DOI QR코드

DOI QR Code

발효 유무에 따른 콜롬비아 커피와 루왁커피의 항산화 활성 비교연구

A Comparison of Antioxidant Effects among Non-fermented and Fermented Columbian Coffee, and Luwak Coffee Beans

  • 김송숙 (구미대학교 식품영양전공)
  • Kim, Song-Suk (Major in Food & Nutritional Sciences, Gumi University)
  • 투고 : 2014.11.09
  • 심사 : 2014.12.08
  • 발행 : 2014.12.31

초록

The purpose of this study was to investigate the antioxidant effects of non-fermented (CAC) and Monascus pilosus-fermented Columbia arabica coffee (FCAC), as well as Luwak coffee (LC) beans. The results indicated that total polyphenols content (mg/g of dry basis) was highest in CAC (70.69), followed by LC (62.07), and FCAC (41.38). However, the ratio of total flavonoids/polyphenols in FCAC was the highest. In terms of electron donating ability (%, coffee mg/mL), CAC was significantly higher than LC and FCAC. Regardless of fermentation, ferric reducing antioxidant powers were similar in CAC and FCAC and lowest in LC. LC also had the highest inhibitory activity against xanthine oxidase (XO). However FAAC had the highest inhibitory activity against aldehyde oxidase (AO), with nearly three times the levels found in CAC and LC. According to the above results, FCAC had a higher ratio of flavonoids/polyphenols and iron chelating activity than CAC. FCAC also had the highest AO inhibitory activity among the three experimental coffee beans. The results suggest that further studies are required to evaluate the bioactive components of various coffee beans so as to determine the potential benefits that coffee may have on preventing oxidative stress-related conditions.

