환경생물 (Korean Journal of Environmental Biology)

  • 제32권1호
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  • Pages.1-15
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  • 2014
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  • 1226-9999(pISSN)
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  • 2287-7851(eISSN)
한국환경생물학회 (Korean Society of Environmental Biology)
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Azole계열 항곰팡이 물질의 양서류 독성: 총설

Effects of Azole Fungicide on Amphibian: Review

  • 박찬진 (한양대학교 자연과학대학 생명과학과) ;
  • 박용아 (한양대학교 자연과학대학 생명과학과) ;
  • 옥승석 (한양대학교 자연과학대학 생명과학과) ;
  • 계명찬 (한양대학교 자연과학대학 생명과학과)
  • Park, Chan Jin (Department of Life Science, College of Natural Sciences, Hanyang University) ;
  • Park, Yong Ah (Department of Life Science, College of Natural Sciences, Hanyang University) ;
  • Ok, Seung Seok (Department of Life Science, College of Natural Sciences, Hanyang University) ;
  • Gye, Myung Chan (Department of Life Science, College of Natural Sciences, Hanyang University)
  • 투고 : 2014.02.18
  • 심사 : 2014.03.11
  • 발행 : 2014.03.31
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초록

양서류는 육상과 수상생태계를 연결하는 먹이사슬의 연결자로 진화적 생태적 지이를 갖는다. 양서류의 배아와 유생은 모체와 독립되어 수환경 내에서 초기발생 및 성장하기 때문에 수환경에 존재하는 다양한 화학물질에 직접적으로 노출될 수 있다. Azole계열 항곰팡이제는 농업 및 의료용으로 널리 사용되는 화학물질로서 농지, 하수처리장 등으로 부터 수계로 유입된다. 최근, 양서류에서 이러한 azole계 물질에 의한 기형유발, 내분비계장애 효과가 증가하고 있다. 본 소고에서는 azole계 물질의 양서류 독성을 파악하고 azole계 물질의 안전한 이용을 위한 가이드라인을 제공하고자 azole계열에 속하는 imidazole, triazole, thiazole, oxazole, pyrazole 항곰팡이 물질이 양서류의 발생, 분화, 생식 등에 미치는 영향에 대해 최근까지의 연구결과를 정리하였다.

Amphibians play a pivotal role in the ecosystem as a mediator between aquatic and terrestrial environment. Currently they are directly exposed to a variety of chemicals in the aquatic environment throughout their life cycle. Azole fungicides have been widely used in medical applications and agricultural activities. The direct exposure of azole fungicides causes an alarming situation for various ecosystem. Recently, teratogenesis and endocrine disruption by azole fungicides have been reported in amphibians. In an effort to provide the current information for amphibian toxicity of azole fungicides and to make the guidelines for safe usage of azole-based materials, the effects of azole fungicides including imidazole, triazole, thiazole, oxazole, and pyrazoleon on early development, differentiation and reproduction of amphibians were reviewed.

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