The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
권호 표지
DOI QR코드

DOI QR Code

A Case Report of Precocious Puberty in a Female Patient : Significant Improvement in Controlling the Sex Hormone Levels

성조숙증으로 진단된 여자 환아에서 호르몬 수치가 개선된 치험 1례

  • 임영권 (아이조아한의원 수원점) ;
  • 허광욱 (아이조아한의원 수원점) ;
  • 박송이 (아이조아한의원 수원점) ;
  • 서경석 (아이조아한의원 평택점) ;
  • 천상렬 (아이조아한의원 부산점) ;
  • 이석진 (아이조아한의원 성북점) ;
  • 이훈 (경희맑은사람한의원) ;
  • 김호철 (경희대학교 한의과대학 본초학교실)
  • Received : 2014.10.31
  • Accepted : 2014.11.17
  • Published : 2014.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives The purpose of this study is to find out how taking oriental herbal medicine may affect the sex hormone levels in a patient who was diagnosed with prematurity. Methods We prescribed 120 cc of oriental herbal medicine twice daily for a month to a patient suspected of the precocious puberty due to 11 pg/ml of the estradiol level. Upon finishing the course of oriental herbal medicine, the patient was retested for the follicular stimulating hormone, luteinizng hormone and estradiol levels. Results After administration, all levels of luteininzing hormone, follicular stimulating hormone and estradiol were decreased. There was no diagnosable evidence for the idiopathic central precocious puberty in the gonadotropin releasing hormone stimulation. Conclusions Oriental herbal medicine is a good alternative treatment of choice for the precocious puberty. However, more in-depth studies are to be followed.

