Korean Journal of Medicinal Crop Science (한국약용작물학회지)

The Korean Society of Medicinal Crop Science (한국약용작물학회)
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Triterpenoid Saponin Contents of the Leaf, Stem and Root of Codonopsis lanceolata

더덕 잎, 줄기, 뿌리 부위의 Triterpenoid 사포닌 함량

  • Kim, Ji Ah (Division of Forest Biotechnology, Korea Forest Research Institute) ;
  • Moon, Heung Kyu (Division of Forest Biotechnology, Korea Forest Research Institute) ;
  • Choi, Yong Eui (Department of Forest Resources, Kangwon National University)
  • 김지아 (국립산림과학원 산림생명공학과) ;
  • 문흥규 (국립산림과학원 산림생명공학과) ;
  • 최용의 (강원대학교 산림자원학과)
  • Received : 2013.09.04
  • Accepted : 2014.01.02
  • Published : 2014.02.28
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Abstract

Codonopsis lanceolata (Campanulaceae) has been used in traditional medicines, as its roots contain several kinds of 3,28-bidesmosidic triterpenoid saponin with high medicinal values. In this study, we induced hairy root-derived transgenic plants of C. lanceolata and analyzed triterpenoid saponins from the leaf, stem and root. Transgenic plants were regenerated from the hairy roots via somatic embryogenesis. The saponins are lancemaside A, B and E, foetidissimoside A, and aster saponin Hb. Transgenic plants contained richer triterpenoids saponin than wild-type plants. Major saponin lancemaside A was the most abundant saponin in the stem from transgenic-plant, $4.76mg{\cdot}1^{-1}dry$ stem. These results suggest that transgenic plants of C. lanceolata could be used as medicinal materials for the production of triterpene saponins.

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References

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