한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제30권5호
  • /
  • Pages.333-338
  • /
  • 2013
  • /
  • 1598-298X(pISSN)
  • /
  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

한국의 서울에 사는 길 고양이와 집 고양이에서 고양이 범백혈구감소증 바이러스의 유병률

Prevalence of Feline Panleukopenia Virus in Stray and Household Cats in Seoul, Korea

  • 김승곤 (건국대학교 수의과대학 내과학교실) ;
  • 이교임 (건국대학교 수의과대학 내과학교실) ;
  • 김하정 (플로리다 주립대학교 수의과대학 소동물 임상연구) ;
  • 박희명 (건국대학교 수의과대학 내과학교실)
  • Kim, Seung-Gon (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Lee, Kyo-Im (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Kim, Ha-Jung (Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida) ;
  • Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
  • 심사 : 2013.10.23
  • 발행 : 2013.10.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

우리는 한국의 서울에 있는 다른 지역에 사는 길 고양이와 집 고양이의 범백혈구감소증 바이러스의 유병률을 조사하였다. 혈액 샘플은 200마리 고양이 (길 고양이 100마리와 집 고양이)에서 수집하였으며 모든 샘플은 중합효소 반응검사를 실시하였다. 전체적인 고양이 범백혈구감소증 바이러스의 유병률은 2%이다. 검사를 통해 양성 고양이 중 3% (100 분의 3)은 길 고양이이며 1% (100분의 1)은 집 고양이였다. 고양이 백혈구감소증 바이러스의 발생은 성묘 (1살이상, 0.5%) 보다 자묘 (1살이내, 1.5%)에서 더 높았다. 건강한 고양이의 양성률은 1.8% (3/166)이며 아픈 고양이의 양성률은 2.2% (1/44)이다. 예방 접종한 고양이의 양성률은 1.3% (1/77)이었고 예방 접종하지 않은 고양이의 양성률은 2.3% (3/133)이다. 항체검사와 비교시 고양이 범백혈구 바이러스 항원의 검출은 길 고양이와 집 고양이의 현재 질병 감염 상태를 암시할 수 있다. 따라서 항원검사는 질병의 진단과 치료에 도움을 줄 수 있다. 결론적으로 우리의 연구는 현재까지 서울에서 고양이 범백혈구감소증 바이러스의 유병률을 평가한 적이 없었기 때문에 비교적 중요하다. 고양이 범백혈구감소증 바이러스의 유병률은 길 고양이와 어린 고양이에서 높았다. 따라서 고양이 범백혈구감소증 바이러스 발생을 예방하기 위해서는 적절한 예방접종과 감시가 중요하다.

We investigated the prevalence of feline panleukopenia virus (FPV) in stray and household cats in different regions of Seoul, Republic of Korea. Blood samples were collected from a total of 200 cats (100 stray cats and 100 household cats) and examined by polymerase chain reaction (PCR). The overall prevalence of FPV was 2%. Among test-positive cats, 3% (3/100) were stray cats and 1% (1/100) was a household cat. The incidence of FPV was higher in juvenile cats (< 1 year, 1.5%) than in adult cats (> 1-year-old, 0.5%). The FPV-positive rates of healthy infected cats and sick cats were 1.9% (3/156) and 2.2% (1/44), respectively. We found the positive rate of vaccinated and unvaccinated cats to be 1.3% (1/77) and 2.4% (3/123), respectively. Unlike antibody tests, FPV antigen tests detected current infections in stray and household cats. Therefore, these tests can help in disease diagnosis and treatment. To our knowledge, our study is the first to survey the prevalence of FPV in different cat populations across Seoul. We found a high prevalence of FPV infection in stray and juvenile cats. Therefore, proper vaccination and surveillance are important to prevent FPV outbreaks.

