KSBB Journal

  • 제28권4호
  • /
  • Pages.244-248
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  • 2013
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  • 1225-7117(pISSN)
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  • 2288-8268(eISSN)
한국생물공학회 (The Korean Society for Biotechnology and Bioengineering)
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사과 '히로사키' 캘러스 추출물의 기능성 화장품 소재로서의 특성

Functional Characterization of Callus Extracts of Apple 'Hirosaki' for Cosmetic Materials

  • 고승희 (바이오스펙트럼(주) 생명과학연구소) ;
  • 김영수 (바이오스펙트럼(주) 생명과학연구소) ;
  • 이진혁 (바이오스펙트럼(주) 생명과학연구소) ;
  • 김일현 (바이오스펙트럼(주) 생명과학연구소) ;
  • 김승범 (바이오스펙트럼(주) 생명과학연구소) ;
  • 노경백 (바이오스펙트럼(주) 생명과학연구소) ;
  • 신승우 (바이오스펙트럼(주) 생명과학연구소) ;
  • 정은선 (바이오스펙트럼(주) 생명과학연구소) ;
  • 박덕훈 (바이오스펙트럼(주) 생명과학연구소)
  • 투고 : 2013.07.04
  • 심사 : 2013.08.26
  • 발행 : 2013.08.30
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초록

In order to investigate functional characterization of callus extracts of apple 'Hirosaki' for cosmetic materials, biological activities of its extracts including wrinkle improvement, hair growth, and anti-inflammatory effect were investigated. The callus extract showed similar activity with TGF-${\beta}$ used as positive control at 50 ${\mu}g/mL$ in the test of collagen synthesis, and increased 40% of proliferation of hair follicle dermal papilla cells. Especially, in case of anti-inflammatory effect, callus extract inhibited about 50% of COX-2 expression which was known as response for intermediating inflammation, and about 70% of eotaxin-1 production which was increased by atopy dermatitis.

키워드

참고문헌

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