키워드

참고문헌

  1. Atoui AK, Mansouri A, Boskou G, Kefalas P. 2005. Tea and herbal infusions: their antioxidant activity and phenolic profile. Food Chem 89(1):27-36 https://doi.org/10.1016/j.foodchem.2004.01.075
  2. Avallone S, Brillouet JM, Guyot G, Olguin E, Guiraud JP. 2002. Involvement of pectolytic micro-organisms in coffee fermentation. Inter J Food Sci Technol 37(2):191-198 https://doi.org/10.1046/j.1365-2621.2002.00556.x
  3. Belitz HD, Grosch W. 1986. Food Chemistry. pp 688-696. Springer-Verlag Berlin. Heiderberg
  4. Bekedam EK, Schols HA, Cammerer B, Kroh LW, van Boekel MA, Smit G. 2008. Electron spin resonance (ESR) studies on the formation of roasting-induced antioxidative structures in coffee brews at different degree of roast. J Agric Food Chem 56(12):4597-4604 https://doi.org/10.1021/jf8004004
  5. Benzie IF, Strain JJ. 1996. The ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: the FRAP assay. Anal Biochem 239(1):70-76 https://doi.org/10.1006/abio.1996.0292
  6. Blois MS. 1958. Antioxidant determination by the use of a stable free radical. Nature 181:1199-1200 https://doi.org/10.1038/1811199a0
  7. Bravo J, Arbillaga L, de Pena MP, Cid C. 2013. Antioxidant and genoprotective effects of spent coffee extracts in human cells. Food Chem Toxicol 60:397-403 https://doi.org/10.1016/j.fct.2013.08.002
  8. Brown JP. 1988. Role of the gut flora intoxicity and cancer. ed. Rowland IR. Academic Press. San Diego, CA. USA pp 109-144
  9. Choi CH, Song ES, Kim SJ, Kang MH. 2003. Antioxidative activities of Castanea crenata Flos. methanol extracts. Korean J Food Sci Technol 35(6):1216-1220
  10. Choi MJ, Yu T. 2004. Effects of red-yeast-rice supplementation on bone mineral density and bone mineral content in overiectomized rats. J Nutr Health 37(6):2288-3886
  11. Chu YF, Brown PH, Lyle BJ, Chen Y, Black RM, Williams CE, Lin YC, Hsu CW, Cheng IH. 2009. Roasted coffees high in lipophilc antioxidants and chlorogenic acid lactones are more neuroprotective than green coffees. J Agric Food Chem 57(20):9801-9808 https://doi.org/10.1021/jf902095z
  12. Croft KD. 1998. The chemistry and biological effects of flavonoids and phenolic acids. Ann NY Acad Sci 854(1):435-442 https://doi.org/10.1111/j.1749-6632.1998.tb09922.x
  13. Devasagayam TP, Kamat JP, Mohan H, Kesavan PC. 1996. Caffein as an antioxidant: inhibition of lipid peroxidation induced by reactive oxygen species. Biochim Biophys Acta 1282(1):63-70 https://doi.org/10.1016/0005-2736(96)00040-5
  14. Dinis TCP, Madeira VMC, Almeida LM. 1994. Action of phenolic derivatives (acetaminophen, salicylate, and 5-amino salicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Arch Biochem Biophys 315(1): 161-169 https://doi.org/10.1006/abbi.1994.1485
  15. Dixon RA, Dey PM, Lamb CJ. 1983. Phytoalexins: enzymology and molecular biology. Advances in enzymology and related areas of molecular biology. John Wiley & Sons, Inc.. USA pp 1-20
  16. Dorea J, Costa T. 2005. Is coffee a functional food? British J Nutr 93(6):773-782 https://doi.org/10.1079/BJN20051370
  17. Elekofehinti OO, Kamdem JP, Bolingon AA, Athayde ML, Lopes SR, Wazuk EP, Kade IJ, Adanlawo IG, Rocha JBT. 2013. African eggplant (Solanum anguivi Lam.) fruit with bioactive polyphenolic compunds exert in vitro antioxidant properties and inhibits $Ca^{2+}$-induced mitochondrial swelling. Asian Pac J Trop Biomed 3(10):757-766 https://doi.org/10.1016/S2221-1691(13)60152-5
  18. Fukuzawa K, Seko T, Minami K, Terao J. 1993. Dynamics of iron-ascorbate-induced lipid peroxidation in charged and uncharged phospholipid vesicles. Lipids 28(6):497-503 https://doi.org/10.1007/BF02536080
  19. Germano MP, D'Angelo V, Biasini T, Sanogo R, De Pasquale R, Catania S. 2006. Evaluation of the antioxidant properties and bioavalilability of free and bound phenoilc acids from Trichilia emetica Vahl.. J Ethnophamacol 105(3):368-373 https://doi.org/10.1016/j.jep.2005.11.029
  20. Halliwell B. 2006. Reactive oxygen species and the central nervous system. J Neurochem 59:1609-1623
  21. Hamzeh-Mivehroud M, Rahmani S, Feizi MA, Dastmalchi S, Rashidi MR. 2014. In vitro and in silico studies to explore structural features of flavonoids for aldehyde oxidase inhibition. Arch Pharm 347(10):738-747 https://doi.org/10.1002/ardp.201400076
  22. Huynh NT, Van Camp J, Smagghe G, Raes K. 2014. Improved release and metabolism of flavonoids by steered fermentation processes: A review. Int J Mol Sci 15(11):19369-19388 https://doi.org/10.3390/ijms151119369
  23. Ikeda H, Kimura Y, Masaki M, Iwahashi H. 2011. Caffeic acid inhibits the formation of 1-hydroxyethyl radical in the reaction mixture of rat liver microsomes with ethanol partly through ots metal chelating activity. J Clin Biochem Nutr 48(3):187-193 https://doi.org/10.3164/jcbn.10-45