키워드

참고문헌

  1. Addie DD, Toth S, Thompson H, Greenwood N, Jarrett JO. Detection of feline parvovirus in dying pedigree kitten. Vet Rec 1998; 142: 353-356. https://doi.org/10.1136/vr.142.14.353
  2. An DJ, Jeong W, Jeoung HY, Yoon SH, Kim HJ, Park JY, Park BK. Phylogenetic analysis of feline panleukopenia virus (FPLV) strains in Korean cats. Res Vet Sci 2011; 90: 163-167. https://doi.org/10.1016/j.rvsc.2010.05.010
  3. Barker IK, Povey RC, Voigt DR. Response of mink, skunk, red fox and raccoon to inoculation with mink virus enteritis, feline panleukopenia and canine parvovirus and prevalence of antibody to parvovirus in wild carnivores in Ontario. Can J Comp Med 1983; 47: 188-197.
  4. Blanco K, Prendas J, Cortes R, Jimenez C, Dolz G. Seroprevalence of viral infections in domestic cats in Costa Rica. J Vet Medi Sci 2009; 71: 661-663. https://doi.org/10.1292/jvms.71.661
  5. Cave TA, Thompson H, Reid SWJ, Hodgson DR, Addie DD. Kitten mortality in the United Kingdom: a retrospective analysis of 274 histopathological examinations (1986 to 2000). Vet Rec 2002; 151: 497-501. https://doi.org/10.1136/vr.151.17.497
  6. Greene CE, Scott FW. Feline panleukopenia. In: Infectious Diseases of the Dog and Cat. 2nd ed. Philadelphia: WB Saunders. 1998; 52.
  7. Hofmann-Lehmann R, Fehr D, Grob M, Elgizoli M, Packer C, Martenson JS, O'Brien SJ, Lutz H. Prevalence of Antibodies to Feline Parvovirus, Calicivirus, Herpesvirus, Coronavirus, and Immunodeficiency Virus and of Feline Leukemia Virus Antigen and the Interrelationship of These Viral Infections in Free-Ranging Lions in East Africa. Clin Vaccine Immunol 1996; 3: 554-562.
  8. Horiuchi M, Ishiguro N, Sinagawa M, Mochizuki M. Production of monoclonal antibodies specific to both feline panleukopenia virus (FPLV) and mink enteritis virus, and characterization of escape mutants from FPLV strains, abstr. 5067, p. 302. In Program and abstracts of the 43rd Annual Meeting of the Society of Japanese Virologists, 31 October to 2 November, 1995, Okayama, Japan.
  9. Horzinek MC. Vaccine use and disease prevalence in dogs and cats. Vet Microbiol 2006; 117: 2-8. https://doi.org/10.1016/j.vetmic.2006.04.002
  10. Kariatsumari T, Horiuchi M, Hama E, Yaguchi K, Ishiguro N, Goto H, Shinagawa M. Construction and nucleotide sequence analysis of an infectious DNA clone of the autonomous parvovirus, mink enteritis virus. J Gen Virol 1991; 72: 867-875 https://doi.org/10.1099/0022-1317-72-4-867
  11. Kruse BD, Unterer S, Horlacher K, Sauter-Louis K, and Hartmann K. Prognostic Factors in cats with Feline panleukopenia. J Vet Intern Med 2010; 24: 1271-1276. https://doi.org/10.1111/j.1939-1676.2010.0604.x
  12. Lee H, Lee M, Lee J, Kim H, Yoon J, Choi J. Ultrasonographic diagnosis of a fibrinonecrotic colonic cast in a kitten with feline panleukopenia virus. J Small Anim Pract 2012; 53: 416-418. https://doi.org/10.1111/j.1748-5827.2012.01223.x
  13. Lee SM, Yoon IJ, Lee KJ, Lee KY, Kim MK, Choi HW. Effect of a trivalent (FPV, FHV, FCV) inactivated vaccine in kittens. Kor J Vet Res 2005; 45: 311-323.
  14. Levy JK, Crawford PC, Lappin MR, Dubovi EJ, Levy MG, Alleman R, Tucker SJ, Clifford EL. Infectious Diseases of Dogs and Cats on Isabela Island, Galapagos. J Vet Intern Med 2008; 22: 60-65. https://doi.org/10.1111/j.1939-1676.2007.0034.x
  15. Macieira DB, Menezes RCA, Damico CB, Almosny NR, McLane HL, Daggy JK, Messick JB. Prevalence and risk factors for hemoplasmas in domestic cats naturally infected with feline immunodeficiency virus and/or feline leukemia virus in Rio de Janeiro - Brazil. J Feline Med Surg 2008; 10: 120-129. https://doi.org/10.1016/j.jfms.2007.08.002
  16. Millán J, Rodríguez A. A serological survey of common feline pathogens in free-living European wildcats (Felis silvestris) in central Spain. Eur J Wildl Res 2009; 55: 285-291. https://doi.org/10.1007/s10344-008-0246-z
  17. Mochizuki M, Horiuchi M, Hiragi H, San Gabiel MC, Yasuda N, Uno T. Isolation of Canine Parvovirus from a Cat Manifesting Clinical Signs of Feline Panleukopenia. J Clin Microbiol 1996; 34: 2101-2105.
  18. Mosallanejad B, Avizeh R, Ghorbanpoor NM. Antigenic detection of Feline Panleukopenia virus (FPV) in diarrhoeic companion cats in Ahvaz area. Iranian J Vet Res 2009; 10: 289-293.
  19. Nakamura K, Ikeda Y, Miyazawa T, Nguyen NT, Duong DD, Le KH, Vo SD, Phan LV, Mikami T, Takahashi E. Comparison of prevalence of feline herpesvirus type 1, calicivirus and parvovirus infections in domestic and leopard cats in Vietnam. J Vet Med Sci 1999; 61: 1313-1315. https://doi.org/10.1292/jvms.61.1313
  20. Ohtaishi N, Hachiya N. Aging Techniques from Annual Layers in Teeth and Bone. Contemporary Mammalogy in China and Japan. Mammalogical Society of Japan 1985; 180-190.
  21. Ostrowski S, Van Vuuren M, Lenain DM, Durand A. A serologic survey of wild felids from central west Saudi Arabia. J Wildlife Dis 2003; 39: 696-701. https://doi.org/10.7589/0090-3558-39.3.696
  22. Sykes J. Vaccination regimes for dogs and cats. Vet Focus 2012; 22: 29-35. https://doi.org/10.1055/s-0034-1381874
  23. Truyen U, Addie D, Belák S, Boucraut-Baralon C, Egberink H, Frymus T, Gruffydd-Jones T, Hartmann K, Hosie MJ, Lloret A, Lutz H, Marsilio F, Pennisi MG, Radford AD, Thiry E, Horzinek MC. Feline panleukopenia. ABCD guidelines on prevention and management. J Feline Med Surg 2009; 11: 538-546. https://doi.org/10.1016/j.jfms.2009.05.002