Polymer(Korea) (폴리머)

The Polymer Society of Korea (한국고분자학회)
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Preparation of Syndiotactic Poly(vinyl alcohol) Microfibrils with Radiopaque Inorganic Particles

방사선불투과성 무기입자를 첨가한 교대배열 폴리비닐알코올 마이크로피브릴의 제조

  • Jo, Hye Won (Department of Nano, Medical and Polymer Materials, Yeungnam University) ;
  • Cha, Jin Wook (Department of Nano, Medical and Polymer Materials, Yeungnam University) ;
  • Han, Sung Soo (Department of Nano, Medical and Polymer Materials, Yeungnam University) ;
  • Lee, Joon Seok (Department of Textile Engineering and Technology, Yeungnam University) ;
  • Oh, Tae Hwan (Department of Nano, Medical and Polymer Materials, Yeungnam University)
  • 조혜원 (영남대학교 나노메디컬유기재료공학과) ;
  • 차진욱 (영남대학교 나노메디컬유기재료공학과) ;
  • 한성수 (영남대학교 나노메디컬유기재료공학과) ;
  • 이준석 (영남대학교 융합섬유공학과) ;
  • 오태환 (영남대학교 나노메디컬유기재료공학과)
  • Received : 2013.02.20
  • Accepted : 2013.05.10
  • Published : 2013.09.25
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Abstract

Poly(vinyl pivalate) (PVPi) was bulk polymerized to make poly(vinyl alcohol) (PVA) microfibrils to apply for polymeric embolization coils replacing metalic coils. Then, syndiotactic PVA (s-PVA) microfibrils having number-average degree of polymerization of 1100 and s-diad content of 60.4% were prepared via saponification of the PVPi with no separate spinning process. To make s-PVA microfibrils with radiopacity, zirconium dioxide ($ZrO_2$) and barium sulfate ($BaSO_4$) were added into s-PVA microfibrils during saponification. The computed tomography (CT) value indicating radiopacity reached up to over 1000 when the amount of $ZrO_2$ and $BaSO_4$ were 12 and 6 wt%, respectively.

폴리비닐알코올(poly(vinyl alcohol), PVA) 마이크로피브릴(microfibrils)을 금속 색전코일을 대체할 수 있는 고분자 색전코일에 적용하기 위해 벌크중합으로 폴리피발산비닐(poly(vinyl pivalate), PVPi)을 제조하고 비누화 공정에서 방사공정 없이 중합도가 1100 교대배열 다이애드(diad)기 함량 60.4%인 교대배열 PVA(syndiotactic PVA, s-PVA) 마이크로피브릴을 제조하였다. 또한 별도의 조영제의 투여가 불필요한 마이크로피브릴 제조를 위해 방사선불투과성 물질인 이산화지르코늄과 황산바륨을 비누화 공정에서 첨가하여 방사성불투과성 교대배열 PVA 마이크로피브릴을 제조하였고, 무기입자 함유 s-PVA 마이크로피브릴의 computed tomography(CT) value 값 측정 결과 이산화지르코늄의 함량이 12 wt% 이상에서, 황산바륨은 6 wt% 이상에서 1000 이상의 우수한 방사선불투과성을 나타내는 것을 확인하였다.

Keywords

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