대한수의학회지 (Korean Journal of Veterinary Research)

  • 제53권3호
  • /
  • Pages.181-184
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  • 2013
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  • 2466-1384(pISSN)
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  • 2466-1392(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
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개의 이영양성 피부 석회증에 대한 diltiazem의 적용 1례

Clinical trial of diltiazem on dystrophic calcinosis cutis in a dog

  • 조나영 (충남대학교 수의과대학 동물의과학연구소) ;
  • 조대희 (충남대학교 수의과대학 동물의과학연구소) ;
  • 최호정 (충남대학교 수의과대학 동물의과학연구소) ;
  • 정성목 (충남대학교 수의과대학 동물의과학연구소) ;
  • 이영원 (충남대학교 수의과대학 동물의과학연구소) ;
  • 박성준 (충남대학교 수의과대학 동물의과학연구소)
  • Cho, Na-Young (College of Veterinary Medicine Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Cho, Dae-Hee (College of Veterinary Medicine Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Choi, Ho-Jung (College of Veterinary Medicine Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Jeong, Seong-Mok (College of Veterinary Medicine Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Lee, Young-Won (College of Veterinary Medicine Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Park, Seong-Jun (College of Veterinary Medicine Research Institute of Veterinary Medicine, Chungnam National University)
  • 투고 : 2012.11.08
  • 심사 : 2013.07.23
  • 발행 : 2013.09.30
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초록

Dystrophic calcinosis cutis associated with spontaneous hyperadrenocorticism was diagnosed in a 8-year-old female Chihuahua dog with erythematous, erosive, numerous papules, plaques, and crusts on the bilateral trunk, and inguinal region. Serum biochemical abnormalities included increases in alkaline phosphatase (ALP), alanine aminotransferase (ALT), gamma-glutamyl transpeptidase (GGT), and cholesterol. Radiographs showed mild hepatomegaly and subcutaneous lobulated calcific deposits. Histopathologic examination demonstrated diffuse deposition of basophilic calcified material in the dermis. Von Kossa's stain confirmed calcium deposition. Therapy with diltiazem was useful in resolving calcinosis.

키워드

참고문헌

  1. Braddock JA , Church DB, Robertson ID, Watson AD. Trilostane treatment in dogs with pituitary-dependent hyperadrenocorticism. Aust Vet J 2003, 81, 600-607. https://doi.org/10.1111/j.1751-0813.2003.tb12498.x
  2. Gross TL, Ihrke PJ, Walder EJ, Affolter VK. Degenerative, dysplastic and depositional diseases of dermal connective tissue. In: Skin diseases of the dog and cat. 2nd ed. pp. 373- 377, Blackwell science, Iowa, 2005.
  3. Hnilica KA. Canine hyperadrenocorticism. In: Small animal dermatology. 3rd ed. pp. 292-298, Saunders, St. Louis, 2011.
  4. Melian C, Perez-Alenza D, Peterson ME. Hyperadrenocorticism in dogs. In: Ettinger SJ, Feldman EC (eds). Textbook of veterinary internal medicine expert consult. 7th ed. pp. 1816-1839, Saunders, St. Louis, 2010.
  5. Munday JS, Bergen DJ, Roe WD. Generalized calcinosis cutis associated with probable leptospirosis in a dog. Vet Dermatol 2005, 16, 401-406. https://doi.org/10.1111/j.1365-3164.2005.00476.x
  6. Neiger R, Ramsey I, O'Connor J, Hurley KJ, Mooney CT. Trilostane treatment of 78 dogs with pituitary-dependent hyperadrenocorticism. Vet Rec 2002, 150, 799-804. https://doi.org/10.1136/vr.150.26.799
  7. Nelson RW. Disorder of the adrenal gland. In: Nelson RW, Couto CG (eds.). Small animal internal medicine. 3rd ed. pp. 779-798, Mosby, Philadelphia, 2003.
  8. Ogretmen Z, Akay A, Bicakci C, Bicakci HC. Calcinosis cutis universalis. J Eur Acad Dermatol Venereol 2002, 16, 621-624. https://doi.org/10.1046/j.1468-3083.2002.00584.x
  9. Palamaras I. Kyriakis K. Calcium antagonists in dermatology: a review of the evidence and research-based studies. Dermatol Online J 2005, 11, 8.
  10. Rijnberk A, Belshaw BE. An alternative protocol for the medical management of canine pituitary-dependent hyperadrenocorticism. Vet Rec 1988, 122, 486-488. https://doi.org/10.1136/vr.122.20.486
  11. Ruckstuhl NS, Nett CS, Reusch CE. Results of clinical examinations, laboratory tests, and ultrasonography in dogs with pituitary-dependent hyperadrenocorticism treated with trilostane. Am J Vet Res 2002, 63, 506-512. https://doi.org/10.2460/ajvr.2002.63.506
  12. Scott DW, Miller WH, Griffin CE. Neoplastic and nonneoplastic tumors. In: Muller and Kirk's Small animal dermatology. 6th ed. pp. 1398-1399, Saunders, Philadelphia, 2001.
  13. Walsh JS, Fairley JA. Calcifying disorders of the skin. J Am Acad Dermatol 1995, 33, 693-706. https://doi.org/10.1016/0190-9622(95)91803-5
  14. Weinel S, Callen JP. Calcinosis cutis complicating adultonset dermatomyositis. Arch Dermatol 2004, 140, 365-366.

피인용 문헌

  1. Treatment of Calcinosis Cutis with Minocycline in Five Dogs vol.34, pp.2, 2017, https://doi.org/10.17555/jvc.2017.04.34.2.119