Journal of The Korean Dental Society of Anesthesiology (대한치과마취과학회지)

The Korean Dental Society of Anesthsiology (대한치과마취과학회)
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Anaphylactic Shock after Intravenous Injection of Penicillin in a Patient with Maxillary Osteonecrosis: Report of a Case

상악골괴사 환자에서 페니실린 정주 후 아나필락틱 쇼크: 증례보고

  • Oh, Ji-Hyeon (Department of Dentistry, Wonju Severance Christian Hospital, Yonsei University) ;
  • Son, Jeong-Seog (Department of Dentistry, Wonju Severance Christian Hospital, Yonsei University) ;
  • Choi, Byung-Ho (Department of Dentistry, Wonju Severance Christian Hospital, Yonsei University) ;
  • Lee, Jeong-Sub (Department of Dentistry, Wonju Severance Christian Hospital, Yonsei University) ;
  • Kim, Ji-Hun (Department of Dentistry, Wonju Severance Christian Hospital, Yonsei University) ;
  • Yoo, Jae-Ha (Department of Dentistry, Wonju Severance Christian Hospital, Yonsei University)
  • 오지현 (연세대학교 원주의과대학 원주세브란스기독병원 치과학교실) ;
  • 손정석 (연세대학교 원주의과대학 원주세브란스기독병원 치과학교실) ;
  • 최병호 (연세대학교 원주의과대학 원주세브란스기독병원 치과학교실) ;
  • 이정섭 (연세대학교 원주의과대학 원주세브란스기독병원 치과학교실) ;
  • 김지훈 (연세대학교 원주의과대학 원주세브란스기독병원 치과학교실) ;
  • 유재하 (연세대학교 원주의과대학 원주세브란스기독병원 치과학교실)
  • Received : 2014.11.24
  • Accepted : 2015.01.07
  • Published : 2014.12.31
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Abstract

Generalized anaphylaxis is a most dramatic and acutely life-threatening allergic reaction and may cause death within a few minutes. Differential diagnosis of anaphylaxis is made by clinical signs, such as, mental change, respiratory distress, hypotension, hypoglycemia, urticaria and angioedema. Especially, insulin reaction, myocardial infarction and vasovagal syncope are considered as differential diagnosis. In cases of fatal anaphylaxis, respiratory and cardiovascular disturbances predominate and are evident early in the reaction. This is a case report of the intensive care of anaphylactic shock after intravenous injection of the penicillin in a old medically compromised patient with the maxillary osteonecrosis. The anaphylactic shock symptoms, such as, unconsciousness, respiratory disorder, no pulsation on carotid artery and cardiopulmonary arrest are occurred in intravenous injection of augmentin 1.2 g after the skin test. In spite of immediate emergency cares, such as intravenous injection of epinephrine, endotracheal intubation, cardiopulmonary resuscitation, and continuous intensive care, the patient is expired in 58 hours after anaphylactic shock attack.

Keywords

References

  1. Institute of Medical Education: Emergency Medical Care, supplementary edition. Seoul, Seoul National University Publishing Co. 1994, pp 92-6.
  2. Korean Society of Family Medicine: Textbook of family medicine, clinical part. Seoul, Kyechook Publishing Co. 2002, pp 234-9.
  3. Korean Society of Internal Medicine: Textbook of Harrison's internal medicine, 16th edition. Seoul, Jung Dam Publishing Co. 1997, pp 1759-66.
  4. Korean Society of Dental Anesthesiologist: Medical emergencies in dental office, sixth ed. Seoul, DaeHan Narae Publishing Co. 2009, pp397-427.
  5. YS Cho: Dental treatment and allergy. Journal of Korean Dental Society of Anesthesiology. 2001; 2: 49-52.
  6. Malamed SF: Medical emergencies in dental office, 4th ed. Saint Louis, Mosby. 1993, pp 347-75.
  7. Spark RP: Fatal anaphylaxis to oral penicillin, Am J Clin Pathol 1971;56:407-11. https://doi.org/10.1093/ajcp/56.3.407
  8. Lieberman P: The use of antihistamines in the prevention and treatment of anaphylaxis and anaphylactoid reactions. J Allergy Clin immunol 1990; 86: 684-797. https://doi.org/10.1016/S0091-6749(05)80241-6
  9. Barach EM, Nowak BM, Lee TG: Epinephrine for treatment of anaphylactic shock. JAMA 1984; 251: 2118-22. https://doi.org/10.1001/jama.1984.03340400046024
  10. Ruggiero SL, Fantasia J, Carlson E: Bisphosphonaterelated osteonecrosis of the jaw: background and guidelines for diagnosis, staging and management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006; 102: 433-41. https://doi.org/10.1016/j.tripleo.2006.06.004
  11. Chaudhry AN, Ruggiero SL: Osteonecrosis and bisphosphonates in oral and maxillofacial surgery. Oral Maxillofac Surg Clin North Am 2007; 19: 199-206. https://doi.org/10.1016/j.coms.2007.01.005
  12. Gutta R, Louis PJ: Bisphosphonates and osteonecrosis of the jaws: science and rationale. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 104: 186-93. https://doi.org/10.1016/j.tripleo.2006.12.004
  13. Koulocheris P, Weyer N, Liebehenschel N: Suppurative maxillary sinusitis in patients with bisphosphonateassociated osteonecrosis of the maxilla: report of 2 cases. J Oral Maxillofac Surg 2008; 66: 539-42. https://doi.org/10.1016/j.joms.2007.05.014
  14. The Korean Endocrine Society, the Korean Society of Bone Metabolism, the Korean Society of Osteoporosis, the Korean Association of Oral and Maxillofacial Surgeons: Bisphosphonate related osteonecrosis of the jaw (BRONJ)-position statement of Korea. J Korean Endocr Soc 2009; 24: 227-30. https://doi.org/10.3803/jkes.2009.24.4.227
  15. Korean Association of Oral and Maxillofacial Surgeons: Textbook of oral and maxillofacial surgery, 3rd edition. Seoul, Medical and Dental Publishing Co. 2010, pp 129-84.
  16. Topazian RG and Goldberg MH: Management of infections of the oral and maxillofacial regions, 1st ed. Philadelphia, WB Saunders Co. 1981, pp 173-266.
  17. KW Kim, MJ Kim, YG Kim, JR Kim, YW Park, HS Park et al: Contemporary oral and maxillofacial surgery. Seoul, Narae Publishing, Co. 1999, pp 392-417.
  18. KW Kim, GW Kim, SK Kim, YG Kim, JY Kim, HG Kim et al: Oral and maxillofacial infection. Seoul, Jee Sung Publishing Co. 2007, pp 49-163.
  19. Waldbott GL: Anaphylactic death from penicillin, JAMA 1949; 139: 526-27. https://doi.org/10.1001/jama.1949.72900250002008