Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Cardiac Lymphoma in a Shih Tzu Dog

씨츄 개에서 발생한 심장 림프종

  • Kim, Tae-Young (Section of Small Animal Internal Medicine, School of Veterinary Medicine and Institute of Veterinary Medicine, Kangwon National University) ;
  • Joo, Jeong-Hoon (OK Animal Hospital) ;
  • Hyun, Changbaig (Section of Small Animal Internal Medicine, School of Veterinary Medicine and Institute of Veterinary Medicine, Kangwon National University)
  • 김태영 (강원대학교 수의학과 소동물 내과교실) ;
  • 주정훈 (진해 오케이 동물병원) ;
  • 현창백 (강원대학교 수의학과 소동물 내과교실)
  • Accepted : 2013.06.11
  • Published : 2013.06.30
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Abstract

A 7 years-old intact female dog (4.8 kg) was referred with primary complaints of enlarged surface lymph nodes, cardiac murmur, coughing and exercise intolerance. Diagnostic imaging studies found cardiomegaly with distended caudal vena cava, marked left ventricular and interventrciular septal thickening and flattening, severe aortic and pulmonic stenosis (~5 m/s), and mitral and tricuspid regurgitation (~4 m/s). Cytology for the samples obtained from submandibular lymph node and left ventricle revealed high grade malignant lymphoma. The case was diagnosed as cardiac lymphoma. The dog was treated with prednisolone (2 mg/kg, PO, q24h), lomustine (80 $mg/m^2$ PO, q3wk), diltiazem (1 mg/kg, PO, q12h) and enalalpril (0.5 mg/kg, PO, q12h). The clinical signs were improved after therapy. The dog is still on the chemotherapy and regularly checked up.

7년령의 암컷 개(4.8 kg)가 표층 림프절 종대, 심잡음, 그리고 운동 불내성을 주증으로 의뢰되었다. 영상진단학상에 후대정맥의 확장, 좌심실벽과 심실 중격의 현저한 비후와 편평화, 심한 대동맥과 폐동맥 협착(~5 m/s), 그리고 이첨판과 삼첨판의 역류(~4 m/s)가 관찰되었다. 하악림프절과 좌심실로부터 취득한 샘플에 대한 세포학적 분석에서 높은 단계의 악성 림프종이 나타났다. 이 증례는 심장 림프종으로 진단되었다. 환자는 prednisolone (2 mg/kg, PO, q24h), lomustine (80 $mg/m^2$ PO, q3wk), diltiazem (1 mg/kg, PO, q12h) 그리고 enalalpril (0.5 mg/kg, PO, q12h)으로 치료되었다. 임상증상은 치료 후에 개선되었다. 현재 환자는 여전히 화학요법을 실시하고 있으며, 주기적으로 상태를 확인중이다.

Keywords

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