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과당에서 전환된 5-HMF(5-hydroxymethylfurfural)의 정량적 분석

Quantitative analysis of 5-HMF produced from fructose

  • 심재훈 (충북대학교 농업생명과학대학 목재종이과학과) ;
  • 신수정 (충북대학교 농업생명과학대학 목재종이과학과)
  • Sim, Jaehoon (Department of Wood and Paper Science, College of Agriculture and Life Science, Chungbuk Natl. Univ.) ;
  • Shin, Soo-Jeong (Department of Wood and Paper Science, College of Agriculture and Life Science, Chungbuk Natl. Univ.)
  • 투고 : 2013.01.23
  • 심사 : 2013.02.07
  • 발행 : 2013.02.28

초록

Quantitative analysis of 5-hydroxymethylfufural (5-HMF) conversion from fructose by dehydration and rearrangement was investigated by $^1H$-NMR spectroscopic method. Fructose was converted to 5-HMF in dimethylsulfoxide (DMSO)-$d^6$ or acidic deuterium hydroxide at controlled reaction temperature and time. With addition of internal standards (biphenyl for DMSO-$d^6$ solvent, and 2,5-dihydroxybenzoic acid for deuterium oxide solvent), conversion from fructose to 5-HMF was analyzed by $^1H$-NMR spectroscopy. Quantitative analysis was run by comparison with peak area integration between of 5-HMF and internal standard. In DMSO solvent, 5-HMF was stable end product but part of 5-HMF was converted to formic and levulinic acid at acidic aqueous medium.

키워드

참고문헌

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피인용 문헌

  1. Conversion of Fructose to 5-HMF(5-hydroxymethylfurfural) in DMSO(dimethylsulfoxide) solvent vol.45, pp.2, 2013, https://doi.org/10.7584/ktappi.2013.45.2.021
  2. H-NMR spectroscopy vol.46, pp.3, 2014, https://doi.org/10.7584/ktappi.2014.46.3.037