Journal of the East Asian Society of Dietary Life (동아시아식생활학회지)

The East Asian Society of Dietary Life (동아시아식생활학회)
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Effects of Alkaline Phosphatase Activity on the Extract of Carthami Semen and Eucommiae Cortex in Human Osteoblast-like MG-63 Cell Line

홍화자와 두충 혼합 추출물이 MG-63 조골세포의 Alkaline Phosphatase 활성에 미치는 영향

  • Received : 2012.11.23
  • Accepted : 2013.02.21
  • Published : 2013.03.07
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Abstract

Carthamus tinctorius L. and Eucommia umoides Oliver are often used in traditional herbal medicines for reducing damage to the liver, kidney, bone and muscle. In the present study, we investigated cell viability and alkaline phosphatase activity in the human osteoblast-like MG-63 cell line with methanol extracts of Carthami Semen (CS) and Eucommiae Cortex (EC) alone or in a mixture (CS+EC). Osteoblast cell viability was evaluated using the MTS assay and alkaline phosphatase activity assays. The cell viability and alkaline phosphatase activity significantly increased in MG-63 osteoblast cells treated with the CS+EC mixture. These findings suggest the CS+EC mixture may have beneficial effects on bone health through the proliferation of osteoblast cells.

Keywords

References

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