Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
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Usefulness of the Doppler Flow of the Ophthalmic Artery in the Evaluation of Carotid and Coronary Atherosclerosis

  • Hong, Seung Pyo (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Park, Yon Woong (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Lee, Chan Wook (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Park, Joung Won (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Bae, Kyung Ryun (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Jun, Seung Woon (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Lee, Young Soo (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Lee, Jin Bae (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Ryu, Jae Kean (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Choi, Ji Yong (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Chang, Sung Guk (Department of Cardiology, Daegu Catholic University Medical Center) ;
  • Kim, Kee Sik (Department of Cardiology, Daegu Catholic University Medical Center)
  • Received : 2013.09.13
  • Accepted : 2014.09.22
  • Published : 2014.11.30
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Abstract

Background and Objectives: There is little information about the relationship between the Doppler flow of the ophthalmic artery (OA) and carotid and coronary atherosclerosis. The aim of the investigation was to assess the clinical usefulness of the Doppler flow of the OA to estimate the severity of carotid and coronary atherosclerosis. Subjects and Methods: The study was a retrospective analysis of the findings in 140 patients (mean age: 60 years, male: 64%) who underwent coronary angiography (CA) for the evaluation of typical angina between July 2010 and October 2011 in our single center. The severity of coronary artery stenosis was based on the Gensini score (GS). Significant coronary artery disease (CAD) was defined as the obstruction of over 75% of the major coronary arteries confirmed with CA. The pulsed Doppler flow of the OA and carotid ultrasound were performed before CA. Results: The mean systolic velocity/mean diastolic velocity (MSV/MDV), pulsatile index and resistance index in the Doppler flow of the OA were identified as significant and independent correlations with carotid intima-media thickness, and MSV/MDV was identified to have a significant and independent correlation with the GS. MSV/MDV >2.1 was the independent predictor for significant CAD {odds ratio (OR) 3.8, 95% confidence interval (CI) 1.5-9.7, p=0.005} and carotid plaque (OR 2.8, 95% CI 1.1-7.0, p=0.028), after adjustment for CAD-associated factors. Conclusion: The Doppler flow of the OA might be a useful predictor of the severity of carotid and coronary atherosclerosis.

Keywords

References

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