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Preparation and Antimicrobial of Zinc Calcium Alginate Films according to Concentration

농도에 따른 알긴산 아연칼슘 필름의 제조 및 항균성

  • Seo, Hye-Jin (Department of Advanced Organic Materials, Yeungnam University) ;
  • Jun, So-Yoon (Department of Advanced Organic Materials, Yeungnam University) ;
  • Lee, Woo-Seung (Department of Advanced Organic Materials, Yeungnam University) ;
  • Park, Jae-Hoon (Department of Advanced Organic Materials, Yeungnam University) ;
  • Son, Tae-Won (Department of Nano, Medical & Polymer Materials, Yeungnam University)
  • 서혜진 (영남대학교 유기신소재공학과) ;
  • 전소윤 (영남대학교 유기신소재공학과) ;
  • 이우승 (영남대학교 유기신소재공학과) ;
  • 박재훈 (영남대학교 유기신소재공학과) ;
  • 손태원 (영남대학교 나노메디컬유기재료공학과)
  • Received : 2014.02.03
  • Accepted : 2014.03.28
  • Published : 2014.09.25

Abstract

Composite films of zinc calcium alginate were prepared by a film maker from 7 wt% sodium alginate solution and then they solidified into 3, 5 wt% content $ZnCl_2$, $CaCl_2$ solution followed by washing and drying at room temperature. The characteristics were measured with several methods (antimicrobial activity, water solubility, swelling ratio and viscosity, SEM, EDS) and the film properties were investigated. Composite films of zinc calcium alginate showed an increase in the water resistance by increasing $ZnCl_2$ and $CaCl_2$ content and the antimicrobial test showed that the calcium alginate as well as zinc alginate films result in excellent antimicrobial activity in the two strains, Staphylococcus and Escherichia coli. The results show the possible improvement of the physical properties of composite films.

7 wt% alginate를 용액상태로 제조한 후 필름 메이커를 이용하여 필름 형태로 만든 후 3, 5 wt%의 $ZnCl_2$, $CaCl_2$ 수용액에 필름을 고화시킨 후 수세하여 상온에서 건조시켜 zinc calcium alginate 복합필름을 제조하였다. 필름의 특성을 조사하기 위하여 항균성, 수용해도, 팽윤도 및 점도, SEM, EDS 분석 등을 측정하였다. Zinc calcium alginate 복합필름은 $ZnCl_2$, $CaCl_2$ 함량이 증가할수록 용해저항성은 증가하였으며, 항균성 시험 결과, zinc alginate 필름뿐만 아니라 calcium alginate 필름에서도 두 균주(포도상구균, 대장균) 모두 우수한 항균력을 확인하였으며, 본 연구를 통해 복합필름의 물성개선의 가능성을 확인하였다.

Keywords

Acknowledgement

Supported by : 영남대학교

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