한국응용과학기술학회지 (Journal of the Korean Applied Science and Technology)

  • 제30권4호
  • /
  • Pages.622-634
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  • 2013
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  • 1225-9098(pISSN)
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  • 2288-1069(eISSN)
한국응용과학기술학회 (The Korean Society of Applied Science and Technology)
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Obesity, obesity-related diseases and application of animal model in obesity research An overview

  • Park, Byung-Sung (Department of Animal Biotechnology, College of Animal Life Sciences, Kangwon National University) ;
  • Singh, N.K. (Department of Animal Biotechnology, College of Animal Life Sciences, Kangwon National University) ;
  • Reza, A.M.M.T. (Department of Animal Biotechnology, College of Animal Life Sciences, Kangwon National University)
  • 투고 : 2013.12.08
  • 심사 : 2014.01.03
  • 발행 : 2013.12.30
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초록

The multi-origin of obesity and its associated diseases made it's a complex area of biomedical science research and severe health disorder. From the 1970s to onwards this health problem turned to an epidemic without having any report of declining yet and it created a red alert to the health sector. Meanwhile, many animal models have been developed to study the lethal effect of obesity. In consequence, many drugs, therapies and strategies have already been adopted based on the findings of those animal models. However, many complicated things based on molecular and generic mechanism has not been clarified to the date. Thus, it is important to develop a need based animal model for the better understanding and strategic planning to eliminate/avoid the obesity disorder. Therefore, the present review would unveil the pros and cons of presently established animal models for obesity research. In addition, it would indicate the required turning direction for further obesity and obesity based disease research.

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