대한임상검사과학회지 (Korean Journal of Clinical Laboratory Science)

  • 제47권4호
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  • Pages.225-229
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  • 2015
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  • 1738-3544(pISSN)
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  • 2288-1662(eISSN)
대한임상검사과학회 (Korean Society for Clinical Laboratory Science)
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뇌전증 EEG결과와 CBC결과의 관계연구

A Study on the Relationship between CBC and EEG for Epilepsy Patients

  • 조윤경 (동남보건대학교 임상병리과) ;
  • 성현호 (동남보건대학교 임상병리과) ;
  • 채경민 (서울대학교 신경과)
  • Jo, Yoon-kyung (Department of Clinical Laboratory Science, Dongnam Health University) ;
  • Sung, Hyun-Ho (Department of Clinical Laboratory Science, Dongnam Health University) ;
  • Chae, Kyoung-Min (Department of Neurology, Seoul National University Hospital)
  • 투고 : 2015.10.14
  • 심사 : 2015.11.02
  • 발행 : 2015.12.30
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⟨ 이전 논문 다음 논문 ⟩

초록

뇌전증은 반복적으로 발작이 발생하는 질환으로, 뇌파검사가 가장 객관적이고 유용한 검사이다. 본 연구의 대상자는 2014년 서울대학교 병원에서 뇌전증 확진판정을 받고 뇌파 검사를 받은 환자를 대상으로 연구목적에 동의한 244명을 대상으로 하였다. 이 중 뇌파 검사결과에 따라 성별과 연령에 상관없이 정상그룹 122명, 비정상그룹 122명을 대상으로 뇌파소견과 혈구산정검사와의 상관관계를 알아보고자 하였다. 이번 연구에서 분석된 뇌파 측정결과와 혈구산정검사 결과와의 유의한 상관관계는 WBC, RBC, neutrophil, lymphocyte로 4항목이었다. WBC (p<0.05)와 neutrophil (p<0.01)은 양의 관계였으며, RBC (p<0.05)와 Lymphocyte (p<0.01)는 음의 관계로 나타났다. 이 논문의 한계점은 항뇌전증 치료제의 종류에 따른 혈구산정 검사결과를 분석하지 못한 것이다. 하지만 동일한 질환에 따른 뇌파결과를 중심으로 분석한 결과는 의미가 있다. 그러므로 이러한 부분은 향후 더욱 많은 데이터를 통계적으로 분석해야 할 필요성이 있다고 생각된다.

Epilepsy is a disorder that causes recurring seizures, and the most objective and useful test for detecting epilepsy is the electroencephalogram (EEG). The subjects of this study are 244 patients who received an EEG after being diagnosed with epilepsy at Seoul National University Hospital in 2014, and who have agreed to the purpose of the study. Based on the EEG results, subjects were divided into normal and abnormal groups with 122 subjects in each group, regardless of their gender and age, to investigate the correlation of EEG and complete blood cell count (CBC) test results. The four significant categories that displayed significant correlation between EEG results and CBC hematological measurements in this study were the white blood cell (WBC), red blood cell (RBC), neutrophil, and lymphocyte tests. The WBC (p<0.05) and neutrophil (p<0.01) showed a positive correlation with EEG results, while RBC (p<0.05) and lymphocyte (p<0.01) showed a negative correlation. One of the limitations of this study is that it is lacking the blood test result analysis according to the types of anti-epilepsy medicine. However, the analysis of EEG results by the same disease has significant meaning. Therefore, further studies are needed to statistically analyze more data in the future.

키워드

참고문헌

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