Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Epidemiology of Esophageal Cancer in Yanting - Regional Report of a National Screening Programme in China

  • Wang, Xiao (Sichuan Cancer Hospital & Institute) ;
  • Fan, Jin-Chuan (Sichuan Cancer Hospital & Institute) ;
  • Wang, An-Rong (Sichuan Cancer Hospital & Institute) ;
  • Leng, Yue (Department of Public Health and Primary Care, University of Cambridge) ;
  • Li, Jun (Yanting Cancer Institute) ;
  • Bao, Yu (Sichuan Cancer Hospital & Institute) ;
  • Wang, Ying (Sichuan Cancer Hospital & Institute) ;
  • Yang, Qing-Feng (Yanting Cancer Institute) ;
  • Ren, Yu (Yanting Cancer Institute)
  • Published : 2013.04.30
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Abstract

Background and Objectives: Yanting in Sichuan Province is one of the highest risk areas of esophageal cancer (EC) in the world. We here summarize the epidemiology of EC in Yanting using data from the national screening programme during 2006-2011. Methods: Random cluster sampling was used to select a proportion of natural villages from six towns in Yanting, and residents aged 40-69 years old were invited for screening. Participants were screened using endoscopy with iodine staining and then confirmed by histological examinations. Results: The overall detection rates of low-grade hyperplasia (LH), moderate hyperplasia (MH), high-grade hyperplasia (HH), carcinoma in situ (CIS), intramucosal carcinoma (IC) and invasive carcinoma (INC) were 5.33%, 1.28%, 0.68%, 0.15%, 0.06% and 0.29%, respectively. The detection rates of LH, MH, HH and INC increased with age, reaching the peak among those aged 60-65 years, and the prevalences of LH and MH were higher among men than among women. In addition, the detection rates of hyperplasia were much higher in mountainous than in hilly areas. Conclusions: Among the high risk population, there are a great number of people with early-stage EC or precancerous conditions who do not have presenting symptoms. In particular, the elderly, men, or those living in mountainous areas are the most vulnerable population. It is therefore important to reinforce health education and screening services among such high risk populations.

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References

  1. Chen ZF (2008). Analysis of Cohort Endoscopic Screening in High Risk Area of Esophageal Cancer in Taihang Moutain Area. China Cancer, 17, 1001-3 (in Chinese).
  2. Chen JZ, Du HZ, Gu YK, et al (2005). The epidemic tendency analysis of esophageal cancer in Yanting form 1969 to 2003. Sichuan Med J, 26, 3-4 (in Chinese).
  3. Gary D (2001). Stoner and Ashok Gupta Etiology and chemoprevention of esophageal squamous cell carcainoma. Carcinogenesis, 22, 1737-46. https://doi.org/10.1093/carcin/22.11.1737
  4. Hao J, Zhao P, Chen WQ (2012). 2011 Cancer Registration Annual Report. Beijing: Military Med Sci, 1, 206-7 (in Chinese).
  5. Kamangar F, Chow WH, Abnet CC, et al (2009). Environmental causes of esophageal cancer. Gastroenterol Clin North Am, 38, 27-vii. https://doi.org/10.1016/j.gtc.2009.01.004
  6. Li H, Li HQ (2009). Progress in epidemiological studies of esophageal cancer. Chin J Gastrointest Surg, 12, 96-7 (in Chinese).
  7. Li J, Wang D, Jiang CX, et al (2010). The Mortality Trend of Esophageal Cancer from 2004 to 2009 in Yanting, Sichuan Province. China Cancer, 19, 573-6 (in Chinese).
  8. Liu LL, Gao YL, Ji K, et al (2011). Analysis on Deaths Caused by Malignant Tumor in Death Cause Surveillance Areas in Sichuan Province from 2002 to 2007. J Prev Med Inf, 27, 8-10 (in Chinese).
  9. Liu ZC, Lian SY, Wang YX, et al (2010). Prevalence analysis of esophageal carcinoma and precancerous condition in esophageal cancer high risk area. Chin J Clin Oncol, 37, 94-5 (in Chinese).
  10. Ministry of Health Disease Prevention and Control Bureau (2011). Cancer early detection and treatment program. People's Health Publishing House, Beijing1-14 (in Chinese).
  11. National Cancer Center (2012). Cancer Registration Annual Report 2011. Beijing: Military Medical Sciences, 1, 26-8 (in Chinese).
  12. Yamaji T, Inoue M, Sasazuki S, et al (2008). Fruit and vegetable consumption and squamous cell carcinoma of the esophagus in Japan: the JPHC study. Int J Cancer, 123, 1935-1940. https://doi.org/10.1002/ijc.23744
  13. Zhao DL, Yu TT, Wei WQ, et al (2011). An analysis of esophageal cancer esophageal and gastric cardia endoscopic results in Feicheng Shandong. Chin J Prev Med, 45, 662-4 (in Chinese).
  14. Zhong C, Tan JJ, Xu ZX (2011). The etiology of esophageal cancer epidemiology research progress. Henan J Prev Med, 22, 1-10 (in Chinese).
  15. Zou XN, Chen WQ, Zhang SW, et al (2007). Analysis of Esophageal Cancer Incidence and Mortality from 30 Cancer Registries in China from 1998 to 2002. China Cancer, 16 , 142-6 (in Chinese).

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