Asian Pacific Journal of Cancer Prevention

  • 제14권2호
  • /
  • Pages.801-803
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  • 2013
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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Is Sunlight a Predisposing Factor for Triple Negative Breast Cancer in Turkey?

  • Mutlu, Hasan (Department of Medical Oncology, Acibadem Kayseri Hospital) ;
  • Buyukcelik, Abdullah (Department of Internal Medicine, Acibadem University School of Medicine) ;
  • Colak, Taner (Department of General Surgery, Akdeniz University School of Medicine) ;
  • Ozdogan, Mustafa (Department of Medical Oncology, Akdeniz University School of Medicine) ;
  • Erden, Abdulsamet (Department Internal Medicine, Kayseri Training And Research Hospital) ;
  • Aslan, Tuncay (Department Internal Medicine, Kayseri Training And Research Hospital) ;
  • Akca, Zeki (Department of Radiation Oncology, Zeki Akca, Mersin Government Hospital)
  • 발행 : 2013.02.28
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초록

Intraduction: There is known to be a relationship between vitamin D level and more aggresive breast cancer subtypes, especially triple-negative breast cancer (TNBC). It was reported that sunlight exposure has an effect on the prognosis of patients with cancer, possibly related to the conversion of vitamin D to its active form with sunlight. We aimed to evaluate the effect of sunlight exposure on patients with TNBC. Materials-Methods: A total of 1,167 patients with breast cancer from two different regions of Turkey (Antalya and Kayseri, regions having different climate and sunlight exposure intensity over the year) were analysed retrospectively. The ratio of patients with TNBC was identified in those two regions. Results: The ratio of patients with TNBC was 8% and 12% for Kayseri and Antalya regions, respectively, and this difference between the two groups was statistically significant (p=0.021). Discussion: Sunlight exposure may be associated with more prevalent TNBC. This finding should be investigated with a prospective study.

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참고문헌

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