  24. Jeon SM, Bok SH, Jang MK, Lee MK, Nam KT, Park YB, Rhee SJ, Choi MS. 2001. Antioxidative activity of naringin and lovastatin in high cholesterol-fed rabbits. Life Sci 69(24): 855-2866 https://doi.org/10.1016/S0024-3205(01)01179-1
  25. Jeong SJ, Lee JH, Song HN. 2004. Screening for antioxidant activity of plant medicinal extracts. J Korean Soc Appl Biol Chem 47(1):135-140
  26. Jumhawan U, Putri SP, Marwani E, Bamba T, Fukusaki E. 2013. Selection of discriminant markers for authentication of Asian palm civet coffee(Kopi Luwak): a metabolomics approach. J Agric Food Chem 61(33):7994-8001 https://doi.org/10.1021/jf401819s
  27. Kell DB. 2009. Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascualr and other progressive inflammatory and degenerative diseases. Med Genomic 2(2):1755-8794
  28. Kelly EH, Anthony RT, Dennis JB. 2002. Flavonoid antioxidants: chemistry, metabolism and sructure-activity relationship. J Nutr Biochem 13(10):572-584 https://doi.org/10.1016/S0955-2863(02)00208-5
  29. Kim MH, Kim JG, Choi JH. 2014. Antioxidant activity and changes in major functional components of fermented Gastrodia elata Blume. Korean J Food Nutr 27(4):684-691 https://doi.org/10.9799/ksfan.2014.27.4.684
  30. Kim MJ, Kim SS, Lee SI. 2012. Quality characteristics and content of ploysaccharides in green green tea fermented by Monascus pilosus. Prev Nutr Food Sci 17(4):293-298 https://doi.org/10.3746/pnf.2012.17.4.293
  31. Korea Customs Service(KCS). 2012. The recent coffee market trend. Available from: http://www.customs.go.kr. Accessed from: July 20, 2012
  32. Kwon HN, Park JR, Jeon JR. 2008. Antioxidative and hepatoprotective effects of Acer tegmentosum M. extracts. J Korean Soc Food Sci Nutr 37(11):1389-1394 https://doi.org/10.3746/jkfn.2008.37.11.1389
  33. Kuo CF, Chyau CC, Wang TS, Li CR, Hu TJ. 2009. Enhanced antioxidant anf anti-inflammatory activities of monascus pilosus fermented products by addition of turmeric to the medium. Food Chem 116(4):915-922 https://doi.org/10.1016/j.foodchem.2009.03.047
  34. Labat-Robert J, Robert L. 2014. Longevity and aging. Role of free radicals and Xanthine oxidase. Pathol Biol 62(2):61-66 https://doi.org/10.1016/j.patbio.2014.02.009
  35. Lee KJ, Jeong HG. 2007. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicol Lett 173(2):80-87 https://doi.org/10.1016/j.toxlet.2007.06.008
  36. Lee SI, Kim SD, Lee YK, Kim MJ, Lee IA, Choi JK, Suh JW. 2013. Dietary effects of black bean fermented by Monascus pilosus on body weight, serum lipid profiles and activities of hepatic antioxidative enzymes in mice fed high fat diets. J Nutr Health 46(1):5-14
  37. Lee SI, Lee YK, Kimm SD, Kang YH, Suh JW. 2012. Antioxidative activity of Smilax china L. leaf teas fermented by different strains. Korean J Food Nutr 25(4):807-819 https://doi.org/10.9799/ksfan.2012.25.4.807
  38. Lee SS, Lee JH, Lee IH. 2013. Strain improvement by overexpression of the laeA gene in Monasus pilosus for the production of Monascus-fermented rice. J Microbiol Biotechnol 23(7):959-965 https://doi.org/10.4014/jmb.1303.03026
  39. Lee YK, Lee SI, Kim JS, Yang SH, Lee IA, Kim SD, Suh JW. 2012. Antioxidant activity of green tea fermented with Monascus pilosus. J Appl Biol Chem 55(1):19-25 https://doi.org/10.3839/jabc.2011.054
  40. Lin YL, Wang TH, Lee MH, Su NW. 2008. Biologically active components and nutraceuticals in the Monascus-fermented rice: a riview, Appl Microbiol Bioltechnol 77(5):965-973 https://doi.org/10.1007/s00253-007-1256-6
  41. Ludwig IA, Bravo J, De Pena MP, Cid C. 2013. Effect of sugar addition (torrefacto) during roasting process on antioxidant capacity and phenolics of coffee. Food Sci Technol 51(2): 553-559
  42. Maia L, Mira L. 2002. Xanthine oxidase and aldehyde oxidase: A simple procedure for the simultaneous purification from rat liver. Arch Biochem Biophys 400(1):48-53 https://doi.org/10.1006/abbi.2002.2781
  43. Marcone MF. 2004. Composition and properties of Indonesian palm civet coffee. (Kopi Luwak) and Ethiopian civet coffee. Food Res Int 37(9):901-912 https://doi.org/10.1016/j.foodres.2004.05.008
  44. Marklund S, Marklund G. 1974. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47(3):468-474
  45. Meda A, Lamien CE, Romito M, Millogo J, Nacoulma OG. 2005. Determination of the total phenolic, flavonoid and proline contents in burkina fasan honey, as well as their radical scavenging activity. Food Chem 91(3):571-577 https://doi.org/10.1016/j.foodchem.2004.10.006
  46. Minamisawa M, Yoshida S, Takai N. 2004. Determination of biologically active substances in roasted coffees using diode-array HPLC system. Jpn Soc Anal Chem 20:325-328
