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A Case Report of Long-term Acupuncture Treatment in Bortezomib Induced Peripheral Neuropathy

보르테조밉으로 유발된 말초신경병증에 대한 장기간의 침치료 증례 보고

  • Kim, So Yeon (School of Korean Medicine, Pusan National University) ;
  • Choi, Jun Yong (School of Korean Medicine, Pusan National University) ;
  • Yun, Young Ju (School of Korean Medicine, Pusan National University) ;
  • Park, Seong Ha (School of Korean Medicine, Pusan National University) ;
  • Han, Chang Woo (School of Korean Medicine, Pusan National University)
  • 김소연 (부산대학교 한의학전문대학원) ;
  • 최준용 (부산대학교 한의학전문대학원) ;
  • 윤영주 (부산대학교 한의학전문대학원) ;
  • 박성하 (부산대학교 한의학전문대학원) ;
  • 한창우 (부산대학교 한의학전문대학원)
  • Received : 2015.10.29
  • Accepted : 2015.11.30
  • Published : 2015.12.27

Abstract

Objectives : We present a successful administration of acupuncture in alleviating persistant peripheral neuropathy due to bortezomib, a potent therapeutic agent of mutlple myeloma. Methods : A patient, experiencing numbness, coldness, tingling and weakness in her feet and hands after bortezomib treatment, was administered acupuncture for 32 weeks, 3 times/week for first 4 weeks and 2 times/week the last 28 weeks, in bilateral acupuncture points, ST36, ST40, EX-LE10, LI11, TE5, and EX-UE9. Responses were assessed at the end of every 4 weeks with Eastern Cooperative Oncology Group(ECOG) grading system, National Cancer Institute - Common Toxicity Criteria(NCIC-CTC) v4.0, Numeric Rating Scale(NRS) 0-10, and Neuropathy Pain Scale (NPS). Results : ECOG was improved from 2 to 1, NCIC-CTC from 2 to 1, NRS from 8 to 1, and NPS from 41 to 5 through 32 weeks of acupuncture treatment. Conclusions : It is conceivable that acupuncture can be a help to relieve bortezomib induced peripheral neuropathy.

Keywords

References

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