Keywords

References

  1. Rosenfield RL, Cooke DW, Radovick S. Puberty and its Disorders in the Female In: Sperling MA editor Pediatric endocrinology, 3rd ed. Philadelphia: Saunders Co. 2008:530-609.
  2. Hong CH. Textbook of Pediatrics, 8th ed. Seoul: Korea Testbook Publishing Co. 2012:959-62.
  3. Shim KS, Bae CW, Yang YJ. A comparative study of the puberty suppression effect of geonadotropin releasing hormone agonist in precocious or early puberty girls. Korean J Pediatr. 2008;51(6):634-5. https://doi.org/10.3345/kjp.2008.51.6.634
  4. Seoul:Health Insurance Review & Assessment Service; 2014 Oct, Available from: http://www.hira.or.kr/rd/dissdic/infoSickList.do?pgmid=HIRAA020044020200
  5. Seoul:Health Insurance Review & Assessment Service;cited 2011 May 16, Available from: http://www.hira.or.kr/dummy.do?pgmid=HIRAA020041000000&cmsurl=/cms/notice/02/1205871_24959.html
  6. Kim KB. Textbook of pediatrics of oriental medicine. Seoul: Uisungdang. 2010:852-3.
  7. Hong CH. Textbook of Pediatrics, 8th ed. Seoul: Korea Testbook Publishing Co. 2012:959-62
  8. Shim KS, Kim JT. Therapy for idiopathic precocious puberty in children. J Korean Med Assoc. 2011;54(9):953-6 https://doi.org/10.5124/jkma.2011.54.9.953
  9. Hong EJ, Han HS. Growth promoting effect of combined gonadotropin releasing hormone analogue and growth hormone therapy in early pubertal girls with predicted low adult heights. Korean J Pediatrics. 2007;50(7):678-85. https://doi.org/10.3345/kjp.2007.50.7.678
  10. Yim YG, Min SR, Hur KW, Kim HM. Relationship between bone age, chronological age, anthropometric parameters, and diagnosed pulse rate on secondary sexual character development of child-adolescence. J Korean Med. 2014;35(1):88-98. https://doi.org/10.13048/jkm.14009
  11. Seo JY, Yoon IS. The comparison of predicted adult height change and height gain after gonadotropin releasing hormone agonist and combined growth hormone treatment in girls with idiopathic central precocious puberty. Korean J Pediatr. 2006;49(3):305-11. https://doi.org/10.3345/kjp.2006.49.3.305
  12. Kim KH, Shin DG, Kin DH. Estimated factors and clinical characteristics of children diagnosed with idiopathic prcocious puberty. J Pediatr Korean Med. 2011;25(2):111-20.
  13. Kin JE, Yan SJ, Cho SH. A report on the effect of Jowisengchung-tang in 2 cases of precocious puberty. J Korean Obstet Gynecol. 2013;26(2):178-87. https://doi.org/10.15204/jkobgy.2013.26.2.178
  14. Jiang YP, Liu YG, Chen HC. Effect of aqueous extract of Radix Paeoniae Rubra against carbon tetrachloride induced liver fibrosis in rat. Herald Med. 2004;23:527-9.
  15. Kim CM, Shin MK, Ahn DK, Yi KS. The encyclopedia of oriental herbal medicine. Seoul: Jeongdam. 1997:1678-85.
  16. Gao L, Wang J, Li F, Deng Y, Gao SJ. Literature based analysis on relationship of symptoms, drugs, therapies in treatment of intestinal medicine. Tradit Chin Med. 2014;34(1):106-14. https://doi.org/10.1016/S0254-6272(14)60063-7
  17. Kim JS, Na CS. Effect of Rehmanniae Radix and Pear Phenolic compound on the STZ treated mice for induction of diabetes. J Korean Soc Food Sci Nutr. 2004;33(1):66-71. https://doi.org/10.3746/jkfn.2004.33.1.066
  18. Kim CM, Shin MK, Ahn DK, Yi KS. The encyclopedia of oriental herbal medicine. Seoul: Jeongdam. 1997:2472-6.
  19. Chen HY, Huang BS. Identifying Chinese herbal medicine for premenstrual syndrome : implications from a nationwide database. BMC Complement Altern Med. 2014;27(14):206
  20. Chen HY, Lin YH. Investigation on chinese herbal medicine for primary dysmenorrhea : implication from a nationwide prescription database in Taiwan. Complement Ther Med. 2014;22(1):116-25. https://doi.org/10.1016/j.ctim.2013.11.012
  21. Yu CH, Liu PH. Traditional chinese medicine for idiopathic precocious puberty: A hospital-based retrospective observational study. Complement Ther Med. 2014;22(2):258-65. https://doi.org/10.1016/j.ctim.2014.01.002
  22. Jing Li, Yanyan Sun. Effects of nourishing "Yin"- removing "Fire" chinese herb mixture on the differential expression of GABAA receptor ${\alpha}$ subunits in hypotha- lamus of precocious puberty female rat. Chinese medi- cine. 2013;4(3):10.
  23. Lee MJ, Chang GT. The study for precocious puberty in recent journals of traditional chinese medicine. J Pediatr Korean Med. 2008;22(1):163-87.

Cited by

  1. A Case Report of Efficacy of Growth Height and Peak-Luteinizing Hormone Level Suppression on Idiopathic Gonadotropin-Dependent Precocious Puberty Patient Using Herbal Remedy, Aesopjiyoun-tang vol.36, pp.4, 2015, https://doi.org/10.13048/jkm.15042
  2. 성조숙 증상을 보이는 여아들의 HRV의 특성 연구 vol.29, pp.3, 2014, https://doi.org/10.15204/jkobgy.2016.29.3.010
  3. 성조숙증 치료에 대한 임상 연구 동향 -최근 중의학 저널을 중심으로- vol.31, pp.1, 2017, https://doi.org/10.7778/jpkm.2017.31.1.063
  4. 특발성 성조숙증으로 진단받은 환아 2례에 대한 증례보고 vol.31, pp.1, 2014, https://doi.org/10.7778/jpkm.2017.31.1.074
  5. 한약 치료를 이용한 여성 특발성 성조숙증의 임상연구에 대한 문헌고찰 vol.30, pp.3, 2014, https://doi.org/10.15204/jkobgy.2017.30.3.020
  6. 한약 치료를 이용한 여성 특발성 성조숙증의 임상연구에 대한 문헌고찰 vol.30, pp.3, 2014, https://doi.org/10.15204/jkobgy.2017.30.3.020