Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Development of Sugar Sensitive Drosophila Cell based ISFET Sensor for Alzheimer's Disease Diagnosis

알츠하이머 진단을 위한 당성분에 민감한 초파리 세포기반 ISFET센서개발

  • Lim, Jeong-Ok (Biomedical Research Institute, Kyungpook National University) ;
  • Yu, Joon-Boo (Materials Science and Metallurgical Engineering, Kyungpook National University) ;
  • Kwon, Jae-Young (Biological Science, Sungkyunkwan University) ;
  • Byun, Hyung-Gi (Department of Information and Communication Engineering, Kangwon Naltional University) ;
  • Huh, Jeung-Soo (Materials Science and Metallurgical Engineering, Kyungpook National University) ;
  • Cho, Won-Ju (Department of Electronic Material Engineering, Kwangwoon Uinversity)
  • Received : 2013.05.23
  • Accepted : 2013.07.18
  • Published : 2013.07.31
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Abstract

In this study a biosensor was developed by using Drosophila cells expressing a gustatory receptor Gr5a and an ion sensitive field effect transistors (ISFETs) sensor device, which demonstrated significant compatibility with the Drosophila cells expressing Gr5a and their response to sugar. These results suggested that the newly developed cell based biosensor has a potential as a simple and easy screening device for Alzheimer's disease in the future.

Keywords

References

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