Applied Science and Convergence Technology

The Korean Vacuum Society (한국진공학회)
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Facile Preparation of Pyrene-templated Hexagonal-shaped Gold Nanoplates

  • Lim, Eun-Kyung (Department of Radiology, Yonsei University) ;
  • Jang, Eunji (Department of Chemical and Biomolecular Engineering, Yonsei University) ;
  • Haam, Seungjoo (YUHS-KRIBB Medical Convergence Research Institute) ;
  • Huh, Yong-Min (Department of Radiology, Yonsei University)
  • Received : 2014.01.07
  • Accepted : 2014.01.21
  • Published : 2014.01.30
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Abstract

We have formulated hexagonal-shaped gold nanoplates in a single-step for photothermal therapy that gold ions to gold particles using pyrenyl dextran as reducible stabilizer and template. They exhibit anisotropic structure with broad surface plasmon resonance (SPR) band into near-infrared (NIR) spectrum enabling photothermal therapy. These gold nanoplates are also confirmed biocompatibility and high uptake efficiency due to binding with dextran molecules on the surface of gold nanoplates and cells. From in vitro phtothermal ablation study under NIR laser, gold nanoplates have the potential to use as photothermal agents.

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