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전기방사와 가교결합을 통한 알지네이트 나노섬유 제조

Preparation of Alginate Nanofiber via Electrospinning and Crosslinking

  • 구민경 (건국대학교 공과대학 유기나노시스템공학과) ;
  • 양진욱 (건국대학교 공과대학 유기나노시스템공학과) ;
  • 김형섭 (건국대학교 공과대학 유기나노시스템공학과)
  • Ku, Min Kyung (Department of Organic and Nano System Engineering, Konkuk University) ;
  • Yang, Jin Uk (Department of Organic and Nano System Engineering, Konkuk University) ;
  • Kim, Hyungsup (Department of Organic and Nano System Engineering, Konkuk University)
  • 투고 : 2013.08.18
  • 심사 : 2013.10.05
  • 발행 : 2013.10.31

초록

In this study, alginate fiber prepared by electrospinning was crosslinked using CaCl2. In order to improve the spinnability, glycerol was added to the aqueous solution of sodium alginate. The solution containing glycerol exhibited the crossover point of G' and G" at low frequencies and decreased the solution viscosity. A solution containing 4 wt% alginate was suitable for electrospinning and maintained the fiber shape. At higher alginate concentrations, the electrospun fiber transformed into a membrane-like structure. The crosslinked web exhibited improved thermal stability and reduced crystallinity.

키워드

참고문헌

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피인용 문헌

  1. Preparation of Electrospun Alginate Webs for Transdermal Drug Delivery Systems vol.52, pp.1, 2015, https://doi.org/10.12772/TSE.2015.52.014