Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Lycorine: A Potential Broad-Spectrum Agent Against Crop Pathogenic Fungi

  • Shen, Jin-Wen (College of Life Sciences, Henan Agricultural University) ;
  • Ruan, Yuan (College of Agronomy, Henan Agricultural University) ;
  • Ren, Wei (College of Agronomy, Henan Agricultural University) ;
  • Ma, Bing-Ji (College of Agronomy, Henan Agricultural University) ;
  • Wang, Xiao-Long (College of Agronomy, Henan Agricultural University) ;
  • Zheng, Chun-Feng (College of Agronomy, Henan Agricultural University)
  • Received : 2013.10.17
  • Accepted : 2013.12.13
  • Published : 2014.03.28
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Abstract

A screening test showed that lycorine exhibited significant antifungal activity against 24 pathogenic crop fungi at concentrations of 500 ${\mu}g/ml$ and 100 ${\mu}g/ml$, respectively. Fusarium graminearum was selected for antifungal mechanism studies by observing its mycelial morphology and investigating the variations in its conductivity. In addition, the substance absorption and metabolism of F. graminearum were explored. The mechanism was revealed as being one by which lycorine destroyed the cellular membrane and further influenced substance absorption and cell metabolism.

Keywords

References

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