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건강검진자료에 의한 일반 성인들의 혈압과 혈청지질 및 비만지표와의 관련성

Relationships Between Blood Pressure and Serum Lipids, Obesity Indices in Adults using Health Examination Data

  • 윤석한 (충남대학교 대학원 보건학과)
  • Yoon, Seok-Han (Department of Public Health, Graduate School of Chungnam National University)
  • 투고 : 2013.08.08
  • 심사 : 2013.09.06
  • 발행 : 2013.09.30

초록

본 연구의 목적은 건강검진을 받은 일반 성인들의 혈압과 혈청지질치 및 비만지표와의 관련성을 검토하고자 하였다. 조사대상은 2012년 한 대학교병원에서 건강검진을 받았던 20세 이상 일반 성인 2,734명(남자 1,344명, 여자 1,390명)을 대상으로 하였다. 조사는 해당 대학병원 연구윤리위원회(IRB)의 승인을 받은 후 대상자들의 종합건강검진 결과표와 문진표로부터 자료를 수집하였으며, 조사항목으로는 피조사자들의 성별, 연령, 안정 시 혈압(SBP, DBP), 혈청지질치(TC, HDL-C, LDL-C, TG, AI) 및 비만관련지표(BMI, 체지방률, 허리둘레) 등이었다. 연구결과, TC, TG, AI는 남녀 모두 고혈압군이 비고혈압군보다 유의하게 높았으며, HDL-C는 여자에서 비고혈압군이 고혈압군보다 유의하게 높은 반면, LDL-C는 고혈압군이 비고혈압군보다 유의하게 높았다. BMI, 체지방률, 허리둘레는 남녀 모두 고혈압군이 비고혈압군보다 유의하게 높았다. SBP와 DBP는 남녀 모두 연령, TC, TG, AI, BMI, 체지방률 및 허리둘레와 유의한 양의 상관관계를 보였다. 그러나 HDL-C와 LDL-C는 여자에서만 각각 음의 상관관계와 양의 상관관계를 보였다. 연령을 조정한 고혈압발생위험비는 남녀 모두에서 TC, TG, BMI, 허리둘레가 정상인 군보다 비정상인 군에서 유의하게 증가하였으며, HDL-C는 여자에서만, 체지방률은 남자에서만 유의하게 증가하였다. 이상과 같은 결과는 혈압이 여러 혈청지질치 및 비만지표들과 유의한 관련성을 갖고 있음을 시사한다.

The purpose of this study was to investigate the association of blood pressures and serum lipids, obesity indices in adults who examined health checkup. Study subjects were 2,734 adults of 20 years and over (1,344 males, 1,390 females), who underwent health package check-up at an university hospital during one year of 2012. We observed the age, sex, SBP, DBP, TC, TG, HDL-C, LDL-C, AI, BMI, body fat rate and waist circumference of study subjects after confirmed IRB of the hospital. As a results, TC, TG, AI was significantly higher in the group of hypertension than that of normotensive in both sex, but in only female, HDL-C and LDL-C was higher in the each group of normotensive and hypertension. BMI, body fat rate and waist circumference was significantly higher in the group of hypertension than that of normotensive in both sex. SBP and DBP was positive correlated with TC, TG, AI, BMI, body fat rate and waist circumference, but HDL-C and LDL-C was each correlated with positive and negative in female only. Age-adjusted odds ratio for hypertension by blood serum lipids and obesity indices was significantly increased in the group of abnormal than normal of TC, TG, BMI, but HDL-C and waist circumference was each increased in the abnormal group of female, and in the abnormal group of male. Above results suggested that the blood pressure related with serum lipid levels and obesity indices.

