Journal of Periodontal and Implant Science

  • 제43권4호
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  • Pages.177-182
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  • 2013
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  • 2093-2278(pISSN)
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  • 2093-2286(eISSN)
대한치주과학회 (Korean Academy of Periodontology)
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Efficacy of nonsurgical periodontal therapy on glycaemic control in type II diabetic patients: a randomized controlled clinical trial

  • Telgi, Ravishankar Lingesha (Department of Public Health Dentistry, Kothiwal Dental College & Research Centre) ;
  • Tandon, Vaibhav (Department of Public Health Dentistry, Kothiwal Dental College & Research Centre) ;
  • Tangade, Pradeep Shankar (Department of Public Health Dentistry, Kothiwal Dental College & Research Centre) ;
  • Tirth, Amit (Department of Public Health Dentistry, Kothiwal Dental College & Research Centre) ;
  • Kumar, Sumit (Department of Public Health Dentistry, Kothiwal Dental College & Research Centre) ;
  • Yadav, Vipul (Department of Public Health Dentistry, Kothiwal Dental College & Research Centre)
  • 투고 : 2013.03.20
  • 심사 : 2013.08.13
  • 발행 : 2013.08.31
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초록

Purpose: Diabetes and periodontal disease are two common diseases with high prevalence rates. Recent evidence has shown a bidirectional relationship between diabetes and periodontitis. The aim of this study was to investigate the effects of nonsurgical periodontal therapy on glycemic control in type 2 diabetes mellitus patients. Methods: Sixty subjects aged 35-45 years with blood sugar controlled by oral hypoglycaemic agents were randomly divided equally among 3 groups: group A (scaling, mouthwash, and brushing), group B (mouthwash and brushing), and group C (brushing only). Glycated haemoglobin (HbA1c), fasting blood sugar (FBS), probing pocket depth (PPD), gingival index (GI), plaque index (PI), and the relevant drug history were recorded at baseline and after 3 months of intervention. Comparison of the mean difference among the variables was performed by parametric and nonparametric tests, which were further evaluated using multiple regression analysis. Results: The mean differences between the PPD, FBS, HbA1c, GI, and PI in groups A and B were found to be statistically significant (P<0.001). Multiple regression analysis in group A showed that out of all the independent variables, GI and frequency of drug administration independently (b=0.3761 and b=0.598) showed a significantly greater impact on HbA1c ($R^2$=0.832, P<0.05). Conclusions: Nonsurgical periodontal therapy can effectively decrease HbA1c levels in type 2 diabetes mellitus patients on medication.

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참고문헌

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피인용 문헌

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  2. Effects of Periodontal Therapy on Metabolic Control in Patients With Type 2 Diabetes Mellitus and Periodontal Disease : A Meta-Analysis vol.93, pp.28, 2013, https://doi.org/10.1097/md.0000000000000292
  3. Oral Manifestations of Diabetes vol.34, pp.1, 2013, https://doi.org/10.2337/diaclin.34.1.54
  4. Periodontal treatment and glycaemic control in patients with diabetes and periodontitis: an umbrella review vol.61, pp.2, 2013, https://doi.org/10.1111/adj.12413
  5. The effect of periodontal therapy on glycemic control and fasting plasma glucose level in type 2 diabetic patients: systematic review and meta-analysis vol.17, pp.None, 2013, https://doi.org/10.1186/s12903-016-0249-1
  6. Nonsurgical periodontal-therapy improves glycosylated hemoglobin levels in pre-diabetic patients with chronic periodontitis vol.8, pp.5, 2017, https://doi.org/10.4239/wjd.v8.i5.213
  7. The Impact of Resveratrol Supplementation on Blood Glucose, Insulin, Insulin Resistance, Triglyceride, and Periodontal Markers in Type 2 Diabetic Patients with Chronic Periodontitis vol.31, pp.1, 2017, https://doi.org/10.1002/ptr.5737
  8. The effects of non-surgical periodontal treatment on glycemic control, oxidative stress balance and quality of life in patients with type 2 diabetes: A randomized clinical trial vol.12, pp.11, 2013, https://doi.org/10.1371/journal.pone.0188171
  9. Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study vol.19, pp.7, 2013, https://doi.org/10.3390/ijms19071949
  10. Adjunctive Effect of Doxycycline with Conventional Periodontal Therapy on Glycemic Level for Chronic Periodontitis with Type 2 Diabetes Mellitus Subjects vol.20, pp.12, 2013, https://doi.org/10.5005/jp-journals-10024-2722
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