Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Analysis of COPD Patient's Exhaled Breath Using Sensor Array

센서 어레이를 사용한 COPD 환자의 호기분석

  • Yu, Joon-Boo (Bio-Medical Research Institute, Kyungpook National Unversity) ;
  • Lee, Shin-Yup (Department of Internal Medicine, School of Medicine, Kyungpook National University) ;
  • Jeon, Jin-Young (Department of Electronic, Information & Communication Engineering, Kangwon National University) ;
  • Byun, Hyung-Gi (Department of Electronic, Information & Communication Engineering, Kangwon National University) ;
  • Lim, Jeong-Ok (Bio-Medical Research Institute, Kyungpook National Unversity)
  • 유준부 (경북대학교 생명의학연구소) ;
  • 이신엽 (경북대학교 병원) ;
  • 전진영 (강원대학교 전자정보통신공학부) ;
  • 변형기 (강원대학교 전자정보통신공학부) ;
  • 임정옥 (경북대학교 생명의학연구소)
  • Received : 2013.05.06
  • Accepted : 2013.05.20
  • Published : 2013.05.31
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Abstract

The exhaled breath contains gases generated from human body. When disease occurs in the body, exhaled breath may include gas components released from disease metabolism. If we can find specific elements through analysis of the exhaled gases, this approach is an effective way to diagnose the disease. The lung function has a close relationship with exhalation. Exhaled gases from COPD (Chronic Obstructive Pulmonary Disease) patients can be analyzed by gas chromatography-mass spectroscopy (GC-MS) and a gas sensor system. The exhaled breath for healthy person and COPD patients had different components. Significantly more benzendicarboxylic acid was detected from COPD patients than in healthy persons. In addition, patients had a variety of decane. Phosphorous compounds with different isomers were detected from patients. The results obtained by gas sensor system were processed by PCA (Principal Component Analysis). The PCA results revealed distinct difference between the patients and healthy people.

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References

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