키워드

참고문헌

  1. http://kosis.kr
  2. Ministry for Health Welfare and Family Affairs. Korea National Health and Nutrition Examination Survey p54, 2011.
  3. Hubert HB, Feinleib M, Mcnamara PM, Castelli WP. Obesity as an independent risk factor for cardiovascular disease: A 26-year follow up of participants in the Framingham Heart study. Circulation, 67:968-977, 1983. DOI: http://dx.doi.org/10.1161/01.CIR.67.5.968
  4. Hauner H, Stangl D, Schmatz C et al. Body fat distribution in men with angiographically confirmed coronary artery disease. Athrosclerosis, 85:203-210, 1990. DOI: http://dx.doi.org/10.1016/0021-9150(90)90112-V
  5. Hsieh SD, Yoshinaga H. Abdominal fat distribution and coronary heart disease risk factors in men-wasit/height ratio as a simple and useful predictor. Int J Obes Relat Metab Disord 19:585-589, 1995.
  6. Ko GTC, Chan JCN, Woo J, Lau E et al. Simple anthropometric indexes and cardiovascular risk factors in Chinese. Int J Obes Relat Metab Disord 21:995-1001, 1997. DOI: http://dx.doi.org/10.1038/sj.ijo.0800508
  7. Wang J, Thornton JC, Russell M, Burastero S, Heymsfield S Jr, Pierson RN. Asians have lower body mass index(BMI) but higher percent body fat than do whites: comparisons of anthropometric measurements. Am J Clin Nutr, 60:23-28, 1994. https://doi.org/10.1093/ajcn/60.1.23
  8. Cho YC, Song IS. Charastics of BMI, blood pressure and serum lipid levels according to age and health behavior in industrial workers. J Korean Public Health Assoc, 26(2):143-151, 2000.
  9. Park KR, Cho YC. The abnormal rates of blood pressures and blood biochemical properties with BMI in health checkup examinees. Journal of the Korea Academia-Industrial Cooperation Society, 11(12):4843-4853, 2010. DOI: http://dx.doi.org/10.5762/KAIS.2010.11.12.4843
  10. Tilvis RS, Erkinjintti T, Sulkava R, et al. serum lipids and fatty acids in ischemic strikes. Am Heart J, 113:615-619, 1987. DOI: http://dx.doi.org/10.1016/0002-8703(87)90642-9
  11. Feldman RG, Albrink MJ. Serum lipids and cerebrovascular disease. Arch Neurol, 10:91-100, 1964. DOI: http://dx.doi.org/10.1001/archneur.1964.00460130095013
  12. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 18:499, 1972.
  13. NECP. Expert panel on defection, evaluation and treatment of high blood cholesterol in adults. JAMA, 269(23):3015-302, 1993. DOI: http://dx.doi.org/10.1001/jama.269.23.3015
  14. WHO. The Asia-Pacific Perspective: Redefining obesity and its treatment. Sydney, Australia, Health Communications Australia Pty Ltd, 2000.
  15. Park YH, Rhee CS, Lee YC. Distribution Patterns of Serum Lipids by Degree of Obesity and Blood Pressure in Korean Adults. Korean J perinatology, 3(2):165-180, 1993.
  16. Cho YC, Song IS. Charastics of BMI, blood pressure and serum lipid levels according to age and health behavior in industrial workers. J Korean Public Health Assoc, 26(2):143-151, 2000.
  17. Kim ES, Kim KH, Cho YC. Prevalence of clustering of coronary risk factors in health checkup examinees. Journal of The Korea Academia-Industrial Cooperation Society 10(3):625-633, 2009. DOI: http://dx.doi.org/10.5762/KAIS.2009.10.3.625
  18. Park KR, Cho YC. The association of blood pressures and blood biochemical properties with BMI in health checkup examinees. Journal of the Korea Academia- Industrial Cooperation Society, 12(7):3072-3081, 2011. DOI: http://dx.doi.org/10.5762/KAIS.2011.12.7.3072
  19. Wang SB, Cho YC. Body mass index and subsequent risk of hypertension, hyperglycemia and hypercholesterolemia in health checkup examinees. Journal of the Korea Academia-Industrial Cooperation Society, 12(6):2677-2684, 2011. DOI: http://dx.doi.org/10.5762/KAIS.2011.12.6.2677
  20. Nakura I. Relationship between change in body mass index and blood pressure in urban residents. Japan J Publ Health, 52(7):607-617, 2005.
  21. Sasaki M, Inagaki S, Fujii T, Toshinai K, Nakao C, Ueya E, Koseki S, Sato Y, Haga S. Blood biological properties in male workers analysed according to body type. Japan Society for Occupational Health 39:178-183, 1997.
  22. Fukui A. Relationship between obesity, total plasma cholesterol and blood pressure in male adults. Japan Soc Occup Health, 119-124, 2000.
  23. Ishikawa-Takata K, Ohta T, Moritaki K. Obesity, weight change, and risk for hypertension, diabetes, and hypercholesterolemia in Japanese men. Eur J Clin Nutr, 56:601-607, 2002. DOI: http://dx.doi.org/10.1038/sj.ejcn.1601364
  24. Yamagishi K, Hosoda T, Sairenchi T, Mori K, Tomita H, Nishimura A, Tanigawa T, Iso H. Body mass index and subsequent risk of hypertension, diabetes and hypercholesterolemia in population-based sample of Japanese. Japan J Publ Health, 50(11):1050-1057, 2003.
  25. Beaglehole R, magnus P. the search for new factors for coronary heart disease: occupational therapy for epidemiologists? Int J Epidemiol, 31:1117-1122, 2002. DOI: http://dx.doi.org/10.1093/ije/31.6.1117
  26. Vos LE, Oren A, Uiterwaal C, Gorrssen WHM, Grobbee DE, Bots ML. Adolescent blood pressure and blood pressure tracking into young adulthood are related to subclinical atherosclerosis; The atherosclerosis risk in young adults(ARYA) study. Am J Hypretens, 16:549-555, 2003. DOI: http://dx.doi.org/10.1016/S0895-7061(03)00857-4