참고문헌
- Burnstock G. Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev. 2007;87:659-797. https://doi.org/10.1152/physrev.00043.2006
- Collier HO, James, GW, Schneider C. Antagonism by aspirin and fenamates of bronchoconstriction and nociception induced by adenosine-5'-triphosphate. Nature 1966;212:411-412. https://doi.org/10.1038/212411a0
- Hamilton SG, Warburton J, Bhattacharjee A, Ward J, McMahon SB. ATP in human skin elicits a dose-related pain response which is potentiated under conditions of hyperalgesia. Brain 2000;123:1238-1246. https://doi.org/10.1093/brain/123.6.1238
- Abbracchio MP, Burnstock G. Purinoceptors: are there families of P2X and P2Y purinoceptors? Pharmacol Ther. 1994;64:445-475. https://doi.org/10.1016/0163-7258(94)00048-4
- Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev. 1998;50:413-492.
- Chizh BA, Illes P. P2X receptors and nociception. Pharmacol Rev. 2001;53:553-568.
- Dunn PM, Zhong Y, Burnstock G. P2X receptors in peripheral neurons. Prog Neurobiol. 2001;65:107-134. https://doi.org/10.1016/S0301-0082(01)00005-3
- Inoue K. P2 receptors and chronic pain. Purinergic Signal 2007;3:135-144. https://doi.org/10.1007/s11302-006-9045-8
- Bardoni R, Goldstein PA, Lee CJ, Gu JG, MacDermott A. ATP P2X receptors mediate fast synaptic transmission in the dorsal horn of the rat spinal cord. J Neurosci. 1997;17:5297-5304.
- Dubyak GR, el-Moatassim C. Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol. 1993;265:C577-606. https://doi.org/10.1152/ajpcell.1993.265.3.C577
- Khakh BS, Henderson G. ATP receptor-mediated enhancement of fast excitatory neurotransmitter release in the brain. Mol Pharmacol. 1998;54:372-378. https://doi.org/10.1124/mol.54.2.372
- Chen M, Gu JG. A P2X receptor-mediated nociceptive afferent pathsay to lamina I of the spinal cord. Mol Pain 2005;1:4. https://doi.org/10.1186/1744-8069-1-4
- Le KT, Villeneuve P, Ramjaun AR, McPherson PS, Beaudet A, Seguela P. Sensory presynaptic and widespread somatodendritic immunolocalization of central ionotropic P2X ATP receptors. Neuroscience 1998;83:177-190. https://doi.org/10.1016/S0306-4522(97)00365-5
- North RA. Molecular physiology of P2X receptors. Physiol Rev. 2002;82:1013-1067. https://doi.org/10.1152/physrev.00015.2002
- Burnstock G. Purinergic receptors and pain. Curr Pharm Des. 2009;1717-1735.
- Fukuhara N, Imai Y, Sakakibara A, Morita K, Kitayama S, Tanne K, Dohi T. Regulation of development of allodynia by intrathecally administered P2 purinoceptor agonists and antagonists in mice. Neurosci Lett. 2000;292:25-28. https://doi.org/10.1016/S0304-3940(00)01427-0
- Tsuda M, Ueno S, Inoue K. In vivo pathway of thermal hyperalgesia by intrathecal administration of alpha, beta-methylene ATP in mouse spinal cord: involvement of the glutamate-NMDA receptor system. Br J Pharmacol. 1999;127:449-456. https://doi.org/10.1038/sj.bjp.0702582
- Tsuda M, Ueno S, Inoue K. Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice. Br J Pharmacol. 1999;128:1497-1504. https://doi.org/10.1038/sj.bjp.0702960
- Park MK, Song HC, Yang KY, Ju JS, Ahn DK. Participation of peripheral P2X receptors in orofacial inflammatory nociception in rats. Int J Oral Biol. 2011;36:143-148.
- Han SR, Yeo SP, Lee MK, Bae YC, Ahn DK. Early dexamethasone relieves trigeminal neuropathic pain. J Dent Res. 2010;89:915-920. https://doi.org/10.1177/0022034510374056
- Ahn DK, Choi HS, Yeo SP, Woo YW, Lee MK, Yang GY, Jeon HJ, Park JS, Mokha SS. Blockade of central cyclooxygenase (COX) pathways enhances the cannabinoid-induced antinociceptive effects of inflammatory temporomandibular joint (TMJ) nociception. Pain 2007;132:23-32. https://doi.org/10.1016/j.pain.2007.01.015
- Won KA, Park SH, Kim BK, Baek KS, Yoon DH, Ahn DK. Intracisternal administration of voltage dependent calcium channel blockers attenuates orofacial inflammatory nociceptive behavior in rats. Int J Oral Biol. 2011;36:43-50.
- Yaksh TL, Rudy TA. Chronic catheterization of spinal subarachnoid space. Physiol Behav. 1976;17:1031-1036. https://doi.org/10.1016/0031-9384(76)90029-9
- Yang KY, Kim HK, Jin MY, Ju JS, Ahn DK. Glia dose not participate in antinociceptive effects of gabapentin in rats with trigeminal neuropathic pain. Int J Oral Biol. 2012;37:121-129.
