The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Zolpidem, Is it a Safe Drug for Insomnia Management?

졸피뎀, 과연 안전한 불면증 치료제인가?

  • Park, Kyung Hee (Department of Internal Medicine, Severance Hospital Regional Pharmacovigilance Center, Yonsei University College of Medicine) ;
  • Lee, Jae-Hyun (Department of Internal Medicine, Severance Hospital Regional Pharmacovigilance Center, Yonsei University College of Medicine)
  • 박경희 (연세대학교 의과대학 내과학교실, 세브란스병원 지역의약품안전센터) ;
  • 이재현 (연세대학교 의과대학 내과학교실, 세브란스병원 지역의약품안전센터)
  • Published : 2013.06.01
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Abstract

Zolpidem is one of commonly prescribed hypnotics in worldwide. Zolpidem is more favored than benzodiazepines because of its efficacy and safety profiles. However there were many reports those concerns about adverse drug reactions such as delirium, nightmares and hallucinations. The report of Kim et al. showed that zolpidem induced delirium occurred in 4.0% in inpatients. Moreover, old age and concomitant use of benzodiazepine were risk factors for zolpidem related delirium. Therefore, clinicians carefully consider the risk factors when prescribe zolpidem, and the careful monitoring of patients about various adverse reactions after administration.

Keywords

References

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