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Functional Mediastinal Pheochromocytoma

  • Lee, Jang Hoon (Department of Thoracic and Cardiovascular Surgery, Yeungnam University College of Medicine) ;
  • Lee, Seok Soo (Department of Thoracic and Cardiovascular Surgery, Yeungnam University College of Medicine) ;
  • Lee, Jung Cheul (Department of Thoracic and Cardiovascular Surgery, Yeungnam University College of Medicine) ;
  • Kim, Myeong Su (Department of Thoracic and Cardiovascular Surgery, Yeungnam University College of Medicine) ;
  • Choi, Joon Hyuk (Department of Pathology, Yeungnam University College of Medicine)
  • Received : 2012.08.31
  • Accepted : 2012.10.08
  • Published : 2013.02.05

Abstract

A 36-year-old man visited Yeungnam University Hospital with a sudden onset of palpitation, headache, and was found to be hypertensive. Chest radiography showed a 6 cm sized mass lesion on the posterior mediastinum. A biochemical study showed elevated levels of catecholamines. An I-123 metaiodobenzylguanidine scan revealed a hot uptake lesion on the posterior mediastinum. The patient was prepared for surgery with ${\alpha}$ and ${\beta}$ blocking agents. Two months later, we removed the tumor successfully. A histological study proved that the resected tumor was mediastinal pheochromocytoma. Functional mediastinal pheochromocytomas are rare. Therefore, we reported the case with a literature review.

Keywords

References

  1. Sakamaki Y, Yasukawa M, Kido T. Pheochromocytoma of the posterior mediastinum undiagnosed until the onset of intraoperative hypertension. Gen Thorac Cardiovasc Surg 2008; 56:509-11. https://doi.org/10.1007/s11748-008-0282-3
  2. Singh J, Rana SS, Sharma R, Ghai B, Puri GD. A rare cause of hypertension in children: intrathoracic pheochromocytoma. Pediatr Surg Int 2008;24:865-7. https://doi.org/10.1007/s00383-008-2165-1
  3. Young WF Jr. Paragangliomas: clinical overview. Ann N Y Acad Sci 2006;1073:21-9. https://doi.org/10.1196/annals.1353.002
  4. Hung LC, Liu YS, Tsai YS, Chuang MT. Familial paraganglioma syndrome. Acta Neurol Belg 2011;111:255-6.
  5. Faria J, Valente V, Lima P, Silva JA, Polonia J. Paraganglioma: a case of secondary hypertension. Rev Port Cardiol 2010;29:1583-9.
  6. Spector JA, Willis DN, Ginsburg HB. Paraganglioma (pheochromocytoma) of the posterior mediastinum: a case report and review of the literature. J Pediatr Surg 2003;38:1114-6. https://doi.org/10.1016/S0022-3468(03)00208-2
  7. Petri BJ, van Eijck CH, de Herder WW, Wagner A, de Krijger RR. Phaeochromocytomas and sympathetic paragangliomas. Br J Surg 2009;96:1381-92. https://doi.org/10.1002/bjs.6821
  8. Chao S, Mullins ME, Slanetz PJ. Posterior mediastinal pheochromocytoma. AJR Am J Roentgenol 2001;176:1408. https://doi.org/10.2214/ajr.176.6.1761408