  47. Minussi RC, Rossi M, Bologna L, Cordi L, Rotilio D, Pastore GM, Duran N. 2003. Phenolic compounds and total antioxidant potential of commercial wines. Food Chem 82(3): 409-416 https://doi.org/10.1016/S0308-8146(02)00590-3
  48. Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo IC. 2005. Contribution of chlorogenic acids to the iron-reducing ativity of coffee beverages. J Agri Food Chem 53(5):1399-1402 https://doi.org/10.1021/jf0485436
  49. Nabavi SM, Daglia M, Sureda A. 2014. Editorial: Dietary polyphenols: We beyond the antioxidant capacity. Curr Pham Biotechol 15:297 https://doi.org/10.2174/138920101504140825112518
  50. Oka K. 2007. Pharmacological bases of coffee nutrients for dibates prevention. Yakugaku Zasshi 127(11):1825-1836 https://doi.org/10.1248/yakushi.127.1825
  51. Osawa T. 1994. Novel natural antioxidant for utilization in food and biological system. pp 241-251. In: Postharvest Biochemistry of Plant Food Material in the Tropics. Uritani I, Garcia VV, Mendoza EM (eds). Japan Scientific Societies Press. Tokyo, Japan
  52. Ozyurek M, Bektasoglu B, Guclu K, Apak R. 2009. Measurement of xanthine oxidase inhibition activity of phenolics and flavonoids with a modified cupric reducing antioxidant capacity method. Anal Chim Acta 636(1):42-50 https://doi.org/10.1016/j.aca.2009.01.037
  53. Parr AJ, Bolwell IP. 2002. Phenols in the plant and in man. The potential for possible nutritional enhancement of the diet by modifying the phenols contents or profile. J Sci Food Agric 80(7):985-1012
  54. Patakova P. 2013. Monascus secondary metabolites: production and biological activity. J Ind Microbiol Bitechnol 40(2): 169-181 https://doi.org/10.1007/s10295-012-1216-8
  55. Pellegrini N, Serafini M, Colombi B, Del Rio D, Salvatore S, Bianchi M, Brighenti F. 2003. Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays. J Nutr 133(9):2812-2819
  56. Rajagopalan KV, Fridovich I, Handler P. 1962. Hepatic aldehyde oxidase. I. Purification and properties. J Biol Chem 237: 922-928
  57. Rashidi MR, Nazemiyeh H. 2010. Inhibitory effects of flavonoids on molybdenum hydroxylases activity. Expert Opin Drug Metab Toxicol 6(2):133-152 https://doi.org/10.1517/17425250903426164
  58. Sato Y, Itagaki S, Kurokawa T, Ogura J, Kobayashi M, Hirano T, Sugawara M, Iseki K. 2011. In vitro and in vivo antioxidant properties of chlorogenic acid and caffeic acid. Int J Pharm 403(1-2):136-138 https://doi.org/10.1016/j.ijpharm.2010.09.035
  59. Shi M, Yang Y, Wang Q, Zhang Y, Wang Y, Zhang Z. 2012. Production of total polyphenol from fermented soybean curd residue by Lentinus edodes. Int J Food Sci Technol 47(6):1215-1221 https://doi.org/10.1111/j.1365-2621.2012.02961.x
  60. Stirpe F, Della Corte E. 1972. The regulation of rat liver xanthine oxidase. Conversion in vitro of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purification of the enzyme. Biochem J 126(3):739-745
  61. Torel J, Gillard J, Gillard P. 1986. Antioxidant activity of flavonoids and reactivity with peroxy radical. Phytochem 25(2):383-385 https://doi.org/10.1016/S0031-9422(00)85485-0
  62. Woelore WM. 1993. Optimum fermentation protocols for Arabica coffee under Ethiopian conditions. In: Association Scientifique Internationale Du Cafe. The 15th International Scientific Colloquium on Coffee, Montpellier, Paris Association Scientifique Internationale. pp 727-733
  63. Yanagimoto K, Ochi H, Lee KG, Shibamoto T. 2004. Antioxidative activities of fractions obtained from brewed coffee. J Agric Food Chem 52(3):592-596 https://doi.org/10.1021/jf030317t
  64. Yang CW, Mousa SA. 2012. The effect of red yeast rice (Monascus purpureus) in dyslipidemia and other disorders. Complement Ther Med 20(6):466-474 https://doi.org/10.1016/j.ctim.2012.07.004
  65. Yesbergenova Z, Yang G, Oron E, Soffer D, Fluhr R, Sagi M. 2005. The plant Mo-hydroxylases aldehyde oxidase and xanthine dehydrogenase have distinct reactive oxigen species signatures asnd are indiced by drought abd abscisic acid. Plant J 42(6):862-876 https://doi.org/10.1111/j.1365-313X.2005.02422.x
  66. Yoshida Y, Hayakawa M, Niki E. 2008. Evaluation of the antioxidant effects of coffee and its components using the biomarkers hydroxyoctadecadienoic acid and isoprostane. J Oleo Sci 57(12):691-697 https://doi.org/10.5650/jos.57.691
  67. Zheng Y, Xin Y, Shi X, Guo Y. 2010. Anti-cancer effect of rubropunctatin against human gastric carcinoma cells BGC-823. Appl Microbiol Biotechnol 88(5):1169-1177 https://doi.org/10.1007/s00253-010-2834-6

피인용 문헌

  1. 커피음용행동의 의미와 목적에 대한 개념도 분석 vol.19, pp.4, 2014, https://doi.org/10.14695/kjsos.2016.19.4.55