41, pp.3, 2015, https://doi.org/10.1080/07388551.2020.1853671
  5. Human osteoblast and fibroblast response to oral implant biomaterials functionalized with non-thermal oxygen plasma vol.11, pp.1, 2021, https://doi.org/10.1038/s41598-021-96526-x