Bulletin of the Korean Chemical Society

  • 제34권6호
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  • Pages.1809-1813
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  • 2013
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  • 0253-2964(pISSN)
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  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Chiral Separation of Basic Compounds on Sulfated β-Cyclodextrin-Coated Zirconia Monolith by Capillary Electrochromatography

  • 투고 : 2013.01.28
  • 심사 : 2013.03.24
  • 발행 : 2013.06.20
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⟨ 이전 논문 다음 논문 ⟩

초록

Sulfated ${\beta}$-cyclodextrin (SCD)-coated zirconia monolith was used as the chiral stationary phase in capillary electrochromatography for enantiomeric separation of basic chiral compounds. SCD adsorbed on the zirconia surface provided a stable chiral stationary phase in reversed-phase eluents. Retention, chiral selectivity and resolution of a set of six basic chiral compounds were measured in eluents of varying pH, composition of methanol and buffer. Optimum mobile phase condition for the separation of the compounds was found to be methanol content of 30%, buffer concentration of 30 mM and pH of 4.0.

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  3. Cyclodextrin-Functionalized Monolithic Capillary Columns: Preparation and Chiral Applications vol.28, pp.2, 2015, https://doi.org/10.1002/chir.22550
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  5. Enantiomeric Recognition and Separation by Chiral Nanoparticles vol.24, pp.6, 2013, https://doi.org/10.3390/molecules24061007
  6. Indirect synchronous fluorescence spectroscopy and direct high‐performance thin‐layer chromatographic methods for enantioseperation of zopiclone and determination of chiral‐switching vol.31, pp.5, 2013, https://doi.org/10.1002/chir.23063