대한임상독성학회지 (Journal of The Korean Society of Clinical Toxicology)
- 제12권2호
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- Pages.46-53
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- 2014
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- 1738-1320(pISSN)
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- 2508-6332(eISSN)
복어 섭취 후 발생한 급성 테트로도톡신 중독 환자의 임상적 특징과 예후 인자 분석
The Clinical Features and Prognostic Factors in Adults with Acute Etrodotoxin Poisoning Caused by Ingesting Puffer Fish
- 조용수 (전남대학교 의과대학 응급의학교실) ;
- 전병조 (전남대학교 의과대학 응급의학교실) ;
- 문정미 (전남대학교 의과대학 응급의학교실) ;
- 류현호 (전남대학교 의과대학 응급의학교실) ;
- 정용훈 (전남대학교 의과대학 응급의학교실) ;
- 이성민 (전남대학교 의과대학 응급의학교실) ;
- 송경환 (전남대학교 의과대학 응급의학교실) ;
- 류진호 (목포중앙병원 응급의학과)
- Jo, Yong Soo (Department of Emergency Medicine, Medical School, Chonnam National University) ;
- Chun, Byeong Jo (Department of Emergency Medicine, Medical School, Chonnam National University) ;
- Moon, Jeong Mi (Department of Emergency Medicine, Medical School, Chonnam National University) ;
- Ryu, Hyun Ho (Department of Emergency Medicine, Medical School, Chonnam National University) ;
- Jung, Yong Hun (Department of Emergency Medicine, Medical School, Chonnam National University) ;
- Lee, Sung Min (Department of Emergency Medicine, Medical School, Chonnam National University) ;
- Song, Kyung Hwan (Department of Emergency Medicine, Medical School, Chonnam National University) ;
- Ryu, Jin Ho (Department of Emergency Medicine, Mokpo Jung-ang Hospital)
- 투고 : 2014.10.17
- 심사 : 2014.11.02
- 발행 : 2014.12.31
초록
Purpose: We conducted this study in order to determine clinical features and prognostic factors in adults with acute tetrodotoxin (TTX) poisoning caused by ingestion of puffer fish. Methods: In this retrospective study, 107 patients were diagnosed with TTX poisoning. The subjects were divided into two groups according to duration of treatment; Group I, patients were discharged within 48 hours (n=76, 71.0%), Group II patients were discharged after more than 48 hours (n=31, 29.0%). Group II was subsequently divided into two subgroups [IIa (n=12, 11.2%), IIb (n=19, 17.8%)] according to the need for mechanical ventilation support. Results: In multivariable logistic regression analysis, the predictors of the need for treatment over 48 hours were dizziness (odds ratio [OR], 4.72; 95% confidence intervals [CI], 1.59-12.83), time interval between onset of symptom and ingestion (OR, 0.56; 95% CI, 0.16-0.97),