A Study on Skin Care Effects of Rapeseed Meal Extract

유채박 추출물의 피부미용 효과에 관한 연구

  • Kim, Sun Mi (Department of Beauty and Cosmetology, Graduate School of Industry, Chosun University) ;
  • Na, Myung Soon (Department of Beauty and Cosmetology, Graduate School of Industry, Chosun University)
  • 김선미 (조선대학교 산업대학원 미용향장학과) ;
  • 나명순 (조선대학교 산업대학원 미용향장학과)
  • Received : 2013.06.05
  • Accepted : 2013.06.17
  • Published : 2013.06.27


This research was to investigate the inhibitory effects of tyrosinase, elastase and collagenase using rapeseed meal extract for the functional cosmetics. Gamma-tocopherol and alpha-tocopherol contents were 304.9 and 212.2 mg/kg, respectively. In the case of delta-tocopherol and plastochromanol-8, they were 12.1 and 35.7 mg/kg, respectively. The total phenol content of methanol extract was the highest (49.6 mg/g) which was about 4.96 fold higher than that of water extract. The maximum nitrite scavenging activities of methanol and acetone extract at pH 1.2 were 85.2 and 80.1%, respectively, at 8.0 mg/mL. When the extract concentration of rapeseed meal increased upto 2.0 mg/mL, cell viabilities did not appear to have any significant cytotoxic effect, irrespective of extracts. Tyrosinase and elastase inhibition activities increased from 25.2 to 42.5% and 25.3 to 48.0%, respectively, as methanol extract concentration increased from 0.5 to 1.0 mg/mL. The collagenase inhibition activities of methanol and acetone extracts at 1.0 mg/mL were 67.2 and 68.0%, respectively. These results showed that the methanol and acetone extract of rapeseed meal can be used as a new source of functional cosmetic agent.



  1. Westbrook, C. K ., C. V. Naik, O. Herbinet, W. J. Pitz, M. Mehl, S. M. Sarathy, and H. J. Curran (2002) Detailed chemical kinetic reaction mechanisms for soy and rapesee biodiesel fuels. Comb. Flame. 158: 742-755.
  2. Lee, K. K., J. H. Kim, J. J. Cho, and J. D. Choi (1999) Inhibitory effect of 150 plant extracts on elastase activity and their anti-inflammatory effects. Int. J. Cosmet. Sci. 21: 71-82.
  3. Garrel, C. and M. Fontecave (1995) Nitric Oxide Chemistry and Biology Analysis of Free. Radicals in Biological Systems, pp. 21-35.
  4. Aranjit, C., H., Kaur, and H. C. Kapoor (2002) Antioxidant activity and total phenolic content of some Asian vegetables. Int. J. Food Sci. Tech. 37: 153-161.
  5. Miloslav, sulc, M., J. Lachman, K. Hamouz, and P. Dvorak (2008) Impact of phenolic content on antioxidant activity in yellow and purple-fleshed potatoes grown in the Czech Republic. Biol. Agric. Hortic.: Int. J. Sustain. Prod. Sys. 26: 45-54.
  6. Hwang, E. Y., Y. H. Kong, Y. C. Lee, Y. C. Kim, K. M. Yoo, Y. O. Jo, and S. Y. Choi (2006) Comparison of phenolic compound contents between white and red ginseng and their inhibitory effect on melanin biosynthesis. J. Ginseng Res. 30: 82-87.
  7. Ando, S., O. Ando, Y. Suemoto, and Y. Mishima (1993) Tyrosinase gene transcription and its control by melanogenic inhibitor. J. Invest . Dermatol. 100: 150S-155S.
  8. Kim, J. Y., H. J. Yang, K. H. Lee, S. M. Jeon, Y. J. Ahn, B. R. Won, and S. N. Park (2003) Antioxidative and antiaging effects of Jeju native plant extracts(II). J. Soc. Cosmet. Sci. Korean 33: 165-173.
  9. Jeon, T. W., C. H. Jo, K. H. Kim, and M. W. Byun (2002) Inhibitory effect on tryrosinase and xanthine oxidase and nitrite scavenging activites of Schizandrae Fructus extract gamma irradiation. Korean J. Food Preser. 9: 369-374.
  10. Swann, P. F. (1975) The toxicology of nitrite, nitrate, and N-nitroso compounds. J. Sci. Food Agr. 26: 1761-1764.
  11. Chung, H. J., and K. L. Noh (2000) Screening of electron donating ability, antibacterial activity and nitrite scavenging effect of some herbal extracts. Korean J. Food Sci. 16: 372-377.
  12. Kang, Y. H., Y. K. Park. and G. D. Lee (1996) The nitrite scavenging and electron donating ability of phenolic compounds. Korean Food Sci. Tech. 28: 232-239.
  13. Chung, S. Y., N. K. Kim and S. Yoon (1999) Nitrite scavenging effect of methanol fraction obtained from green yellow vegetable juices. J. Korean Soc. Food Sci. Nut. 28: 342-347.
  14. Yeo, S. G., D. M. Yeum, D. H. Lee, C. W. Ahn, S. B. Kim, and Y. H. Park (1994) The nitrite scavenging effects by component of green tea extracts. J. Korean Soc. Food Sci. Nut. 23: 287-292.
  15. Jin, Q., J. R. Park, J. B. Kim, and M. H. Cha (1999) Physiological activity of Zizyphus jujuba leaf extracts. J. Korean Soc. Food Sci. Nut. 28: 593-598
  16. Bennett, D. C., P. J. Cooper, and I. R. Hart (1987) A line of nontum- origenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growt. Int. J. Cancer 39: 414-418.
  17. Sung, J. H., S. H. Park, D. H. Seo, J. H. Lee, S. W. Hong, and S. S. Hong (2009) Antioxidative and skin-whitening effect of anaqueous extract of Salicornia hebacea. Biosci. Biotech. Biochem. 73: 552-556.
  18. Kazuya, I., K. Noriaki, K. Yukari, M. Kyo, and F. Andtokio (2004) In vitro antioxidative effects and tyrosinase inhibitory activities of seven hydroxycinnamoyl derivatives in green coffee beans. J. Agr. Food Chem. 52: 4893-4898.
  19. Sim, G. S., J. H. Kim, B. C. Lee, D. H. Lee, G. S. Lee, and H. Bae (2008) Inhibitory effects on melanin production in B16 melamona. Yakhak Hoeji. 52: 165-171
  20. Ha, S. E., H. D. Kim,, J. K. Park, Y. O. Chung, H. J. Kim, and N. B. Park (2009) Melanogenesis inhibition effect of Rosa multiflora extracts in B16 melanoma cells. Korean J. Plant Res. 22: 317-322.
  21. Han, Y. S., and E. S. Jung (2003) A study of correlation between antioxidant activity and whitening effect of plant extract. Korean Aesthetic. Soc. 1: 11-22.
  22. Roth, G. J., C. J. Siok, and J. Ozols (1980) Structural characteristics of prostaglandin synthetase from sheep vesicular gland. J. Biol. Chem. 255: 1301-1304.
  23. Grant, N. H., and H. E Alburn (1959) Studies on the collagenases of Clostridium histolyticum. Arch. Biochem. Biophy. 82: 245-255.

Cited by

  1. Protective effect of Korean diet food groups on lymphocyte DNA damage and contribution of each food group to total dietary antioxidant capacity (TDAC) vol.49, pp.5, 2016,