The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Hypoglycemic Effects of Boiled rice made from Unpolished rice, Job' tear, and Extract From Medicinal Herbs Mixture on Diabetic Rat

당뇨 쥐에 대한 한약재복합추출물로 만든 현미율무밥의 혈당강하 효과

  • Lee, Hyeon-Sun (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University) ;
  • Kong, Hyun-Joo (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University) ;
  • Lee, Eon-Hee (Department of Food and Nutrition, Graduate School, Yeungnam University) ;
  • Hwang, Su-Jung (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University) ;
  • Jung, Hyeon-A (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University) ;
  • Kim, Mi-Lim (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University) ;
  • Choi, Eun-Mi (Department of Food Science and Nutrition, Graduate School, Kyungpook National University) ;
  • Jang, Joung-Hyeon (Division of Cosmetology, Dong-Eui Institute of Technology) ;
  • Yang, Kyung-Mi (Faculty of Herbal Food Cooking & Nutrition, Daegu Haany University)
  • 이현순 (대구한의대학교 한방식품조리영양학부) ;
  • 공현주 (대구한의대학교 한방식품조리영양학부) ;
  • 이언희 (영남대학교 대학원 식품영양학과) ;
  • 황수정 (대구한의대학교 한방식품조리영양학부) ;
  • 정현아 (대구한의대학교 한방식품조리영양학부) ;
  • 김미림 (대구한의대학교 한방식품조리영양학부) ;
  • 최은미 (경북대학교 대학원 식품영양학과) ;
  • 장정현 (부산동의과학대학교 미용계열) ;
  • 양경미 (대구한의대학교 한방식품조리영양학부)
  • Received : 2014.04.25
  • Accepted : 2014.05.26
  • Published : 2014.05.30
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Abstract

Objectives : The purpose of this study was to evaluate boiled rice made from unpolished rice, Job's Tears, and extract from medicinal herbs mixture (HGMCJE) for hypoglycemic effect on STZ-induced diabetic rats. Methods : In the response of glucose tolerance, control and diabetic rats groups was intubated with glucose and HGMCJE. Furthermore, boiled 100% polished rice (P rice), boiled unpolished rice mixed with white rice and Job's tears (polished rice:unpolished rice:Job's tears=60:25:15, UPJ-rice), and UPJ rice made from HGMCJE (HUPJ-rice) were intubated to control and diabetic rats groups, respectively. Then, blood glucose concentration, incremental blood glucose, and area under the curve (${\Delta}AUC$) were analyzed in every experimental groups, and these data were used to evaluate glycemic response. Results : When glucose and p rice were intubated in control and diabetic rats, blood glucose concentration, incremental blood glucose, and incremental response ${\Delta}AUC$ of diabetic groups were significantly increase than control groups. But administraion of a single dose of extract from medicinal herbs mixture and HUPJ-rice in control and diabetic rats inhibited the remarkable increase the level of postprandial blood and ${\Delta}AUC$ at 60, 90, and 120 min Conclusions : These results indicate that when intubation of glucose and P rice were out of control on postprandial glycemic response in diabetic rats. But postprandial glycemic response was well-modulated by administrating a single oral dose of HGMCJE and HUPJ-rice. Therefore, HGMCJE can be developed as an effective hypoglycemic agent.

Keywords

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