참고문헌
- Alia M, S Ramos, R Mateos, AB Granado-Serrano, L Bravo and L Goya. 2006. Quercetin protects human hepatoma HepG2 against oxidative stress induced by tert-butyl hydroperoxide. Toxicol. Appl. Pharmacol. 212:110-118. https://doi.org/10.1016/j.taap.2005.07.014
-
Bak MJ, M Jun and WS Jeong. 2012. Antioxidant and Hepatoprotective effects of the red ginseng essential oil in
$H_2O_2$ -treated HepG2 cells and$CCl_4$ -treated mice. Int. J. Mol. Sci. 12:2314-2330. - Bradford MM. 1976. Rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254. https://doi.org/10.1016/0003-2697(76)90527-3
- Chakraborty D, A Mukherjee, S Sikdar, A Paul, S Ghosh and AR Khuda-Bukhsh. 2012. [6]-Gingerol isolated from ginger attenuates sodium arsenite induced oxidative stress and plays a corrective role in improving insulin signaling in mice. Toxicol. Lett. 210:34-43. https://doi.org/10.1016/j.toxlet.2012.01.002
- Chmielewski AG and MH Saeid. 2004. Radiation technologies: past, present and future. Radiat. Phys. Chem. 71:16-20.
- Curtin JF, M Donovan and TG Cotter. 2002. Regulation and measurement of oxidative stress in apoptosis. J. Immunol. Methods 265:49-72. https://doi.org/10.1016/S0022-1759(02)00070-4
- Devasagayam TPA, JC Tilak, KK Boloor, KS Sane, SS Ghaskadbi and RD Lele. 2004. Free radical and Antioxidants in human health: Current status and future prospects. JAPI 52:794-804.
- Dugasani S, MR Pichika, VD Nadarajah, MK Balijepalli, S Tandra and JN Korlakunta. 2010. Comparative antioxidant and anti-inflammatory effects of [6]-Gingerol, [8]-Gingerol, [10]-Gingerol and [6]-Shogaol. J. Ethnopharmacol. 127:515-520. https://doi.org/10.1016/j.jep.2009.10.004
- Duthie SJ, W Johnson and VL Dobson. 1997. The effect of dietary flavonoids on DNA damage (strand breaks and oxidized pyrimidines) and growth in human cells. Mutat. Res. 390:141-151. https://doi.org/10.1016/S0165-1218(97)00010-4
- Held KD. 1997. Radiation induced apoptosis and its relationship to loss of clonogenic survival. Apoptosis 2:265-282. https://doi.org/10.1023/A:1026485003280
- Hosseinimehr SJ. 2007. Foundation review: Trends in the development of radioprotective agents. Drug Discovery Today. 12:794-805. https://doi.org/10.1016/j.drudis.2007.07.017
- Jauregui HO, NT Hayner, JL Driscoll, W Holland, MH Lipsky and PM Galletti. 1981. Trypan blue dye uptake and lactate dehydrogenase in adult rat hepatocytes freshly isolated cells, cell suspensions, and primary monolayer cultures. In vitro 17:1100-1110. https://doi.org/10.1007/BF02618612
- Kim EC, JK Min, TY Kim, SJ Lee, HO Yang, S Han, YM Kim and YG Kwon. 2005. [6]-Gingerol, a pungent ingredient of ginger, inhibits angiogenesis in vitro and in vivo. Biochem. Biophys. Res. Commun. 335:300-308. https://doi.org/10.1016/j.bbrc.2005.07.076
- Kim JK, Y Kim, KM Na, YJ Surh and TY Kim. 2007. 6-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo. Free Radic. Res. 41:603-614. https://doi.org/10.1080/10715760701209896
- Kunwar A and KI Priyadarsini. 2011. Free radicals, oxidative stress and importance of antioxidants in human health. J. Med. Allied Sci. 1:53-60.
-
Lee C, GH Park, CY Kim and JH Jang. 2011. [6]-Gingerol attenuates
${\beta}$ -amyloid induced oxidative cell death via fortifying cellular antioxidant defense system. Food Chem. Toxicol. 49:1261-1269. https://doi.org/10.1016/j.fct.2011.03.005 - Lipkin M, B Reddy, H Newmark and SA Lamprecht. 1999. Dietary factors in human colorectal cancer. Annu. Rev. Nutr. 19:545-586. https://doi.org/10.1146/annurev.nutr.19.1.545
- Lv L, H Chen, D Soroka, X Chen, TC Leung and S Sang. 2012. 6-Gingerdiols as the major metabolites of 6-Gingerol in cancer cells and in mice and their cytotoxic effects on human cancer cells. J. Agric. Food Chem. 60:11372-11377. https://doi.org/10.1021/jf303879b
- Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-63. https://doi.org/10.1016/0022-1759(83)90303-4
- Moulder JE. 2004. Post irradiation approaches to treatment of radiation injuries in the context of radiological terrorism and radiation accidents: a review. Int. J. Radiat. Biol. 80:3-10. https://doi.org/10.1080/09553000310001642920
- Nigam N, K Bhui, S Prasad, J George and Y Shukla. 2009. [6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells. Chem. Biol. Interact. 181:77-84. https://doi.org/10.1016/j.cbi.2009.05.012
- Noroozi M, WJ Angerson and MEJ Lean. 1998. Effects of flavonoids and vitamin-C on oxidative DNA damage to human lymphocytes. Am. J. Clin. Nutr. 67:1210-1218.
- Riley PA. 1994. Free radicals in biology: oxidative stress and effects of ionizing radiation. Int. J. Radiat. Biol. 65:27-33. https://doi.org/10.1080/09553009414550041
- Ryan JL. 2012. Ionizing radiation: The good, the bad and the ugly. J. Invest. Dermatol. 132:985-993. https://doi.org/10.1038/jid.2011.411
- Shukla Y and M Singh. 2007. Cancer preventive properties of ginger: A brief review. Food Chem. Toxicol. 45:683-690. https://doi.org/10.1016/j.fct.2006.11.002
- Shukla Y, S Prasad, C Tripathi, M Singh, J George and N Kalra. 2007. In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol. Mol. Nutr. Food Res. 51:1492-1502. https://doi.org/10.1002/mnfr.200700197
- Weiss JF and MR Landauer. 2003. Protection against ionizing radiation by antioxidant nutrients and phytochemicals. Toxicology 189:1-20. https://doi.org/10.1016/S0300-483X(03)00149-5
- White B. 2007. Ginger: An overview. American Family Physician 75:1690-1691.