Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
권호 표지

Two Cases of Ethylene Glycol Poisoning

에틸렌 글리콜 중독 2례

  • Kim, Jae Jin (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Yun, Sung Hyun (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Jung, Hyun Min (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Kim, Ji Hye (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Han, Seung Baik (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Kim, Jun Sig (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Paik, Jin Hui (Department of Emergency Medicine, College of Medicine, Inha University)
  • 김재진 (인하대학교 의과대학 응급의학교실) ;
  • 윤성현 (인하대학교 의과대학 응급의학교실) ;
  • 정현민 (인하대학교 의과대학 응급의학교실) ;
  • 김지혜 (인하대학교 의과대학 응급의학교실) ;
  • 한승백 (인하대학교 의과대학 응급의학교실) ;
  • 김준식 (인하대학교 의과대학 응급의학교실) ;
  • 백진휘 (인하대학교 의과대학 응급의학교실)
  • Received : 2013.05.23
  • Accepted : 2013.06.07
  • Published : 2013.06.13
Download PDF
⟨ Previous Next ⟩

Abstract

Ethylene glycol poisoning is treated mainly by alcohol dehydrogenase inhibition therapy and hemodialysis. Early recognition and initiation of treatment is important because toxic metabolites increase over time by hepatic metabolism; however, there is no confirmative diagnostic tool in our clinical setting. Therefore, diagnosis is dependent on history, high anion gap acidosis, high osmolal gap, etc.. Diagnosis and treatment are delayed in cases where history taking is not possible, such as a mental changed patient. Authors report on two cases of ethylene glycol poisoning by contrasting clinical outcomes, demonstrating the importance of early diagnosis and treatment for achievement of a good outcome.

Keywords