- Surprenant A, Rassendren F, Kawashima E, North RA, Buell G. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 1996; 272:735-738. https://doi.org/10.1126/science.272.5262.735
- Collo G, Neidhart S, Kawashima E, Kosco-Vilbois M, North RA, Buell G. Tissue distribution of the P2X receptor. Neuropharmacology 1997;36:1277-1283. https://doi.org/10.1016/S0028-3908(97)00140-8
- Yu Y, Ugawa S, Ueda T, Ishida Y, Inoue K, Kyaw Nyunt A, Umemura A, Mase M, Yamada K, Shimada S. Cellular localization of P2X7 receptor mRNA in the rat brain. Brain Res. 2008;1194:45-55. https://doi.org/10.1016/j.brainres.2007.11.064
- Franke H, Grosche J, Schadlich H, Krugel U, Allgaier C, Illes P. P2X receptor expression on astrocytes in the nucleus accumbens of rats. Neuroscience 2001;108:421-429. https://doi.org/10.1016/S0306-4522(01)00416-X
- Chessell IP, Hatcher JP, Bountra C, Michel AD, Hughes JP, Green P, Egerton J, Murfin M, Richardson J, Peck WL, Grahames CB, Casula MA, Yiangou Y, Birch R, Anand P, Buell GN. Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain. Pain 2005;114:386-396. https://doi.org/10.1016/j.pain.2005.01.002
- Zhou ZH, Wang JX, Liu BJ, Li M, Lu Y, Chen HS. Contribution of the spinal P2X7 receptors to bee venom-induced nociception and inflammation in conscious rats. Neurosci Lett. 2012;531:145-148. https://doi.org/10.1016/j.neulet.2012.10.040
- Murasaki K, Watanabe M, Takahashi K, Ito G, Suekawa Y, Inubushi T, Hirose N, Uchida T, Tanne K. P2X7 receptor and cytokines contribute to extra-territorial facial pain. J Dent Res. 2013;92:260-265. https://doi.org/10.1177/0022034512474668
- Itoh K, Chiang CY, Li Z, Lee JC, Dostrovsky JO, Sessle BJ. Central sensitization of nociceptive neurons in rat medullary dorsal horn involves purinergic P2X7 receptors. Neuroscience 2011;192:721-731. https://doi.org/10.1016/j.neuroscience.2011.06.083
- McGaraughty S, Wismer CT, Zhu CZ, Mikusa J, Honore P,Chu KL, Lee CH, Faltynek CR, Jarvis MF. Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration. Br J Pharmacol. 2003;140:1381-1388. https://doi.org/10.1038/sj.bjp.0705574
- Guo LH, Trautmann K, Schluesener HJ. Expression of P2X4 receptor by lesional activated microglia during formalin-induced inflammatory pain. J Neuroimmunol. 2005;163:120-127. https://doi.org/10.1016/j.jneuroim.2005.03.007
- Tsuda M, Shigemoto-Mogami Y, Koizumi S, Mizokoshi A, Kohsaka S, Salter MW, Inoue K. P2X4 receptor induced in spinal microglia gate tactile allodynia after nerve injury. Nature 2003;424:778-783. https://doi.org/10.1038/nature01786
- Tsuda M, Kuboyama K, Inoue T, Nagata K, Tozaki-Saitoh H, Inoue K. Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays. Mol Pain 2009;5:28. https://doi.org/10.1186/1744-8069-5-28
- Hu B, Chiang CY, Hu JW, Dostrovsky JO, Sessle BJ. P2X receptors in trigeminal subnucleus caudalis modulate central sensitization in trigeminal subnucleus oralis. J Neurophysiol. 2002;88:1614-1624. https://doi.org/10.1152/jn.2002.88.4.1614
- Hui J, Zhang ZJ, Zhang X, Shen Y, Gao YJ. Repetitive hyperbaric oxygen treatment attenuates complete Freund's adjuvant-induced pain and reduces glia-mediated neuroinflammation in the spinal cord. J Pain 2013;14:747-758. https://doi.org/10.1016/j.jpain.2013.02.003
- Raghavendra V, Tanga FY, DeLeo JA. Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS. Eur J Neurosci. 2004;20:467-473. https://doi.org/10.1111/j.1460-9568.2004.03514.x
- Cao H, Zhang YQ. Spinal glial activation contributes to pathological pain states. Neurosci Biobehav Rev. 2008;32:972-983. https://doi.org/10.1016/j.neubiorev.2008.03.009
- Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996;19:312-318. https://doi.org/10.1016/0166-2236(96)10049-7
- Dong Y, Benveniste EN. Immune function of astrocytes. Glia 2001;36:180-190. https://doi.org/10.1002/glia.1107
- Milligan ED, Watkins LR. Pathological and protective roles of glia in chronic pain. Nat Rev Neurosci. 2009;10:23-36. https://doi.org/10.1038/nrn2533
- Watkins LR, Maier SF. Glia: a novel drug discovery target for clinical pain. Nat Rev Drug Discov. 2003;2:973-985. https://doi.org/10.1038/nrd1251
- Miller RJ, Jung H, Bhangoo SK, White FA. Handb Exp Pharmacol. 2009;194:417-449. https://doi.org/10.1007/978-3-540-79090-7_12
- Saab CY, Waxman SG, Hains BC. Alarm curse? The pain of neuroinflammation. Brain Res Rev. 2008;58:226-235. https://doi.org/10.1016/j.brainresrev.2008.04.002
- Surprenant A, North RA. Singaling at purinergic P2X receptors. Annu Rev Physiol. 2009;71:333-359. https://doi.org/10.1146/annurev.physiol.70.113006.100630