DOI QR코드

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Anti-TNF-${\alpha}$ 치료받은 강직성 척추염에서 체중 및 골밀도 변화

Weight Gain and Improvement of Osteoporosis with Anti-TNF Therapy

  • 김태환 (한양대학교 류마티스병원) ;
  • 윤혜진 (한양대학교 류마티스병원)
  • Kim, Tae-Hwan (Hanyang University Hospital for Rheumatic Diseases, Hanyang University College of Medicine) ;
  • Yun, Hyaejin (Hanyang University Hospital for Rheumatic Diseases, Hanyang University College of Medicine)
  • 발행 : 2013.11.01

초록

Ankylosing spondylitis (AS) is a chronic inflammatory disorder primarily involving the sacroiliac joints and spine. It usually affects young people, and bone formation and resorption are implicated in the pathogenesis of AS. Non-steroidal anti-inflammatory drugs (NSAIDs) are the first line therapy and are very effective in most of patients who have inflammatory back pain. If NSAIDs are not effective, anti-TNF-${\alpha}$ agents are strongly recommended in severe inflammatory back pain. Anti-TNF-${\alpha}$ is very effective in most of AS patients. A study by Lee et al. showed that AS patients who were treated with anti-TNF-${\alpha}$ have weight gain and improvement of osteoporosis. In this editorial, studies on the improvement of weight and osteoporosis with anti-TNF-${\alpha}$ agents are reviewed.

키워드

참고문헌

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