한국정밀공학회지 (Journal of the Korean Society for Precision Engineering)

  • 제31권5호
  • /
  • Pages.375-380
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  • 2014
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  • 1225-9071(pISSN)
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  • 2287-8769(eISSN)
한국정밀공학회 (Korean Society for Precision Engineering)
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골육세포 성장 촉진을 위한 스마트 써피스 텍스처링 임플란트 스템 제작 기술

Smart Surface Texturing Implant Stem for Enhancement of Osteoblast Cell Biocompatibility

  • 김경한 (한국기계연구원 광응용기계연구실) ;
  • 이제훈 (한국기계연구원 광응용기계연구실) ;
  • 박종권 (한국기계연구원 초정밀시스템연구실) ;
  • 진석원 (한국기계연구원 광응용기계연구실) ;
  • 최완해 (한국 알엠아이) ;
  • 이홍진 (중앙대학교 식품공학과)
  • 투고 : 2014.03.25
  • 심사 : 2014.04.15
  • 발행 : 2014.05.01
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초록

To enhance biocompatibility between the orthopedic implant stem and obsteoblast cells, bone-forming cells, micro-size holes are patterned in Ti plate surface. Initially, the house built laser power stabilization system is applied to the laser micro patterning machine to convince repeatable result. Various pulse widths are irradiated Ti plate and relationship between diameters of patterned holes and pulsed width is derived. Effect of multi pulse is observed and optimal pulse number is considered to avoid heat affected zone. After MG-63 osbeoblast cells are cultured, micro patterned Ti plates are compared with control plates. In SEM image, cells are well aligned and aggregation is observed in both 60, and $100{\mu}m$ patterned plates. Finally, free form surface stem model is prepared to test micro hole patterning.

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참고문헌

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