KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Bioactivities of Fermented Rhynchosia nulubilis in Dietary Obese Rats

유도비만 흰쥐에서 발효 서목태가 미치는 생리활성

  • Bae, Gui-jeong (Department of Pharmaceutical Engineering and College of Medical Life Science, Silla University) ;
  • Ha, Bae-jin (Department of Pharmaceutical Engineering and College of Medical Life Science, Silla University)
  • 배귀정 (신라대학교 의생명과학대학 생명공학과) ;
  • 하배진 (신라대학교 의생명과학대학 생명공학과)
  • Received : 2015.11.02
  • Accepted : 2015.12.24
  • Published : 2015.12.27
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Abstract

This study was to examine the lipid metabolism of fermented Rhynchosia nulubilis (FRN) in obese rats. The abnormal content of blood lipids often results in metabolic diseases, such as obesity and hyperlipidemia. Seven weeks female Sprague-Dawley rats were divided into four groups and fed high fat diets for 44 days. Also FRN was administered orally for 44 days at 7.5 ml/kg of body weight of rats. The effects of the lipid metabolism were evaluated by total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), glutamic pyruvate transaminase (GPT) and glutamic oxalacetic transaminase (GOT) levels in sera. The levels of TC, TG, LDL and GPT in FRN-treated groups were lower than those in obese groups. While HDL levels were significantly increased. These results demonstrated that FRN had improving effects of lipid metabolism in the obese rats, suggesting that FRN would be used as an ingredient of the useful functional products.

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References

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